Results 31 to 40 of about 25,503 (303)

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

open access: yesAdvanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen   +13 more
wiley   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

open access: yesAdvanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao   +9 more
wiley   +1 more source

Regioselective C─H Functionalization by the Combination of Enzymatic and Chemocatalytic Reactions in Water

open access: yesAngewandte Chemie, EarlyView.
H3CP contributes to sustainable synthesis by integrating regioselective enzymatic halogenation, Pd‐catalyzed Heck coupling, and enzymatic hydrolysis. TPGS‐705‐M micelles enable the Pd‐catalyzed step, allowing seamless compatibility with enzymatic reactions in one vessel under aqueous conditions.
Ran Zhu   +3 more
wiley   +2 more sources

Dynamics of calcitonin gene-related peptide-like cells changes in the lungs of two-kidney, one-clip rats [PDF]

open access: yes, 2012
Taking into consideration renal hypertension-induced homeostatic disorders and the key role of calcitonin gene-related peptide (CGRP) in many, systemic functions regulating systems, a question arises as to what an extent arterial hypertension affects the
Arciszewska, E., Kasacka, I.
core   +3 more sources

Self‐Sterilizing Face Mask Employing Enzymatic Power Generation

open access: yesAdvanced Materials Technologies, EarlyView.
Electric face mask with flexible biofuel cell integration for on‐the‐go sterilization is developed utilizing ethanol oxidation via alcohol dehydrogenase, and oxygen reduction via bilirubin oxidase. Modified face mask exhibited bacterial death rates of 40–60% at only 20 µA of electric current, easily generated by the biofuel cell continuously over hours
Daniella Marie Gatus   +3 more
wiley   +1 more source

Water‐Soluble Molecular Wires for Membrane Potential Imaging

open access: yesAngewandte Chemie, EarlyView.
Fully water‐soluble fluorescent rosamine‐based amphiphilic molecular wires were developed for imaging membrane potentials. The performance of the probes was evaluated in single cardiomyocytes, murine pituitary gland, and islets of Langerhans.
Mirna El Khatib   +9 more
wiley   +2 more sources

Anestésicos locales en odontoestomatología [PDF]

open access: yes, 2004
El motivo del presente trabajo es hacer una revisión bibliográfica sobre los anestésicos locales (AL) que son las drogas de más uso en Odontoestomatología y que, merced a su perfeccionamiento, en los últimos años han significado un enorme avance, tanto ...
García-Pola Vallejo, M.J.   +1 more
core  

Integrating Visible‐Light Photocatalysis and Enzymes for the Stereoselective Synthesis of Alcohols and Amines

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley   +1 more source

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

open access: yesAngewandte Chemie, EarlyView.
A highly stereoselective, dynamic reductive kinetic resolution (DYRKR) entry into myriad Taxotere‐like side chains with Clostridium acetobutylicum alcohol dehydrogenase (CaADH) enzyme is reported. Follow‐on cross couplings expand the structural diversity of the library (36 total examples).
Gaurav P. Kudalkar   +15 more
wiley   +2 more sources

Effect of Vasopressin and Epinephrine in Cardiac Arrest Outcome in Patients with Asystole Rhythm

open access: yesپزشکی بالینی ابن سینا, 2015
Introduction & Objective: The most persistent rhythm in the treatment of cardiac arrest is asys-tole. In this situation, the survival is rare. The choice is epinephrine, and vasopressin is as an alternative drug.
Mehdi Torabi
doaj  

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