Results 61 to 70 of about 236,010 (265)

Short Chain (≤C4) Esterification Increases Bioavailability of Rosmarinic Acid and Its Potency to Inhibit Vascular Smooth Muscle Cell Proliferation

Frontiers in Pharmacology, 2021
Rosmarinic acid is a natural phenolic acid and active compound found in many culinary plants, such as rosemary, mint, basil and perilla. Aiming to improve the pharmacokinetic profile of rosmarinic acid and its activity on vascular smooth muscle cell ...
Tina Blažević, Gottfried Reznicek, Limin Ding, Gangqiang Yang, Patricia Haiss, Elke H. Heiss, Verena M. Dirsch, Rongxia Liu   +7 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Research advances on the role of Runx2-related miRNAs in vascular calcification of chronic kidney disease

Linchuang shenzangbing zazhi, 2022
Vascular calcification （VC） is a major cause of cardiovascular mortality in patients with chronic kidney disease （CKD）. Current studies suggest that VC of CKD is not simply an ectopic deposition of calcium phosphate crystals in vascular wall.
Lu Yang-yang, Bai Ya-ling, Xu Jin-sheng
doaj  

Cell Autonomous and Non-cell Autonomous Regulation of SMC Progenitors in Pulmonary Hypertension

Cell Reports, 2018
Summary: Pulmonary hypertension is a devastating disease characterized by excessive vascular muscularization. We previously demonstrated primed platelet-derived growth factor receptor β+ (PDGFR-β+)/smooth muscle cell (SMC) marker+ progenitors at the ...
Abdul Q. Sheikh, Fatima Zahra Saddouk, Aglaia Ntokou, Renata Mazurek, Daniel M. Greif   +4 more
doaj   +1 more source

Purinergic Signaling During Hyperglycemia in Vascular Smooth Muscle Cells

Frontiers in Endocrinology, 2020
The activation of purinergic receptors by nucleotides and/or nucleosides plays an important role in the control of vascular function, including modulation of vascular smooth muscle excitability, and vascular reactivity.
Miguel Martin-Aragon Baudel, Ricardo Espinosa-Tanguma, Madeline Nieves-Cintron, Manuel F. Navedo   +3 more
doaj   +1 more source

Gasdermin D affects aortic vascular smooth muscle cell pyroptosis and Ang II-induced vascular remodeling

Heliyon, 2023
Vascular smooth muscle cells (VSMCs) are primarily responsible for vasoconstriction and the regulation of blood pressure1. Pyroptosis, a particular form of regulated cell death, is involved in multiple vascular injuries, including hypertensive vascular ...
Zimin Fang, Gaojun Wu, Jian Sheng, Bozhi Ye, Zhouqing Huang, Jianjiang Xu, Jianqin Zhang, Jibo Han, Bingjiang Han, Jiajun Xu   +9 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

The regulation of vascular smooth muscle cell apoptosis [PDF]

Cardiovascular Research, 2000
Apoptosis describes the morphological changes that identify a specific form of regulated cell death. Over recent years, the importance of either aberrant onset or suppression of apoptosis within tissues has become apparent and is associated with the development of several terminal diseases. Here we describe the relevance of apoptosis to the maintenance
N J, McCarthy, M R, Bennett
openaire   +2 more sources

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Quantification of alignment of vascular smooth muscle cells [PDF]

Cytometry Part A, 2018
AbstractVascular smooth muscle cells (VSMCs) are essential components that keep the tonus of the arterial network, which is the channel used to conduct the blood from the heart to the peripheral areas of the body. It is known that mechanical and architectural changes in VSMCs may lead to functional modifications in the cardiovascular system; therefore,
Marcel P, Dorta, Isis V, de Brito, Alexandre C, Pereira, Adriano M, Alencar   +3 more
openaire   +2 more sources