Results 81 to 90 of about 59,545 (218)

Difference and similarity of DNA sequence recognized by VDR homodimer and VDR/RXR heterodimer

open access: yesNucleic Acids Research, 1994
Nuclear receptors for the thyroid hormone and vitamin A and D cooperate with the retinoid X receptor (RXR) in activating the transcription. Although the hormone response elements for these receptors have been proposed in which spacing of the direct repeated motifs determine the specificity (so called 3-4-5 rule), vitamin D response elements (VDREs) in ...
J, Nishikawa   +4 more
openaire   +3 more sources

Numerical analysis of the effects of corrosion on the punching shear capacity of reinforced concrete flat slabs with openings

open access: yesStructural Concrete, EarlyView.
Abstract The reinforcement corrosion is one of the main degradation mechanisms in reinforced concrete structures. Its effects can harm structural elements by reducing mechanical capacity, mainly due to diminished reinforcement properties and expansive reactions within the concrete.
Vinícius D'Almeida Rodrigues Ramos   +3 more
wiley   +1 more source

Vitamin D: Newer Concepts of Its Metabolism and Function at the Basic and Clinical Level. [PDF]

open access: yes, 2020
The interest in vitamin D continues unabated with thousands of publications contributing to a vast and growing literature each year. It is widely recognized that the vitamin D receptor (VDR) and the enzymes that metabolize vitamin D are found in many ...
Bikle, Daniel D
core   +1 more source

Analysis of the interaction of calcitriol with the disulfide isomerase ERp57 [PDF]

open access: yes, 2016
Calcitriol, the active form of vitamin D3, can regulate the gene expression through the binding to the nuclear receptor VDR, but it can also display nongenomic actions, acting through a membrane- associated receptor, which has been discovered as the ...
Altieri, Fabio   +7 more
core   +1 more source

A lack of standardization across urology fellowship program websites is hurting applicants

open access: yesUroPrecision, EarlyView.
Abstract Background As senior urology residents explore potential fellowship opportunities, they often turn to the official websites of accredited fellowship programs. However, the information available on these websites is often inconsistent and lacking. Methods The list of accredited fellowship programs on each subspecialty society's official website
Jordan L. Mendelson   +13 more
wiley   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng   +3 more
wiley   +1 more source

Plasma instability and amplification of electromagnetic waves in low-dimensional electron systems

open access: yes, 1998
A general electrodynamic theory of a grating coupled two dimensional electron system (2DES) is developed. The 2DES is treated quantum mechanically, the grating is considered as a periodic system of thin metal strips or as an array of quantum wires, and ...
A. B. Mikhailovskii   +34 more
core   +1 more source

VDR - the next generation

open access: yes, 2008
The European Maritime Data Management (EMDM) project faces the challenge of safe and secure European transport development with the study and development of new applications, functionalities and proposals for Voyage Data Recorders (VDRs) and Electronic Logbooks (ELBs).
Austin, S.   +3 more
openaire   +2 more sources

Hypoxia regulates Th17/Treg balance by altering chromatin accessibility and gene expression

open access: yesThe FEBS Journal, EarlyView.
T‐cell differentiation into Th17 or iTreg cells is key to inflammation control. Integrated RNA‐seq and ATAC‐seq analyses reveal that hypoxia induces more extensive gene expression changes in iTreg cells. Elevated levels of Hif1a and Stat3, along with increased accessibility to key transcription factor motifs, may predispose these cells toward ...
Mariana Cázares‐Olivera   +5 more
wiley   +1 more source

Ligand-associated activation of vitamin D receptors and potential points of application of its effects in the morphogenesis of immune inflammation: Literature review

open access: yesActa Biomedica Scientifica
According to recent data, vitamin D is classified as a substance with hormonal activity, which, in addition to classical, has “non-classical” effects caused by the complex relationship between vitamin D and effector cells of the immune system.
E. T. Ablyakimov, M. A. Kriventsov
doaj   +1 more source

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