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Application of E-coach chronic disease management model in rehabilitation management of patients with arteriosclerosis obliterans

open access: yesJournal of Health, Population and Nutrition, 2023
Objective To explore the effect of a health (E)-coach chronic disease management model on the rehabilitation behaviour management of patients with arteriosclerosis obliterans (ASO).
You-Yuan Yuan   +8 more
doaj   +1 more source

Nanogold Functionalized With Lipoamide-isoDGR: A Simple, Robust and Versatile Nanosystem for αvβ3-Integrin Targeting

open access: yesFrontiers in Chemistry, 2021
Gold nanoparticles functionalized with isoDGR, a tripeptide motif that recognizes αvβ3 integrin overexpressed in tumor vessels, have been used as nano-vectors for the delivery of cytokines to tumors.
Angelina Sacchi   +8 more
doaj   +1 more source

VACStent: Combining the benefits of endoscopic vacuum therapy and covered stents for upper gastrointestinal tract leakage

open access: yesEndoscopy International Open, 2021
Background and study aims Endoscopic treatment has markedly improved the high morbidity and mortality in patients with upper gastrointestinal tract leakage.
Jonas Lange   +5 more
doaj   +1 more source

Enhancement of doxorubicin anti-cancer activity by vascular targeting using IsoDGR/cytokine-coated nanogold

open access: yesJournal of Nanobiotechnology, 2021
Background Gold nanospheres tagged with peptides containing isoDGR (isoAsp-Gly-Arg), an αvβ3 integrin binding motif, represent efficient carriers for delivering pro-inflammatory cytokines to the tumor vasculature.
Angelo Corti   +8 more
doaj   +1 more source

Acrolein-inducing ferroptosis contributes to impaired peripheral neurogenesis in zebrafish

open access: yesFrontiers in Neuroscience, 2023
IntroductionDiabetes mellitus (DM) is associated with physiological disorders such as delayed wound healing, diabetic retinopathy, diabetic nephropathy, and diabetic peripheral neuropathy (DPN).
Haozhe Qi   +9 more
doaj   +1 more source

Metabolic and Transcriptional Adaptations Improve Physical Performance of Zebrafish

open access: yesAntioxidants, 2021
Obesity is a worldwide public health problem with increasing prevalence and affects 80% of diabetes mellitus type 2 cases. Zebrafish (Danio rerio) is an established model organism for studying obesity and diabetes including diabetic microvascular ...
Franziska J. Heinkele   +6 more
doaj   +1 more source

Comparative Morphological, Metabolic and Transcriptome Analyses in elmo1−/−, elmo2−/−, and elmo3−/− Zebrafish Mutants Identified a Functional Non-Redundancy of the Elmo Proteins

open access: yesFrontiers in Cell and Developmental Biology, 2022
The ELMO protein family consists of the homologues ELMO1, ELMO2 and ELMO3. Several studies have shown that the individual ELMO proteins are involved in a variety of cellular and developmental processes.
Mike Boger   +6 more
doaj   +1 more source

Transvaginal hybrid-NOTES vs. traditional laparoscopic sigmoid resection for diverticulitis: a short-term comparative study

open access: yesScientific Reports, 2020
The aim was to compare short-term results of transvaginal hybrid-NOTES (NSR) with traditional laparoscopic technique in sigmoid resection (LSR) in cases of diverticulitis.
Marie Derstadt   +7 more
doaj   +1 more source

The use and future perspective of Artificial Intelligence—A survey among German surgeons

open access: yesFrontiers in Public Health, 2022
PurposeClinical abundance of artificial intelligence has increased significantly in the last decade. This survey aims to provide an overview of the current state of knowledge and acceptance of AI applications among surgeons in Germany.MethodsA total of ...
Mathieu Pecqueux   +14 more
doaj   +1 more source

Inhibition of Tumor Growth and Angiogenesis by Soluble EphB4

open access: yesNeoplasia: An International Journal for Oncology Research, 2004
EphB receptors and their ephrinB ligands play a key role in the formation of a regular vascular system. Recent studies have also shown the involvement of Eph/ephrin interactions in malignant tumor progression and angiogenesis.
Georg Martiny-Baron   +6 more
doaj   +1 more source

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