Results 11 to 20 of about 1,741 (203)

Sensitization and Desensitization in Vascularized Composite Allotransplantation [PDF]

Frontiers in Immunology, 2021
Vascularized composite allotransplantation (VCA) is a field under research and has emerged as an alternative option for the repair of severe disfiguring defects that result from severe tissue loss in a selected group of patients. Lifelong immunosuppressive therapy, immunosuppression associated complications, and the effects of the host immune response ...
Moris, Dimitrios, Cendales, Linda C
openaire   +4 more sources

Current status of vascularized composite tissue allotransplantation [PDF]

Burns & Trauma, 2014
Vascularized composite tissue allotransplantation (VCA) offers treatment options of complex functional deficiencies that cannot be repaired with conventional reconstructive methods. VCAs consist of blocks of functional units comprising different tissue types such as skin, bone, muscle, nerves, blood vessels, tendons, ligaments and others, and are thus ...
Edtinger, Karoline, Yang, Xiaoyong, Uehara, Hanae, Tullius, Stefan   +3 more
openaire   +6 more sources

A chronic rejection model and potential biomarkers for vascularized composite allotransplantation.

PLoS ONE, 2020
BackgroundChronic rejection remains the Achilles heel in vascularized composite allotransplantation. Animal models to specifically study chronic rejection in vascularized composite allotransplantation do not exist so far.
Flemming Puscz, Mehran Dadras, Alexander Dermietzel, Frank Jacobsen, Marcus Lehnhardt, Björn Behr, Tobias Hirsch, Maximilian Kueckelhaus   +7 more
doaj   +3 more sources

The Need for Inducing Tolerance in Vascularized Composite Allotransplantation [PDF]

Clinical and Developmental Immunology, 2012
Successful hand and face transplantation in the last decade has firmly established the field of vascularized composite allotransplantation (VCA). The experience in VCA has thus far been very similar to solid organ transplantation in terms of the morbidity associated with long-term immunosuppression.
Kadiyala V. Ravindra, Hong Xu, Larry D. Bozulic, David D. Song, Suzanne T. Ildstad   +4 more
openaire   +4 more sources

Defining chronic rejection in vascularized composite allotransplantation—The American Society of Reconstructive Transplantation and International Society of Vascularized Composite Allotransplantation chronic rejection working group: 2018 American Society of Reconstructive Transplantation meeting report and white paper Research goals in defining chronic rejection in vascularized composite allotransplantation

SAGE Open Medicine, 2020
Objectives: This report summarizes a collaborative effort between the American Society of Reconstructive Transplantation and the International Society of Vascularized Composite Allotransplantation to establish what is known about chronic rejection in ...
Christina L Kaufman, Jean Kanitakis, Annemarie Weissenbacher, Gerald Brandacher, Mandeep R Mehra, Hatem Amer, Bettina G Zelger, Bernhard Zelger, Bohdan Pomahac, Sue McDiarmid, Linda Cendales, Emmanuel Morelon   +11 more
doaj   +2 more sources

Tolerance Induction Strategies in Vascularized Composite Allotransplantation: Mixed Chimerism and Novel Developments [PDF]

Clinical and Developmental Immunology, 2012
Since the start of the clinical vascularized composite allotransplantation (VCA) era over a decade ago this field has witnessed significant developments in both basic and translational research.
David A. Leonard, Duncan A. McGrouther, Josef M. Kurtz, Curtis L. Cetrulo   +3 more
doaj   +2 more sources

Transplantation Direct: The Official Journal of the International Society of Vascularized Composite Allotransplantation [PDF]

Transplantation Direct
Jérôme Duisit, MD, DDS, PhD, Edward Geissler, PhD, Patrik Lassus, MD, PhD, Hatem Amer, MD   +3 more
doaj   +2 more sources

Application possibilities of artificial intelligence in facial vascularized composite allotransplantation-a narrative review. [PDF]

Front Surg, 2023
Facial vascularized composite allotransplantation (FVCA) is an emerging field of reconstructive surgery that represents a dogmatic shift in the surgical treatment of patients with severe facial disfigurements. While conventional reconstructive strategies
Knoedler L, Knoedler S, Allam O, Remy K, Miragall M, Safi AF, Alfertshofer M, Pomahac B, Kauke-Navarro M.   +8 more
europepmc   +3 more sources

[Advances and perspectives in vascularized composite allotransplantation preservation]. [PDF]

Bull Acad Natl Med
Vascularized composite allotransplantation (VCA) involves transplants of the face, upper limb, trachea, penis, abdominal wall and, more recently, uterus. These grafts are unique in that they comprise numerous specialized tissues derived from several embryonic layers, each with its own specific constraints.
Berkane Y, Oubari H, Lupon E, Goutard M, Tawa P, Randolph MA, Cetrulo CL, Bertheuil N, Lellouch AG, Uygun K.   +9 more
europepmc   +4 more sources

Molecular Signature Associated With Acute Rejection in Vascularized Composite Allotransplantation. [PDF]

Transplant Direct
Background. A deeper understanding of acute rejection in vascularized composite allotransplantation is paramount for expanding its utility and longevity. There remains a need to develop more precise and accurate tools for diagnosis and prognosis of these
Cassidy MF, Doudican NA, Frazzette N, Rabbani PS, Carucci JA, Gelb BE, Rodriguez ED, Lu CP, Ceradini DJ.   +8 more
europepmc   +2 more sources