Results 71 to 80 of about 4,131 (170)

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, Volume 13, Issue 21, 13 April 2026.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Vasculogenic mimicry: a novel target for glioma therapy

Chinese Journal of Cancer, 2014
Anti-angiogenic therapy has shown promising but insufficient efficacy on gliomas. Recent studies suggest that vasculogenic mimicry (VM), or the formation of non-endothelial, tumor-cell-lined microvascular channels, occurs in aggressive tumors, including gliomas.
Chen, Yin-Sheng, Chen, Zhong-Ping
openaire   +2 more sources

Overview of advances in vasculogenic mimicry – a potential target for tumor therapy

Cancer Management and Research, 2018
Hong Ge,1 Hui Luo1,2 1Department of Radiation Oncology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China; 2Division of Graduate, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, People ...
Ge H, Luo H
doaj  

Supplemental Blood Circulation System in Hematologic Malignancies

Клиническая онкогематология, 2014
Neoangiogenesis, i.e. formation of new blood microvessels on the basis of already existing vascular network, is a prerequisite for tumor growth. For years, neoangiogenesis has been considered the only way for delivering oxygen and nutrients to the tumor.
A. A. Vartanyan
doaj   +1 more source

Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway

Journal of Experimental & Clinical Cancer Research, 2018
Background Tumor microenvironments (TMEs) activate various axes/pathways, predominantly inflammatory and hypoxic responses, impact tumorigenesis, metastasis and therapeutic resistance significantly.
Yen-Hsiu Yeh, Ho-Fu Hsiao, Yen-Cheng Yeh, Tien-Wen Chen, Tsai-Kun Li   +4 more
doaj   +1 more source

Vasculogenic mimicry in gastric cancer

, 2016
Regular
Corvalan, Alejandro H, Valdivia, Andres, Carrasco, Gonzalo, Racordon, Dusan M, Rodriguez, Andres, Sandoval, Alejandra M, Olivares, Wilda, Owen, Gareth   +7 more
openaire   +4 more sources

Advances in vasculogenic mimicry in breast cancer

Zhongguo linchuang yanjiu
Vasculogenic mimicry (VM) is a blood vessel-like structure formed by tumor cells and extracellular matrix, which can mimic the function of blood vessels while providing nutrients to tumors. Tumor angiogenesis plays an important role in tumor cell growth,
TENG Yueyue, ZHOU Guiping， SHI Shiming， HUANG Shengchao， ZHANG Yuanqi
doaj   +1 more source

EXPRESSION OF CONCERN: An Upstream Open Reading Frame Regulates Vasculogenic Mimicry of Glioma via ZNRD1‐AS1/miR‐499a‐5p/ELF1/EMI1 Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
wiley   +1 more source

Vasculogenic mimicry and tumor metastasis.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 2016
Vasculogenic mimicry (VM), a microvascular channel made up of nonendothelial cells, has been accepted as a new model of neovascularization in aggressive tumors, owning to the specific capacity of malignant cells to form vessel-like networks which provide sufficient blood supply for tumor growth.
Jingxin, Zhang, Lili, Qiao, Ning, Liang, Jian, Xie, Hui, Luo, Guodong, Deng, Jiandong, Zhang   +6 more
openaire   +1 more source

The deubiquitinase USP7 and E3 ligase TRIM21 regulate vasculogenic mimicry and malignant progression of RMS by balancing SNAI2 homeostasis

Journal of Experimental & Clinical Cancer Research
Background Rhabdomyosarcoma (RMS) is a rare malignancy and the most common soft tissue sarcoma in children. Vasculogenic mimicry (VM) is a novel tumor microcirculation model different from traditional tumor angiogenesis, which does not rely on ...
Ruyue Zhang, Daidi Zhang, Fugen Han, Xiaorui Song, Yaodong Zhang, Jie Zhang, Qingwen Zhu, Yanru Qin   +7 more
doaj   +1 more source