Results 31 to 40 of about 59,545 (218)
Bile acid dysmetabolism in inflammatory bowel diseases
Alʹmanah Kliničeskoj Mediciny, 2023 Aim: To summarize the state-of-the-art data on the molecular mechanisms of bile acid (BA) synthesis and absorption, their impaired absorption and receptor-dependent signaling, as well as on the effects of the gut microbiota on BA metabolism in ...
Daria A. Kuznetsova +2 more
doaj +1 more source
Vitamin D3 receptor is highly expressed in Hodgkin's lymphoma [PDF]
, 2012 Background: Hodkin s lymphoma is one of the most frequent lymphoma in western world. Despite an overall good prognosis some patients suffer relapsing tumors which are difficult to cure.
Benz, Alexander +2 more
core +2 more sources
Oncotarget, 2015 The active form of vitamin D, 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3; calcitriol], plays a key role in mineral and bone homeostasis, and exerts potent anti-inflammatory and anti-proliferative activities [1]. It is thus a potential pharmacological agent to treat various diseases, including autoimmune disorders, infections and cancer [1].
Laverny, Gilles, Metzger, Daniel
openaire +2 more sources
Diabetes, Metabolic Syndrome and Obesity, 2022 Wenjie Wen,1,2,* Bin Huang,1,2,* Shandong Ye1,2 1Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of University of Science and Technology of China (USTC), Department of Life Sciences and Medicine, University ...
Wen W, Huang B, Ye S
doaj
Changes in renal WT-1 expression preceding hypertension development [PDF]
, 2016 Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica +8 more
core +2 more sources
Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight [PDF]
, 2016 Despite clear associations between vitamin D deficiency and obesity and/or type 2 diabetes, a causal relationship is not established. Vitamin D receptors (VDRs) are found within multiple tissues, including the brain.
Arble, Deanna M. +9 more
core +4 more sources
The role of vitamin D in seasonal acute respiratory viral infections and COVID-19
Терапевтический архив, 2020 A link between vitamin D deficiency and susceptibility to infectious diseases was suggested over a hundred years ago. Epidemiological studies show a strong association between seasonal fluctuations in vitamin D levels and the incidence of various ...
E. A. Pigarova +4 more
doaj +1 more source
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2023 Introduction. Vitamin D deficiency may be a natural predictor of the onset of coronary heart disease (CHD) and myocardial infarction (MI) at a young age. The results of studies of the various variants association of the vitamin D receptor (VDR) gene with
O. A. Bercovich +8 more
doaj +1 more source
Controlling Polymer Capture and Translocation by Electrostatic Polymer-Pore Interactions [PDF]
, 2017 Polymer translocation experiments typically involve anionic polyelectrolytes such as DNA molecules driven through negatively charged nanopores. Quantitative modelling of polymer capture to the nanopore followed by translocation therefore necessitates the
Abramowitz M. +4 more
core +2 more sources
Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR-Dependent Translational Control of Synaptic Proteins. [PDF]
Adv Sci (Weinh)Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Ren P +9 more
europepmc +2 more sources