Results 31 to 40 of about 25,819 (299)

Amide and Thioester Synthesis Via Oxidative Coupling of Alcohols with Amines or Thiols Using Alcohol Dehydrogenases

Angewandte Chemie, EarlyView.
Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Matteo Damian, Vasilis Tseliou, Patrick Peters, Tanja Knaus, Francesco G. Mutti   +4 more
wiley   +2 more sources

Dual‐Layer Living Hydrogel Enables On‐Demand Delivery of Phages and Probiotics for Synergistic Wound Infection Therapy

Advanced Functional Materials, EarlyView.
A dual‐layer living hydrogel, ProΦGel, integrates bacteriophages and probiotics for synergistic wound infection therapy. The outer gelatin‐based matrix releases phages on demand in response to P. aeruginosa infections, while inner alginate beads sustain probiotic delivery.
Siyuan Tao, Darine D'Adam, Anna Hu, Sixuan Zhang, Josua Roduner, Katharina Maniura‐Weber, Qun Ren   +6 more
wiley   +1 more source

Harnessing Photoenzymatic Systems for Intermolecular C–H Fluorination

Angewandte Chemie, EarlyView.
Despite the remarkable versatility of enzymes for catalyzing complex organic transformations under mild aqueous conditions, no biocatalytic system has been reported for intermolecular C–H fluorination. A radical photoenzymatic approach is introduced that leverages a designed de novo protein scaffold with an unnatural amino acid to achieve precise ...
Yu Zhou, Danielle Lawson, Zihan Zhang, Yunling Deng, Hejun Deng, Connor J. O'Dea, Zachariah A. Page, Yi Lu   +7 more
wiley   +2 more sources

High-Stakes Hormone: Vasopressin Use as a Last-Line Therapy for Shock in Pediatrics—A Narrative Review

Reports
Background and Clinical Significance: Shock in pediatric patients remains a leading cause of morbidity and mortality, with refractory cases posing significant challenges. While catecholamines like norepinephrine and epinephrine are standard vasopressors,
Marcin Sota, Daria Bramnik, Olivia Gudziewski, Ithamar Cheyne, Małgorzata Mikaszewska-Sokolewicz   +4 more
doaj   +1 more source

ELECTROENCEPHALOGRAPHIC AND BEHAVIORAL AROUSAL EFFECTS OF SMALL DOSES OF NICOTINE: A NEUROPSYCHOPHARMACOLOGICAL STUDY * [PDF]

, 1967
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75488/1/j.1749-6632.1967.tb13726.x ...
Domino, Edward F.
core   +1 more source

Injectable Dual‐Crosslinked Poly(oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Injectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...
Gurpreet Kaur Randhawa, Meghan Kostashuk, Zhicheng Pan, Nils Nordstrom, Thomas Kalab, Erica Winterhelt, Todd Hoare   +6 more
wiley   +1 more source

Anestésicos locales en odontoestomatología [PDF]

, 2004
El motivo del presente trabajo es hacer una revisión bibliográfica sobre los anestésicos locales (AL) que son las drogas de más uso en Odontoestomatología y que, merced a su perfeccionamiento, en los últimos años han significado un enorme avance, tanto ...
García-Pola Vallejo, M.J., Pipa Vallejo, A.   +1 more
core  

Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications

Advanced Materials, EarlyView.
Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa, Paolo Blesio, Marcial Fernandez‐Castro, Lisa Almonte, Maxence Fernandez, Mantas Liutkus, Perumal Pandurangan, Carlos Sabater, Aitor Villaverde, Manuel Melle‐Franco, Nurit Ashkenasy, Felipe Jiménez‐Ángeles, M. Carmen Morant‐Miñana, M. Reyes Calvo, Aitziber L. Cortajarena   +14 more
wiley   +1 more source

Effect of Vasopressin and Epinephrine in Cardiac Arrest Outcome in Patients with Asystole Rhythm

پزشکی بالینی ابن سینا, 2015
Introduction & Objective: The most persistent rhythm in the treatment of cardiac arrest is asys-tole. In this situation, the survival is rare. The choice is epinephrine, and vasopressin is as an alternative drug.
Mehdi Torabi
doaj  

Deep Breath Relaxation Training to Reduce Dysmenorrhoea Pain in Nursing Students, University of Muhammadiyah Gorontalo [PDF]

, 2021
Dysmenorrhoea is one of the most common gynecological problems affecting more than 50% of women and causes an inability to perform daily activities for 1 to 3 days each month. One of the management of pain during menstruation is by relaxing deep breaths,
Muhamad, Zuriati, Yunus, Pipin
core   +1 more source