Results 271 to 280 of about 428,994 (362)

Targeting USP21 to inhibit abdominal aortic aneurysm progression by suppressing the phenotypic transition of vascular smooth muscle cells. [PDF]

Cell Rep Med
Zhang H, Yue H, Sun Y, Sun G, Yang K, Jiang T, Cui S, Liu Y, Guo Y, Zhang W, Zhang C, Chen Y, Xu F.   +12 more
europepmc   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

Interleukin-1 Signaling on Vascular Smooth Muscle Cells Accelerates Atherosclerosis in a Murine Model of Kawasaki Disease. [PDF]

J Am Heart Assoc
Chen S, Savas A, Atici A, Lee Y, Lane M, Aubuchon E, Moreira D, Hsu-Wilbraham A, Shimada K, Crother TR, Noval Rivas M, Arditi M.   +11 more
europepmc   +1 more source

A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation

Advanced Science, EarlyView.
A hyaluronic acid methacrylate (HAMA) hydrogel incorporating DNA tetrahedrons loaded with Asiatic acid (TDN@AA) was developed. HM‐TDN@AA promotes angiogenesis of endothelial cells (ECs), inhibits osteoclastogenesis from bone marrow–derived macrophages (BMDMs), and enhances osteogenesis of mesenchymal stem cells (MSCs) via STAT3‐mediated mitochondrial ...
Yiwen Huang, Yiming Zhang, Yisheng Feng, Qixiang Yang, Beiyuan Gao, Haiyang Xu, Cheng Huang, Kaili Lin, Yuanzhi Xu, Peiqi Zhu   +9 more
wiley   +1 more source

Evogliptin prevents ceramide-induced pyroptosis during calcification via modulation of NLRP3/GSDM-D mediated pathway in Vascular Smooth Muscle Cells. [PDF]

PLoS One
Rahil RR, Shamas S, Wani NA, Nanda N, Ahmad SF, Attia SM, Hamid A, Zargar MA, Bhat OM.   +8 more
europepmc   +1 more source

Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) differentially modulate angiotensin II effects on vascular smooth muscle cells

, 2017
Subhadeep Chakrabarti, Wang Liao, Sandra T. Davidge, Jian Wu   +3 more
openalex   +2 more sources

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Egr‑1 promotes the proliferation and migration of vascular smooth muscle cells by transcriptionally activating Egr‑2 in arteriovenous fistulas. [PDF]

Int J Mol Med
Hu K, Bu S, Guo Y, Li Y, Yu S, Wang L, Cai C, Li Y, Liu X, Huang H, Wang W.   +10 more
europepmc   +1 more source

Transdifferentiation of endothelial cells to smooth muscle cells play an important role in vascular remodelling.

, 2015
Núria Coll-Bonfill, Melina M. Musri, Victor Ivo, Joan Albert Barberà, Olga Tura-Ceide   +4 more
openalex   +1 more source

Poly(ADP-ribose) protects vascular smooth muscle cells from oxidative DNA damage

, 2015
Chao Zhang, Tao Luo, Shijun Cui, Yongquan Gu, Chunjing Bian, Yibin Chen, Xiaochun Yu, Zhonggao Wang   +7 more
openalex   +2 more sources