Results 271 to 280 of about 513,814 (378)

Gas Bubbles from Biodegradable Magnesium Implants Convey Mechanical Cues and Promote Immune Cell Stimulation

Advanced Science, EarlyView.
Bubbles in soft tissue are the unavoidable consequence of magnesium implant degradation in patients, yet their biological significance remains unclear. Using advanced imaging and spatial transcriptomics, this study reveals a pronounced inflammatory and mechanical response near bubbles, contrasting with pro‐regenerative events closer to the implant ...
Heithem Ben Amara, Jincy Philip, Omar Omar, Peter Thomsen   +3 more
wiley   +1 more source

Dehydrodiisoeugenol alleviates palmitate-induced mitochondrial dysfunction in human vascular smooth muscle cells through the activation of SIRT1-mediated Drp1 deacetylation. [PDF]

Lipids Health Dis
Zhao J, Shu Z, Li X, Zhang W, Sun M, Song W, Cheng H, Shi S.   +7 more
europepmc   +1 more source

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Advanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang, Sirui Shen, Weixin Li, Mengyang Wang, Yudie Yang, Wu Luo, Xue Han, Zheng Xu, Julian Min, Xiaohong Long, Weijian Huang, Gaojun Wu, Yi Wang, Guang Liang   +13 more
wiley   +1 more source

Monotropein resists atherosclerosis by reducing inflammation, oxidative stress, and abnormal proliferation and migration of vascular smooth muscle cells. [PDF]

Korean J Physiol Pharmacol
Li H, Ye B, Tian J, Wang B, Zha Y, Zheng S, Ma T, Zhuang W, Park WS, Liang J.   +9 more
europepmc   +1 more source

Ultrasound‐Responsive Piezoelectric Membrane Promotes Osteoporotic Bone Regeneration via the “Two‐Way Regulation” Bone Homeostasis Strategy

Advanced Science, EarlyView.
Patients with osteoporosis face a higher risk of bone injury, mainly due to weakened osteogenic differentiation and bone formation, along with increased osteoclast differentiation and bone resorption activity, leading to bone homeostasis imbalance.
Xinhui Wu, Tianlong Wang, Jinhui Zhao, Lei Zhang, Zhiqing Liu, Yixing Chen, Yiping Luo, Yaqi Liu, Yan Chen, Hui Jiang, Dilixiati Duolikun, Junjian Liu, Wentao Cao, Longpo Zheng   +13 more
wiley   +1 more source

<i>O</i>-GlcNAcylation and Phosphorylation Crosstalk in Vascular Smooth Muscle Cells: Cellular and Therapeutic Significance in Cardiac and Vascular Pathologies. [PDF]

Int J Mol Sci
Bolanle IO, Palmer TM.
europepmc   +1 more source

Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells

Circulation Research, 2009
A. Lyle, Nita N. Deshpande, Y. Taniyama, B. Seidel-Rogol, Lily Pounkova, P. Du, Christopher A Papaharalambus, B. Lassègue, K. Griendling   +8 more
semanticscholar   +1 more source

Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label

Advanced Science, EarlyView.
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong, Xiaohui Wang, Jintao Yu, Li Wen, Chengwen Zheng, Ge Yin, Kai Xu, Weiwei He, Hao Wang, Xiaoli Lan, Dawei Jiang, Yu Sun   +11 more
wiley   +1 more source

C/EBPβ activation in vascular smooth muscle cells promotes hyperlipidemia-induced phenotypic transition and arterial stiffness. [PDF]

Signal Transduct Target Ther
Ma J, Yang X, Li Y, Zhang X, Liu K, Peng Y, Wang S, Shi R, Huo X, Liu X, Li X, Ye R, Zhang Z, Yang C, Liu L, Gao D, Jia S, Sun L, Zuo X, Meng Q, Chen X.   +20 more
europepmc   +1 more source

Uric Acid Stimulates Monocyte Chemoattractant Protein‐1 Production in Vascular Smooth Muscle Cells Via Mitogen‐Activated Protein Kinase and Cyclooxygenase‐2

HYPERTENSION, 2003
J. Kanellis, Susumu Watanabe, Jin H Li, D. Kang, Ping Li, T. Nakagawa, A. Wamsley, D. Sheikh-Hamad, H. Lan, Lili Feng, Richard J. Johnson   +10 more
semanticscholar   +1 more source