Results 21 to 30 of about 752,279 (217)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

MRI radiomics and 90Y PET dosimetry for predicting hepatocellular carcinoma response after radioembolization

BMC Cancer
Background To evaluate treatment response in hepatocellular carcinoma (HCC) following Yttrium-90 (90Y) radioembolization by integrating pre-treatment contrast-enhanced magnetic resonance imaging (CE-MRI) radiomics with post-treatment 90Y positron ...
Wenyu Huang, Jie Ding, Hongzhen Yuan, Zhidong Li, Huai Li, Yinglang Zeng   +5 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Indurated dusky red swelling on the forearm of an infant: Tufted angioma

Indian Journal of Dermatology, 2019
Tufted angioma (TA) is a rare benign vascular tumor that may be congenital or acquired and generally presents as an asymptomatic or painful solitary erythematous to violaceous poorly defined plaque. Hyperhidrosis and hypertrichosis may be associated. The
Deepak Jakhar, Archana Singal, Ishmeet kaur, Priya Pathak   +3 more
doaj   +1 more source

Wilson–Jones angiosarcoma of the scalp associated with alopecia and chest edema: a case report

Journal of the Egyptian Women’s Dermatologic Society, 2022
Wilson–Jones angiosarcoma is one of cutaneous angiosarcomas, which is a rare aggressive tumor of blood vessels of the skin. In this case report, we present a 72-year-old female who developed multiple episodes of facial edema of 2-year duration along with
Galal El Enany, Noha Nagui, Hanan Nada, Marwa M Fawzy, Iman Sany, Suzan Shalaby, Omar El Ghanam   +6 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Excision of Recurrent Hemangioma in Hand with Reconstruction Using Abdominal Flap

Folia Medica Indonesiana, 2022
Highlights: • Hemangioma of the hand is a challenging case due to the need to maximize eradication of the mass while minimizing damage to the healthy tissue to preserve the physiologic function of the hand.
Ivan Joalsen Mangara Tua, Andi Mohammad Ardan, Hari Daswin Pagehgiri, Amy Rosalie Sukamto, Made Angga Putra Dwipayana   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Systems biology based elucidation and experimental validation of anticancer effects of warfarin in vulvar cancer

Türk Biyokimya Dergisi
To evaluate the efficacy of warfarin in inhibiting vulvar cancer cell growth and explore its molecular mechanisms, including effects on immune-infiltration and pathways utilizing both computational and experimental approaches.
Liang Jianwei, Yao Qiang, Pi Xingtao, Liu Yuan, Cao Wendong, Wei Shanchen, Feng Wendong   +6 more
doaj   +1 more source