Results 41 to 50 of about 1,797,457 (225)

The Causal Relationship between Endothelin-1 and Hypertension: Focusing on Endothelial Dysfunction, Arterial Stiffness, Vascular Remodeling, and Blood Pressure Regulation

open access: yesLife, 2021
Hypertension (HTN) is one of the most prevalent diseases worldwide and is among the most important risk factors for cardiovascular and cerebrovascular complications.
K. Kostov
semanticscholar   +1 more source

Substrate stiffness differentially impacts autophagy of endothelial cells and smooth muscle cells

open access: yesBioactive Materials, 2021
Stiffening of blood vessels is one of the most important characteristics in the process of many cardiovascular pathologies such as atherosclerosis, angiosteosis, and vascular aging.
Mi Hu   +9 more
doaj  

Age and vascular aging: an unexplored frontier

open access: yesFrontiers in Cardiovascular Medicine, 2023
Vascular age is an emerging field in cardiovascular risk assessment. This concept includes multifactorial changes in the arterial wall, with arterial stiffness as its most relevant manifestation, leading to increased arterial pressure and pulsatile flow ...
Laura del Mar González   +4 more
doaj   +1 more source

Holographic Cell Stiffness Mapping Using Acoustic Stimulation [PDF]

open access: yesarXiv, 2021
Accurate assessment of stiffness distribution is essential due to the critical role of single cell mechanobiology in the regulation of many vital cellular processes such as proliferation, adhesion, migration, and motility. Cell stiffness is one of the fundamental mechanical properties of the cell and is greatly affected by the intracellular tensional ...
arxiv  

Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]

open access: yes, 2016
Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio   +9 more
core   +1 more source

Vascular age concept: role in assessing risk and choosing therapy

open access: yesМедицинский совет, 2020
The article discusses the vascular age concept and modern approaches to assessing vascular age. It describes modern methods for measuring arterial stiffness (applanation tonometry or ultrasonic Doppler examination) as the most frequently used index of ...
S. R. Gilyarevsky   +5 more
doaj   +1 more source

Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.

open access: yesJournal of Clinical Investigation, 2016
Dysregulation of vascular stiffness and cellular metabolism occurs early in pulmonary hypertension (PH). However, the mechanisms by which biophysical properties of the vascular extracellular matrix (ECM) relate to metabolic processes important in PH ...
T. Bertero   +30 more
semanticscholar   +1 more source

The cardiovascular phenotype of adult patients with phenylketonuria [PDF]

open access: yes, 2019
BACKGROUND: Patients with Phenylketonuria (PKU) are exposed to multiple cardiovascular risk factors, but the clinical significance of these abnormalities is yet unknown.
Azabdaftari, Aline   +5 more
core   +1 more source

Impact of Sex on Ventricular‐Vascular Stiffness and Long‐Term Outcomes in Heart Failure With Preserved Ejection Fraction: TOPCAT Trial Substudy

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2019
Background Women have higher vascular stiffness with aging. The aim of this study was to characterize sex differences in vascular and ventricular structure and function, and to investigate the impact on the primary outcome in the TOPCAT trial (Treatment ...
A. Beale, S. Nanayakkara, D. Kaye
semanticscholar   +1 more source

Circulating adhesion molecules and arterial stiffness [PDF]

open access: yes, 2015
Aim: VCAM-1 and ICAM-1 are two important members of the immunoglobulin gene superfamily of adhesion molecules, and their potential role as biomarkers of diagnosis, severity and prognosis of cardiovascular disease has been investigated in a number of ...
Alihanoglu, Y.I.   +6 more
core   +2 more sources

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