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Frontiers in Cardiovascular Medicine, 2023 BackgroundArterial stiffness and medial vascular calcification, leading to isolated systolic blood pressure (BP), are major cardiovascular risk factors in patients with chronic kidney disease (CKD) and mineral bone disorders (MBD).
Richard Larivière +9 more
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Substrate stiffness differentially impacts autophagy of endothelial cells and smooth muscle cells
Bioactive Materials, 2021 Stiffening of blood vessels is one of the most important characteristics in the process of many cardiovascular pathologies such as atherosclerosis, angiosteosis, and vascular aging.
Mi Hu +9 more
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Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness. [PDF]
Cell MetabRachedi NS +33 more
europepmc +2 more sources
Frontiers in Cell and Developmental Biology, 2021 The arterial mechanical microenvironment, including stiffness, is a crucial pathophysiological feature of vascular remodeling, such as neointimal hyperplasia after carotid endarterectomy and balloon dilatation surgeries.
H. Bao +12 more
semanticscholar +1 more source
Substrate stiffness directs diverging vascular fates [PDF]
Acta Biomaterialia, 2019 Embryonic stem cells (ESC) are excellent cell culture systems for elucidating developmental signals that may be part of the stem cell niche. Although stem cells are traditionally induced using predominately soluble signals, the mechanical environment of the niche can also play a role in directing cells towards differential cell lineages.
Lian Wong +8 more
openaire +3 more sources
Reversal of aging-induced increases in aortic stiffness by targeting cytoskeletal protein-protein interfaces [PDF]
, 2018 Background: The proximal aorta normally functions as a critical shock absorber that protects small downstream vessels from damage by pressure and flow pulsatility generated by the heart during systole.
AortaGen Consortium, the +20 more
core +5 more sources
Association of vascular stiffness and geriatric syndromes in hypertensive elderly patients
Российский кардиологический журнал, 2021 Aim. To study the relationship of vascular stiffness (cardio-ankle vascular index (CAVI)) with frailty and other geriatric syndromes in hypertensive elderly patients.Material and methods. The study included 160 patients aged 60 to 101 years with verified
A. V. Luzina +3 more
doaj +1 more source
Cardiovascular Diabetology, 2021 Objective Cardiac diastolic dysfunction (DD) and arterial stiffness are early manifestations of obesity-associated prediabetes, and both serve as risk factors for the development of heart failure with preserved ejection fraction (HFpEF).
A. Aroor +8 more
semanticscholar +1 more source
Arterial Stiffness and Vascular Aging: Effects of Hypertension
Архивъ внутренней медицины, 2021 This review highlights the relationship of age and arterial hypertension observed in the aging process. The main structural and functional changes underlying the increase in vascular stiffness are analyzed. The similarity of vascular changes in aging and
E. S. Fomina, V. S. Nikiforov
doaj +1 more source