Results 51 to 60 of about 4,131 (170)

MicroRNA-204 Regulates Angiogenesis and Vasculogenic Mimicry in CD44+/CD24− Breast Cancer Stem-like Cells

open access: yesNon-Coding RNA
Tumors have high requirements in terms of nutrients and oxygen. Angiogenesis is the classical mechanism for vessel formation. Tumoral vascularization has the function of nourishing the cancer cells to support tumor growth.
Martha Resendiz-Hernández   +10 more
doaj   +1 more source

Mig-7 Linked to Vasculogenic Mimicry [PDF]

open access: yesThe American Journal of Pathology, 2007
Solid tumor development consists of a series of stages during which cells undergo genetic and phenotypic alterations that allow cancer cells to evade normal regulation and to finally colonize distant sites in the body. In this issue of The American Journal of Pathology, Petty et al report that expression of a relatively understudied protein called ...
openaire   +2 more sources

Vitamins as potent cancer treatments through regulating the activity and expression of MMP‐2 and MMP‐9

open access: yesBulletin of the Korean Chemical Society, Volume 47, Issue 6, Page 745-755, June 2026.
Vitamins could regulate both MMP‐2 and MMP‐9 expression and activity through transcriptional and MAPK signaling pathway modulation. This study highlights the potential of vitamins as low‐toxicity therapeutic or adjunct agents for targeting MMP‐mediated cancer progression. Abstract Matrix metalloproteinases (MMP‐2 and MMP‐9) are key regulators of cancer
Yen Thi Nguyen   +5 more
wiley   +1 more source

Gastric Cancer: Pathobiology and Therapeutics

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Gastric cancer is a multistep process driven by the interplay of microbial virulence, host epithelial injury, and evolving molecular reprogramming. Initiation involves pathogen‐induced epigenetic alterations and the early subversion of key oncogenic signaling networks, facilitating the transition from chronic injury to metaplasia and malignant ...
Ruixian Yu   +16 more
wiley   +1 more source

Vasculogenic mimicry and its clinical significance in medulloblastoma [PDF]

open access: yesCancer Biology & Therapy, 2012
Vasculogenic mimicry (VM), a process involving the formation of a tubular structure by highly invasive and genetically dysregulated tumor cells, can supplement the function of blood vessels to transport nutrients and oxygen to maintain the growth of tumor cells in many malignant tumors.
Shi-yong, Wang   +9 more
openaire   +2 more sources

VEGF and SEMA4D have synergistic effects on the promotion of angiogenesis in epithelial ovarian cancer

open access: yesCellular & Molecular Biology Letters, 2018
Background Anti-angiogenesis therapy that targets VEGF is one of the important treatment strategies in advanced ovarian cancer. However, depending on the pharmaceutical agent, treatment can have undesirable side effects.
Ying Chen   +3 more
doaj   +1 more source

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu   +6 more
wiley   +1 more source

Brucine inhibits vasculogenic mimicry of breast cancer cell lines in vitro and the related mechanism

open access: yesZhongguo aizheng zazhi, 2018
Background and purpose: The existence of vasculogenic mimicry (VM) in a large variety of highly invasive tumors, such as breast cancer, may lead to less effective traditional anti-angiotherapy.
索明珠
doaj  

The Tumor Immune Microenvironment in Endometrial Cancer: Composition, Molecular Subtypes, and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Endometrial cancer (EC), a major gynecologic malignancy and a representative “cold tumor”, exhibits a tumor immune microenvironment (TIME) influenced by a broad range of cellular and molecular elements, immunosuppressive signals, and pathways of immune evasion.
Jingxuan Ye   +4 more
wiley   +1 more source

Ocena roli badania zjawiska „mimikry naczyniowej” i gęstości mikronaczyń w nowotworach złośliwych jajnika u kobiet

open access: yesMenopause Review, 2011
Introduction: Neoplastic cells of various malignant tumours may induce formation of “vascular channels”which are not lined with endothelium. This phenomenon has been called “vasculogenic mimicry”.
Jarosław Daniłoś   +2 more
doaj  

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