Results 21 to 30 of about 1,741 (203)

Challenges and opportunities in vascularized composite allotransplantation of joints: a systematic literature review. [PDF]

Front Immunol, 2023
BackgroundJoint allotransplantation (JA) within the field of vascularized composite allotransplantation (VCA) holds great potential for functional and non-prosthetic reconstruction of severely damaged joints.
Zhang L, Hoyos IA, Zubler C, Rieben R, Constantinescu M, Olariu R.   +5 more
europepmc   +3 more sources

Preconditioned Mesenchymal Stromal Cells to Improve Allotransplantation Outcome

Cells, 2021
Mesenchymal stromal cells (MSCs) are tissue-derived progenitor cells with immunomodulatory as well as multilineage differentiation capacities, and have been widely applied as cellular therapeutics in different disease systems in both preclinical models ...
Hui-Yun Cheng, Madonna Rica Anggelia, Cheng-Hung Lin, Chih-Fan Lin   +3 more
doaj   +1 more source

Latissimus Dorsi Myocutaneous Flap Procedure in a Swine Model

Journal of Investigative Surgery, 2021
Background As surgical research expands in both breadth and scope, translational models become increasingly important. The accessibility, reproducibility, and clinical applicability of translational models is of vital importance to ensure adequate and ...
Joanna W. Etra, Samuel A. J. Fidder, Christopher M. Frost, Franka Messner, Yinan Guo, Dalibor Vasilic, Sarah E. Beck, Steven Bonawitz, Gerald Brandacher, Damon S. Cooney   +9 more
doaj   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Treatment with selective transcatheter arterial embolization of a ruptured profunda artery perforator after internal thigh liposuction: a case report

Journal of Medical Case Reports, 2023
Background Hemorrhage is an uncommon complication of liposuction that may be trauma-induced by the cannula on the subcutaneous perforators. It usually resolves spontaneously with external compression and results in mild to moderate ecchymosis on the ...
Pierre Tawa, Tom Boeken, Curtis L. Cetrulo, Alexandre G. Lellouch   +3 more
doaj   +1 more source

Sustained Release of Tacrolimus Embedded in a Mixed Thermosensitive Hydrogel for Improving Functional Recovery of Injured Peripheral Nerves in Extremities

Pharmaceutics, 2023
Vascularized composite allotransplantation is an emerging strategy for the reconstruction of unique defects such as amputated limbs that cannot be repaired with autologous tissues.
Aline Yen Ling Wang, Kuan-Hung Chen, Hsiu-Chao Lin, Charles Yuen Yung Loh, Yun-Ching Chang, Ana Elena Aviña, Chin-Ming Lee, I-Ming Chu, Fu-Chan Wei   +8 more
doaj   +1 more source

Costimulation Blockade in Vascularized Composite Allotransplantation [PDF]

Frontiers in Immunology, 2020
Vascular composite allotransplantation (VCA) is a field under research and has emerged as an alternative option for the repair of severe disfiguring defects that result from infections or traumatic amputation in a selected group of patients. VCA is performed in centers with appropriate expertise, experience and adequate resources to effectively manage ...
Giannis, Dimitrios, Moris, Dimitrios, Cendales, Linda C   +2 more
openaire   +3 more sources

Predicting Outcomes of Rat Vascularized Composite Allotransplants through Quantitative Measurement of Chimerism with PCR-Amplified Short Tandem Repeat

Journal of Immunology Research, 2020
Chimerism has been associated with the induction and maintenance of tolerance to vascularized composite allotransplants (VCA). Although most VCA studies have examined chimerism using flow cytometry, we proposed that precision in the measurement of ...
Hui-Yun Cheng, Xiao-Ting Huang, Chih-Fan Lin, Nidal F. AL Deek, Ling-Yi Shih, Cheng-Hung Lin, Fu-Chan Wei   +6 more
doaj   +1 more source

Towards Optimizing Sub-Normothermic Machine Perfusion in Fasciocutaneous Flaps: A Large Animal Study

Bioengineering, 2023
Machine perfusion has developed rapidly since its first use in solid organ transplantation. Likewise, reconstructive surgery has kept pace, and ex vivo perfusion appears as a new trend in vascularized composite allotransplants preservation. In autologous
Yanis Berkane, Alexandre G. Lellouch, Guillaume Goudot, Austin Shamlou, Irina Filz von Reiterdank, Marion Goutard, Pierre Tawa, Paul Girard, Nicolas Bertheuil, Basak E. Uygun, Mark A. Randolph, Jérôme Duisit, Curtis L. Cetrulo, Korkut Uygun   +13 more
doaj   +1 more source

A New Rat Model for Orthotopic Abdominal Wall Allotransplantation

Plastic and Reconstructive Surgery, Global Open, 2014
Background: Abdominal wall, one of the most commonly transplanted composite tissues, is less researched and lacking animal models. Its clinical necessities were emphasized in multiple case series to reconstruct large abdominal defects.
William W. Lao, MD, Yen-Ling Wang, PhD, Alejandro E. Ramirez, MD, Hui-Yun Cheng, PhD, Fu-Chan Wei, MD   +4 more
doaj   +1 more source