Results 81 to 90 of about 12,305 (169)

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Penile intracavernosal injection of succinylcholine for laryngospasm management during hypospadias repair

UroPrecision, EarlyView.
Abstract Background Laryngospasm is a serious anesthetic complication that can lead to acute airway obstruction and hypoxemia. Standard management involves deepening anesthesia and administering succinylcholine intravenously (IV) or intramuscularly (IM). However, if IV access is lost or IM drug delivery is too slow, alternative routes are required.
Diego R. Álvarez Vega, Mariela R. Martinez, Steven Friedman, Tehilla Adams, Jordan L. Mendelson, William Nguyen, Jordan S. Gitlin   +6 more
wiley   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Impact of FokI (rs2228570) and BglI (rs739837) polymorphisms in VDR gene on permanent tooth eruption: A cross-sectional study

Journal of Oral Biology and Craniofacial Research
Introduction: Genetic polymorphisms who disturb the mineral homeostasis during tooth development and eruption are candidate to clarify the molecular mechanisms involved in changes in the tooth eruption chronology.
Caio Luiz Bitencourt Reis, Kelem Cristina Cambraia Caproni Guerra, Mariane Carolina Faria Barbosa, Fabricio Fernandes Ferreira, Daniela Coelho de Lima, Raquel Assed Bezerra Segato, Ana Cláudia Pedreira de Almeida, Mirian Aiko Nakane Matsumoto, Flares Baratto Filho, Maria Angélica Hueb de Menezes, Erika Calvano Küchler, Daniela Silva Barroso de Oliveira   +11 more
doaj   +1 more source

Evaluating ChatGPT's Reliability in Analyzing Facial Asymmetry: A Comparative Study With Human Evaluators Using Cross Sectional Static Images

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Facial asymmetry assessment is often subjective and time intensive, thus we aim to evaluate reliability of ChatGPT in analyzing facial asymmetry compared to human raters. Methods Thirty patients with unilateral facial paralysis who underwent facial reanimation surgery were included in this study.
Ali B. Jafar, Malak Motair, Shahah Al Hajeri   +2 more
wiley   +1 more source

Otistik bozukluklu çocuk hastalarda VDR gen polimorfizmi, VDR gen ekspresyonu ve VDR geni promotor metilasyonunun araştırılması

, 2013
Yaygın gelişimsel bozukluklar (YGB) içinde sınıflandırılan Otistik Bozukluk (OB), yaşamın ilk yıllarında başlayan, sosyal beceri, sözel ve sözel olmayan iletişim, bilişsel gelişimde özgül gecikmeler ve sapmalar, tekrarlayacı ve basmakalıp davranışlarla ...
BURHAN BALTA
core  

VDR association with RXRα and PTP proteins.

, 2013
(A) Mitochondrial extracts from untreated HaCaT cells were immunoprecipitated with anti-VDR and anti-RXRα rabbit antibody and detection by western blotting was performed with anti-VDR or anti-RXRα biotinylated antibodies and with anti-VDAC rabbit ...
Michele Destefanis (275919), Francesca Silvagno (275916), Marco Consiglio (275917), Valentina Foglizzo (275918), Gianpiero Pescarmona (275920)   +4 more
core   +1 more source

Genome‐wide association and interaction analysis for proliferative retinopathy in adults with type 2 diabetes born during famine: The DOLCE study in Ukraine

Acta Ophthalmologica, EarlyView.
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina, Most Champa Begum, Xuan Tung Trinh, Turkuler Özgumus, Mikael Åkerlund, Peter Nilsson, Leticia Maria Spindola, Valeriya Lyssenko   +7 more
wiley   +1 more source

Methylation Status of Vitamin D Receptor Gene Promoter in Benign and Malignant Adrenal Tumors

International Journal of Endocrinology, 2015
We previously showed a decreased expression of vitamin D receptor (VDR) mRNA/protein in a small group of adrenocortical carcinoma (ACC) tissues, suggesting the loss of a protective role of VDR against malignant cell growth in this cancer type ...
Catia Pilon, Andrea Rebellato, Riccardo Urbanet, Vincenza Guzzardo, Rocco Cappellesso, Hironobu Sasano, Ambrogio Fassina, Francesco Fallo   +7 more
doaj   +1 more source

The VDR storage site in human platelets.

, 2013
(A) Platelets observation by electron microscopy revealed a well preserved cell structure and organization of intracellular granules. Sample was processed in absence of anti-VDR primary antibody.
Enrico De Vivo (367914), Valentina Gallo (95843), Francesca Silvagno (275916), Gianna Mazzucco (367918), Gianpiero Pescarmona (275920), Angelo Attanasio (367915)   +5 more
core   +1 more source