Results 61 to 70 of about 25,428 (209)

Immunohistochemical Expression of Vitamin D Receptor (VDR) in Urinary Bladder Squamous Cell Carcinoma [PDF]

open access: yesTürk Patoloji Dergisi
Objective: Squamous cell carcinoma (SCC) of the urinary bladder is associated with aggressive behavior and is typically treated with radical cystectomy.
Rehab MOHAMED SHARAF   +2 more
doaj   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong   +7 more
wiley   +1 more source

Large‐scale characterization of horizontal forest structure from remote sensing optical images

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Sub‐meter resolution remote sensing data and tree crown segmentation techniques hold promise in offering detailed information that can support the characterization of forest structure from a horizontal perspective, offering new insights in the tree crown structure at scale.
Xin Xu   +12 more
wiley   +1 more source

Penile intracavernosal injection of succinylcholine for laryngospasm management during hypospadias repair

open access: yesUroPrecision, EarlyView.
Abstract Background Laryngospasm is a serious anesthetic complication that can lead to acute airway obstruction and hypoxemia. Standard management involves deepening anesthesia and administering succinylcholine intravenously (IV) or intramuscularly (IM). However, if IV access is lost or IM drug delivery is too slow, alternative routes are required.
Diego R. Álvarez Vega   +6 more
wiley   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng   +3 more
wiley   +1 more source

Immunohistochemical evaluation of vitamin D receptor (VDR) expression in cutaneous melanoma tissues and four VDR gene polymorphisms

open access: yesCancer Biology & Medicine, 2017
Objective : Vitamin D receptor (VDR) mediates vitamin D activity. We examined whether VDR expression in excised melanoma tissues is associated with VDR gene (VDR) polymorphisms.Methods : We evaluated VDR protein expression (by monoclonal antibody ...
Francesco La Marra   +6 more
doaj   +1 more source

Evaluating ChatGPT's Reliability in Analyzing Facial Asymmetry: A Comparative Study With Human Evaluators Using Cross Sectional Static Images

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Facial asymmetry assessment is often subjective and time intensive, thus we aim to evaluate reliability of ChatGPT in analyzing facial asymmetry compared to human raters. Methods Thirty patients with unilateral facial paralysis who underwent facial reanimation surgery were included in this study.
Ali B. Jafar   +2 more
wiley   +1 more source

Genome‐wide association and interaction analysis for proliferative retinopathy in adults with type 2 diabetes born during famine: The DOLCE study in Ukraine

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina   +7 more
wiley   +1 more source

Prospects of multipurpose biomonitoring for fisheries assessment based on environmental nucleic acids

open access: yesJournal of Fish Biology, EarlyView.
Abstract Methods using environmental nucleic acids have become highly effective for monitoring aquatic biodiversity, with an array of suitable use cases, including metrics for fisheries assessment. Traditional methods for assessing fish populations often rely on invasive techniques with limited spatial and temporal coverage.
Ana Ramón‐Laca   +6 more
wiley   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

open access: yesJournal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang   +3 more
wiley   +1 more source

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