Results 51 to 60 of about 25,428 (209)

Vitamin D receptor prevents tumour development by regulating the Wnt/β-catenin signalling pathway in human colorectal cancer

open access: yesBMC Cancer, 2023
Background Colorectal cancer (CRC) is a common disease threatening human lives worldwide, and vitamin D receptor (VDR) contributes protective roles in this disease.
Jie Yu   +6 more
doaj   +1 more source

Novel N-Terminal Variant of Human VDR [PDF]

open access: yesMolecular Endocrinology, 2001
The importance of N-terminal regions of nuclear hormone receptors in transcriptional regulation is increasingly recognized. As variant VDR gene transcripts indicated possible N-terminally extended receptors, we investigated their natural occurrence, transactivation capacity, and subcellular localization. A novel 54-kDa VDRB1 protein, in addition to the
Sunn, K. L.   +4 more
openaire   +5 more sources

Patterns of psychopathology and personal strengths among youth in psychiatric care

open access: yesJCPP Advances, EarlyView.
Abstract Background The American Academy of Pediatrics and the American Academy of Child and Adolescent Psychiatry have declared a National State of Emergency in Children's Mental Health, calling for improved approaches to address youth mental health.
Logan R. Cummings   +78 more
wiley   +1 more source

Characterization of Rickets Type II Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor

open access: yesBiomolecules, 2023
Vitamin D has been known to exert a wide range of physiological effects, including calcemic, osteogenic, anticancer, and immune responses. We previously generated genetically modified (GM) rats and performed a comparative analysis of their physiological ...
Yuichiro Iwai   +10 more
doaj   +1 more source

Analysis of Climate Variability of Homogeneous Regions of Rainfall Anomalies in Southeast South America (SESA)

open access: yesInternational Journal of Climatology, EarlyView.
We studied rainfall variability and cyclicity in six Homogeneous Regions of Rainfall Anomalies (HRRA) in Southeast South America (SESA) from 1961 to 2020 to understand the occurrence of droughts and above‐average rainfall. We use a continental analysis scale, focusing on seasonal, interannual, and interdecadal cycles, and their association with modes ...
Tainã Costa Peres   +4 more
wiley   +1 more source

Vitamin D3: research breakthroughs and therapeutic use

open access: yesAnnals of Mechnikov's Institute, 2019
Vitamin D3 (cholecalciferol), the natural form of vitamin D, is produced in the skin from 7-dehydrocholesterol. The synthesis of vitamin D in the skin is the most important source of vitamin D.
М Pohorila   +6 more
doaj  

Population-genetic research of the VDR gene polymorphism

open access: yesФундаментальная и клиническая медицина, 2019
Aim. To explore the prevalence of alleles and genotypes in rsl544410 polymorphism within the VDR gene in the population of Kemerovo Region.Materials and Methods. Genotyping was performed in 232 residents of Kemerovo region (125 men and 107 women, average
A. N. Volkov, E. V. Tsurkan
doaj   +1 more source

Immunohistochemical expression of vitamin D receptor and forkhead box P3 in classic Hodgkin lymphoma: correlation with clinical and pathologic findings

open access: yesBMC Cancer, 2020
Background Expression of forkhead box P3 (FOXP3), a key regulator of T-cell function, in the tumor immune microenvironment is related to survival in classic Hodgkin lymphoma (CHL). Vitamin D receptor (VDR), a transcription factor agonists have been shown
Gaurav K. Gupta   +2 more
doaj   +1 more source

Ultra‐Fast and Energy‐Efficient PZT Optical Tunable Delay Lines for Programmable Photonic Systems

open access: yesLaser &Photonics Reviews, EarlyView.
Thin‐film PZT enables optical tunable delay lines that simultaneously offer sub‐nanosecond switching, low propagation loss, and zero‐static‐power programmability. A five‐bit on‐chip delay line provides a maximum delay of 387.5 ps with a resolution of 12.5 ps, while reconfigurable MZI splitting ratios further enable non‐volatile optical arbitrary ...
Cunyu Shi   +11 more
wiley   +1 more source

Patterns of wild meat and other protein consumption in the periphery of Salonga National Park, Democratic Republic of the Congo

open access: yesPeople and Nature, EarlyView.
Abstract In Central Africa, human activities are severely impacting terrestrial and aquatic wildlife, threatening the food security of millions of people. Accordingly, sustainable use of wildlife is crucial for the nutrition and livelihoods of many rural communities in the region.
Zolo Admettons   +9 more
wiley   +1 more source

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