Results 71 to 80 of about 12,305 (169)

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

open access: yesiNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang   +3 more
wiley   +1 more source

VDRE enrichment analysis of diffterentially expressed genes between Vdr-/- and Vdr+/+ placentae.

open access: yes, 2015
(A) Density of predicted VDR transcription factor binding sites in the sequence flanking transcription start sites (TSS) of genes differentially expressed between Vdr-/- and Vdr+/+ samples.
Shalem Leemaqz (762550)   +9 more
core   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik   +3 more
wiley   +1 more source

Production of recombinant human granulocyte‐macrophage colony‐stimulating factor in thermoinducible E. coli: Tuning inclusion body architecture and protein yield via dissolved oxygen control

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural characteristics, the impact of ...
Ximena Gómez‐Gil   +7 more
wiley   +1 more source

Patterns of psychopathology and personal strengths among youth in psychiatric care

open access: yesJCPP Advances, EarlyView.
Abstract Background The American Academy of Pediatrics and the American Academy of Child and Adolescent Psychiatry have declared a National State of Emergency in Children's Mental Health, calling for improved approaches to address youth mental health.
Logan R. Cummings   +78 more
wiley   +1 more source

VDR polymorphisms association with BMI scores.

open access: yes, 2014
Linear regression analyses were used to compare the VDR genotypes adjusted for the co-variants age and gender.
Abdul Khader Mohammed (597420)   +11 more
core   +1 more source

Ultra‐Fast and Energy‐Efficient PZT Optical Tunable Delay Lines for Programmable Photonic Systems

open access: yesLaser &Photonics Reviews, EarlyView.
Thin‐film PZT enables optical tunable delay lines that simultaneously offer sub‐nanosecond switching, low propagation loss, and zero‐static‐power programmability. A five‐bit on‐chip delay line provides a maximum delay of 387.5 ps with a resolution of 12.5 ps, while reconfigurable MZI splitting ratios further enable non‐volatile optical arbitrary ...
Cunyu Shi   +11 more
wiley   +1 more source

Portfolio effects of debt-equity swaps and debt exchanges with some applications to Latin America [PDF]

open access: yes
Voluntary debt reduction schemes (VDR), such as debt-equity swaps (DES) or collateralized debt conversions (CDC), are bound to play a relevant role in the foreign debt strategy of highly indebted countries (HICs). This paper assesses the impact of VDR on
Oks, Daniel
core  

Anticancer activity of VDR-coregulator inhibitor PS121912 [PDF]

open access: yes, 2014
PurposePS121912 has been developed as selective vitamin D receptor (VDR)-coregulator inhibitor starting from a high throughput screening campaign to identify new agents that modulate VDR without causing hypercalcemia. Initial antiproliferative effects of
Nishita D. Vyas   +29 more
core   +1 more source

Patterns of wild meat and other protein consumption in the periphery of Salonga National Park, Democratic Republic of the Congo

open access: yesPeople and Nature, EarlyView.
Abstract In Central Africa, human activities are severely impacting terrestrial and aquatic wildlife, threatening the food security of millions of people. Accordingly, sustainable use of wildlife is crucial for the nutrition and livelihoods of many rural communities in the region.
Zolo Admettons   +9 more
wiley   +1 more source

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