Results 91 to 100 of about 59,545 (218)

Metastable States in Two-Lane Traffic Flow Models With Slow-To-Start Rule [PDF]

open access: yes, 2006
Using computer simulations, we show that metastable states still occur in two-lane traffic models with slow to start rules. However, these metastable states no longer exist in systems where aggressive drivers (\textit{which do not look back before ...
Awazu   +11 more
core   +7 more sources

VDR in salivary gland homeostasis and cancer

open access: yesThe Journal of Steroid Biochemistry and Molecular Biology, 2020
The vitamin D receptor (VDR) and its ligand 1,25(OH)2D3 (1,25D) impact differentiation and exert anti-tumor effects in many tissues, but its role in salivary gland has yet to be defined. Using immunohistochemistry (IHC), we have detected strong VDR expression in murine and human salivary gland ducts. Compared to normal gland, VDR protein expression was
Kara A, DeSantis   +9 more
openaire   +3 more sources

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev   +5 more
wiley   +1 more source

Absence of vitamin D receptor (VDR)‐mediated PPARγ suppression causes alopecia in VDR‐null mice

open access: yesThe FASEB Journal, 2016
ABSTRACT Vitamin D receptor (VDR) mutations in humans and mice cause alopecia. VDR‐null (VDR −/− ) mice exhibit lack of postmorphogenic hair cycles as a result of impaired keratinocyte stem cell (KSC) function.
Vaibhav, Saini   +4 more
openaire   +3 more sources

European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) 2025 guidelines for surgical antimicrobial prophylaxis in dogs and cats

open access: yesJournal of Small Animal Practice, EarlyView.
Surgical antimicrobial prophylaxis involves the administration of antimicrobials to reduce the risk of a surgical site infection and represents a significant proportion of all antimicrobial use in cats and dogs. This evidence‐based, European Network for Optimization of Veterinary Antimicrobial Therapy guideline provides recommendations for both peri ...
F. Allerton   +21 more
wiley   +1 more source

Vitamin D Receptor Protects Against Dysbiosis and Tumorigenesis via the JAK/STAT Pathway in IntestineSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2020
Background & Aims: Vitamin D exerts regulatory roles via vitamin D receptor (VDR) in mucosal immunity, host defense, and inflammation involving host factors and microbiome.
Yong-Guo Zhang   +6 more
doaj   +1 more source

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

open access: yesObesity Reviews, EarlyView.
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley   +1 more source

Relationship between vitamin D deficiency and early implant failure and osseointegration

open access: yesPeriodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron   +8 more
wiley   +1 more source

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

open access: yesExperimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene   +4 more
wiley   +1 more source

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

open access: yesExperimental Physiology, EarlyView.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh   +6 more
wiley   +1 more source

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