Results 71 to 80 of about 1,799,199 (341)

Effects of biomechanical and biochemical stimuli on angio- and vasculogenesis in a complex microvasculature-on-chip

iScience, 2023
Summary: The endothelium of blood vessels is a vital organ that reacts differently to subtle changes in stiffness and mechanical forces exerted on its environment (extracellular matrix (ECM)).
Dario Ferrari, Arunima Sengupta, Lyong Heo, Laszlo Pethö, Johann Michler, Thomas Geiser, Vinicio A. de Jesus Perez, Wolfgang M. Kuebler, Soheila Zeinali, Olivier T. Guenat   +9 more
doaj   +1 more source

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

Arthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

Role of Echocardiography in Evaluation of the Effects of Sacubitril–Valsartan on Vascular Stiffness in Patients with Heart Failure: Review Article [PDF]

, 2022
Elshaimaa Ali Elsadek Seaoud, Tarek Ahmad Naguib, Ismail Talha Elbarky, Moataz Abdelmonem Elkot   +3 more
openalex   +1 more source

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

Arthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
wiley   +1 more source

Minoxidil improves vascular compliance, restores cerebral blood flow, and alters extracellular matrix gene expression in a model of chronic vascular stiffness.

American Journal of Physiology. Heart and Circulatory Physiology, 2018
Increased vascular stiffness correlates with a higher risk of cardiovascular complications in aging adults. Elastin (ELN) insufficiency, as observed in patients with Williams-Beuren syndrome or with familial supravalvular aortic stenosis, also increases ...
Russell H Knutsen, S. Beeman, T. Broekelmann, Delong Liu, K. Tsang, A. Kovács, Li Ye, Joshua R. Danback, Anderson Watson, Amanda Wardlaw, J. Wagenseil, J. Garbow, Michael Shoykhet, B. Kozel   +13 more
semanticscholar   +1 more source

Mitochondrial Contributions to Vascular Endothelial Dysfunction, Arterial Stiffness and Cardiovascular Diseases.

American Journal of Physiology. Heart and Circulatory Physiology, 2021
Cardiovascular diseases (CVD) affect 1 in 3 adults and remain the leading causes of death in America. Advancing age is the major risk factor for CVD.
D. Kirkman, Austin T. Robinson, Matthew J. Rossman, D. Seals, D. Edwards   +4 more
semanticscholar   +1 more source

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez, Pinar Ozge Avar‐Aydin, Kelly Rogers, Daniel J. Lovell, Jennifer Huggins, Alexei Grom, Hermine I. Brunner, Grant S. Schulert, Sheila T. Angeles‐Han, Mekibib Altaye, Amy Cassedy, Arthur B. Meyers, Tracy V. Ting   +12 more
wiley   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Dissociation of pulse wave velocity and aortic wall stiffness in diabetic db/db mice: The influence of blood pressure

Frontiers in Physiology, 2023
Introduction: Vascular stiffness is a predictor of cardiovascular disease and pulse wave velocity (PWV) is the current standard for measuring in vivo vascular stiffness.
Patricia E. McCallinhart, Patricia E. McCallinhart, Yong Ung Lee, Yong Ung Lee, Avione Lee, Avione Lee, Mircea Anghelescu, Jeffrey R. Tonniges, Ed Calomeni, Gunjan Agarwal, Gunjan Agarwal, Joy Lincoln, Joy Lincoln, Joy Lincoln, Aaron J. Trask, Aaron J. Trask, Aaron J. Trask, Aaron J. Trask   +17 more
doaj   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source