Results 41 to 50 of about 59,545 (218)

Association of vitamin D receptor gene fok1 polymorphism with bone health in Pakistani population

Journal of Biochemical and Clinical Genetics, 2020
Background: Osteoporosis is the bone disease characterized by demineralization of the bone. One of the most important genetic factors responsible for the osteoporosis is the vitamin D receptor (VDR) gene polymorphism.
Najam Farooq, Anwar Ullah, Abida Arshad, Navida Riaz, Jabar Zaman Khan, Sobia Tabassum, Muhammad Arshad Malik   +6 more
doaj   +1 more source

A simple and sensitive method to detect vitamin D receptor expression in various disease models using stool samples

Genes and Diseases, 2021
Vitamin D receptor (VDR) executes the main biological functions of its ligand vitamin D. VDR/vitamin D plays critical roles in regulating host immunity, maintaining barrier functions, and shaping gut microbiome.
Yong-guo Zhang, Yinglin Xia, Jun Sun
doaj   +1 more source

Very important pharmacogene summary for VDR [PDF]

Pharmacogenetics and Genomics, 2012
The vitamin D receptor (VDR) binds the active form of vitamin D (1,25-dihydroxyvitamin D3). It belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. The gene was cloned by Baker and colleagues in 1988 and maps to chromosome 12q13.11 [1].
Poon, Audrey H., Gong, Li, Brasch-Andersen, Charlotte, Litonjua, Augusto A., Raby, Benjamin, Hamid, Qutayba, Laprise, Catherine, Weiss, Scott, Altman, Russ B., Klein, Teri E.   +9 more
openaire   +4 more sources

Vitamin D enzymes (CYP27A1, CYP27B1 and CYP24A1) and receptor expression in non-melanoma skin cancer [PDF]

, 2019
No abstract available for this ...
Apostolopoulos, Vasso, Blatch, Gregory L, Dass, Crispin R, Nemazannikova, Natalie, Sinclair, Rodney   +4 more
core   +2 more sources

The Anti-Sepsis Effect of Isocorydine Screened from Guizhou Ethnic Medicine is Closely Related to Upregulation of Vitamin D Receptor Expression and Inhibition of NFκB p65 Translocation into the Nucleus

Journal of Inflammation Research, 2022
Jing Luo,1 Nuoyan Wang,1 Ling Hua,1 Fei Deng,1 Dan Liu,1 Jun Zhou,1 Yue Yuan,1 Fumin Ouyang,1 Xuemin Chen,1 Shujuan Long,1 Yasi Huang,1 Zhanxing Hu,2,3 Hong Zhou1 1Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International ...
Luo J, Wang N, Hua L, Deng F, Liu D, Zhou J, Yuan Y, Ouyang F, Chen X, Long S, Huang Y, Hu Z, Zhou H   +12 more
doaj  

Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic MiceSummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: Observational epidemiologic studies have associated vitamin D deficiency with cholestasis. We reported previously that activation of the vitamin D/vitamin D receptor (VDR) axis in cholangiocytes mitigates cholestatic liver injury ...
Zhijian Zheng, Jing Xie, Liman Ma, Zhiqing Hao, Weiwei Zhang, Lihua Li   +5 more
doaj   +1 more source

Vitamin D. a dynamic molecule. how relevant might the dynamism for a vitamin be [PDF]

, 2015
Cholecalciferol, the precursor of Vitamin D3, is a very old, highly conserved, molecule. Its presence is evident in non-mineralized 750 million-year-old living species, such as plankton.
Mazzaferro, Sandro, Pasquali, Marzia
core   +2 more sources

Quercetin Directly Interacts with Vitamin D Receptor (VDR): Structural Implication of VDR Activation by Quercetin [PDF]

Biomolecules & Therapeutics, 2016
The vitamin D receptor (VDR) is a member of the nuclear receptor (NR) superfamily. The VDR binds to active vitamin D3 metabolites, which stimulates downstream transduction signaling involved in various physiological activities such as calcium homeostasis, bone mineralization, and cell differentiation.
Lee, Ki-Young, Choi, Hye-Seung, Choi, Ho-Sung, Chung, Ka Young, Lee, Bong-Jin, Maeng, Han-Joo, Seo, Min-Duk   +6 more
openaire   +2 more sources

Krill oil, vitamin D and Lactobacillus reuteri cooperate to reduce gut inflammation [PDF]

, 2018
Current research into original therapies to treat intestinal inflammation is focusing on no-drug therapies. KLD is a mixture of krill oil (KO), probiotic Lactobacillus reuteri (LR), and vitamin D (VitD3).
Cesi, V., Colantoni, E., Costanzo, M., Cucchiara, S., Leter, B., Negroni, A., Palone, F., Pierdomenico, M., Stronati, L., Vitali, R.   +9 more
core   +1 more source

Vitamin D Receptor (VDR) mRNA and VDR Protein Levels in Relation to Vitamin D Status, Insulin Secretory Capacity, and VDR Genotype in Bangladeshi Asians [PDF]

Diabetes, 2002
Associations have been reported between vitamin D receptor (VDR) gene polymorphisms, type 1 diabetes, insulin secretion, and the insulin resistance syndrome. As VDR polymorphisms have no known functional significance, these findings may implicate a variant of the VDR gene or a locus in linkage disequilibrium with the VDR.
Babatunji-William, Ogunkolade, Barbara J, Boucher, Jean M, Prahl, Stephen A, Bustin, Jacky M, Burrin, Kate, Noonan, Bernard V, North, Nassima, Mannan, Michael F, McDermott, Hector F, DeLuca, Graham A, Hitman   +10 more
openaire   +2 more sources