Results 61 to 70 of about 12,305 (169)
Optical Control of the Glucocorticoid Receptor Activity With a Photoswitchable Agonist
Angewandte Chemie International Edition, EarlyView.A photoswitchable glucocorticoid receptor agonist enables optical control of receptor activity, achieving picomolar potency and partial agonism that preferentially maintains anti‐inflammatory signaling over canonical transcriptional activation. ABSTRACT Glucocorticoids (GCs) are widely prescribed anti‐inflammatory agents whose clinical utility is ...
Zoe Sessions +8 more
wiley +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.Abstract On the centennial of higher education in Chemical Engineering in Mexico, it is pertinent to revisit the key stages that have contributed to its consolidation as a vital discipline for the nation's scientific and technological advancement. Although the initial mission of chemical engineering education was primarily oriented toward the training ...
Agustín López Munguía +3 more
wiley +1 more source
Immunohistochemical Expression of Vitamin D Receptor (VDR) in Urinary Bladder Squamous Cell Carcinoma [PDF]
Türk Patoloji DergisiObjective: Squamous cell carcinoma (SCC) of the urinary bladder is associated with aggressive behavior and is typically treated with radical cystectomy.
Rehab MOHAMED SHARAF +2 more
doaj +1 more source
, 2018 Flow cytometry indicated that VDR overexpression increases caki-1 cell apoptosis, and VDR knockdown decreases caki-1 cell apoptosis. Graphs for each treatment group and the percentage of cell apoptosis are shown. X-axis: PL1-H Annexin V; Y-axis: PL2-H PI.
ShanFan Liao (5104922) +7 more
core +1 more source
Cultural Pathways to Sustainability: How Organizational Cultures Shape Firms' ESG Performance
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT Understanding how organizational culture shapes firms' environmental, social, and governance (ESG) performance is essential for advancing effective sustainability management. Culture reflects shared values and norms that shape how firms enact ESG principles.
Marianna Delegach +2 more
wiley +1 more source
SENPs facilitate deSUMOylation of VDR.
, 2014 Depicted are cell-based SUMOylation assays performed as described in materials and methods using the following experimental conditions: A. HEK-293 cells received expression constructs for V5-VDR, His-SUMO2 and UBC9 or parent control.
Peter W. Jurutka (525213) +9 more
core +1 more source
Microclimate mediates the strength and direction of avian biotic interactions
Ecography, EarlyView.Theory predicts that the strength and direction of species interactions can shift from being competitive in benign environments toward being facilitative in stressful environments. However, the environmental context dependency of species interactions has rarely been tested in animal communities.
Sarah J. K. Frey +6 more
wiley +1 more source
, 2019 Relative mRNA expression of VDR using stable reference gene GAPDH. Human myoblasts were isolated from subjects with either the CC- or TT-genotype for the VDR polymorphism TaqI rs731236 and were stimulated for 24-h in DMSO alone, 0.01nM, 1nM and 100nM 1 ...
Lina Ekström (6372611) +9 more
core +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Genes differentially expressed between Vdr-/- and Vdr+/+ placentae.
, 2015 Genes differentially expressed between Vdr-/- and Vdr+/+ placentae.
Shalem Leemaqz (762550) +9 more
core +1 more source