Results 51 to 60 of about 25,277 (207)

Cultural Pathways to Sustainability: How Organizational Cultures Shape Firms' ESG Performance

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Understanding how organizational culture shapes firms' environmental, social, and governance (ESG) performance is essential for advancing effective sustainability management. Culture reflects shared values and norms that shape how firms enact ESG principles.
Marianna Delegach, Tal Katz‐Navon, Dana R. Vashdi   +2 more
wiley   +1 more source

Vitamin D receptor prevents tumour development by regulating the Wnt/β-catenin signalling pathway in human colorectal cancer

BMC Cancer, 2023
Background Colorectal cancer (CRC) is a common disease threatening human lives worldwide, and vitamin D receptor (VDR) contributes protective roles in this disease.
Jie Yu, Qi Sun, Yi Hui, Jinping Xu, Pancheng Shi, Yu Chen, Yunzhao Chen   +6 more
doaj   +1 more source

Characterization of Rickets Type II Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor

Biomolecules, 2023
Vitamin D has been known to exert a wide range of physiological effects, including calcemic, osteogenic, anticancer, and immune responses. We previously generated genetically modified (GM) rats and performed a comparative analysis of their physiological ...
Yuichiro Iwai, Ayano Iijima, Satoko Kise, Chika Nagao, Yuto Senda, Kana Yabu, Hiroki Mano, Miyu Nishikawa, Shinichi Ikushiro, Kaori Yasuda, Toshiyuki Sakaki   +10 more
doaj   +1 more source

PondNet – towards a global network of experiments on the effects of climate change on aquatic ecosystems

Ecography, EarlyView.
Global change is reshaping the distribution of biodiversity and the functioning of ecosystems. Predicting the long‐term consequences of such changes remains a challenge due to a need for a clear understanding of the mechanisms underpinning ecosystem‐level responses, as well as the role of geographical and environmental contingencies.
Miguel G. Matias, Dominique Gravel, Jonathan M. Chase, Carla Pinto‐ Cruz, David García‐ Callejas, M. Thomas P. Gilbert, Mathew A. Leibold, Dora Neto, Cátia L. Pereira, Carlos Ramos, Pedro M. Raposeiro, Alejandro Rozenfeld, Katarzyna Sroczynska, David R. Vieites, Guy Woodward, Miguel B. Araújo   +15 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Population-genetic research of the VDR gene polymorphism

Фундаментальная и клиническая медицина, 2019
Aim. To explore the prevalence of alleles and genotypes in rsl544410 polymorphism within the VDR gene in the population of Kemerovo Region.Materials and Methods. Genotyping was performed in 232 residents of Kemerovo region (125 men and 107 women, average
A. N. Volkov, E. V. Tsurkan
doaj   +1 more source

Immunohistochemical expression of vitamin D receptor and forkhead box P3 in classic Hodgkin lymphoma: correlation with clinical and pathologic findings

BMC Cancer, 2020
Background Expression of forkhead box P3 (FOXP3), a key regulator of T-cell function, in the tumor immune microenvironment is related to survival in classic Hodgkin lymphoma (CHL). Vitamin D receptor (VDR), a transcription factor agonists have been shown
Gaurav K. Gupta, Tanupriya Agrawal, Monika Pilichowska   +2 more
doaj   +1 more source

Effect of Zinc Oxide Nanoparticles From Infant Formula Milk Powder on Colon Cells In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Zinc is an essential trace element that participates in numerous metabolic processes; however, excessive exposure may interfere with the absorption of other metals, such as copper. In recent years, nanotechnology has experienced rapid growth, and zinc oxide nanoparticles (ZnO NPs) have garnered significant attention due to their versatile ...
Gloria Salinas‐Lucero, Karla Juarez‐Moreno, Rafael Vazquez‐Duhalt   +2 more
wiley   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Immunohistochemical Expression of Vitamin D Receptor (VDR) in Urinary Bladder Squamous Cell Carcinoma [PDF]

Türk Patoloji Dergisi
Objective: Squamous cell carcinoma (SCC) of the urinary bladder is associated with aggressive behavior and is typically treated with radical cystectomy.
Rehab MOHAMED SHARAF, Passant ESSAM ELDIN SHIBEL, Nadia Ahmed ABD EL-MOEZE   +2 more
doaj   +1 more source