Results 161 to 170 of about 9,347 (172)
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Mitochondrion, 2016
Hexokinase 2 (HK2) binds to Voltage-Dependent Anion Channel 1 (VDAC1) on mitochondrial outer membrane (MOM) to facilitate a preferential access of ATP to HK2 for glycolysis, in order to maintain a constant energy source for cell proliferation in cancer especially. While previous studies have discovered that the VDAC1 N-terminal helix is responsible for
Dawei, Zhang, Yew Mun, Yip, Liben, Li
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Hexokinase 2 (HK2) binds to Voltage-Dependent Anion Channel 1 (VDAC1) on mitochondrial outer membrane (MOM) to facilitate a preferential access of ATP to HK2 for glycolysis, in order to maintain a constant energy source for cell proliferation in cancer especially. While previous studies have discovered that the VDAC1 N-terminal helix is responsible for
Dawei, Zhang, Yew Mun, Yip, Liben, Li
openaire +2 more sources
Characterization of VDAC1 as a plasma membrane NADH‐oxidoreductase
BioFactors, 2004AbstractWe have recently demonstrated that voltage dependent anion selective channel 1 (porin, isoform 1) can function as a transplasma membrane NADH:ferricyanide‐reductase. However, both the specific redox characteristics and the mechanism of electron transport in this enzyme presently remain unclear.
Mark A, Baker +2 more
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Hypoxic VDAC1: A Potential Mitochondrial Marker for Cancer Therapy
2013Finding new therapeutic targets to fight cancer is an ongoing quest. Because of insufficiencies in tumor vasculature, cells often are exposed to a hostile microenvironment that is low in oxygen (hypoxic) and nutrients. Thus, tumor cells face the challenge of finding new sources of energy and defying apoptosis, which allow them to survive, grow, and ...
M Christiane, Brahimi-Horn, N M, Mazure
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Lipids influence the oligomeric organization of VDAC1
Biophysical JournalThe voltage-dependent anion channel (VDAC) is a mitochondrial outer membrane (MOM) β-barrel protein allowing passage of ions and metabolites (such as ATP, ADP, NADH⋯) in and out of the mitochondria. Besides its transport function, VDAC is implicated in mitochondrial regulation with roles in apoptosis, calcium homeostasis or neurodegeneration.
Lafargue, Elodie +5 more
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Oligomerization of the Mitochondrial Protein VDAC1
2013Varda Shoshan-Barmatz +2 more
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LDAO Solution for Purification of VDAC1 from Mitochondria
Cold Spring Harbor Protocols, 2013openaire +1 more source
Buffer G for Purification of VDAC1 from Mitochondria
Cold Spring Harbor Protocols, 2013openaire +1 more source
Buffer H for Purification of VDAC1 from Mitochondria
Cold Spring Harbor Protocols, 2013openaire +1 more source
Buffer I for Purification of VDAC1 from Mitochondria
Cold Spring Harbor Protocols, 2013openaire +1 more source