Results 41 to 50 of about 182,452 (358)

International Network for Capacity Building for the Control of Emerging Viral Vector-Borne Zoonotic Diseases: Arbo-Zoonet [PDF]

, 2009
Arboviruses are arthropod-borne viruses, which include West Nile fever virus (WNFV), a mosquito-borne virus, Rift Valley fever virus (RVFV), a mosquito-borne virus, and Crimean-Congo haemorrhagic fever virus (CCHFV), a tick-borne virus.
Ahmed, J., Bouloy, M., Calistri, P., Chevalier, V., Drosten, C., Ergonul, O., Estrada-Pena, A., Fooks, A.R., Mirazimi, A., Moormann, R.J.M., Paweska, J., Seitzer, U., Tordo, N., Unger, H., Vatansever, Z., Yin, H.   +15 more
core  

Human behaviors: a threat for mosquito control?

, 2015
Community involvement and the preventive behavior of households are considered to be at the heart of vector-control strategies. In this work, we consider a simple theoretical model that enables us to take into account human behaviors that may interfere ...
Dumont, Y., Thuilliez, J.
core   +3 more sources

Canine vector-borne diseases in India: a review of the literature and identification of existing knowledge gaps [PDF]

, 2010
Despite the combination of favourable climate for parasites and vectors, and large populations of stray dogs, information concerning the epidemiology, diagnosis and management of canine vector-borne diseases in India is limited. However, with the country'
Puteri Azaziah Megat Abd Rani, Peter J Irwin, Mukulesh Gatne, Glen T Coleman, Rebecca J Traub   +4 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Evaluation of an Italian Phlebotomus perfiliewi (Larroussius) wild population as a permissive vector species for Leishmania tropica and L. major transmission

Parasites & Vectors
Background Among pathogenic Leishmania species, L. major and L. tropica, occur mainly in North African and Middle Eastern countries, primarily transmitted by Phlebotomus papatasi and P. sergenti respectively. In Italy, P.
Ilaria Bernardini, Claudia Mangiapelo, Eleonora Fiorentino, Stefania Orsini, Riccardo Bianchi, Anna Rosa Sannella, Aldo Scalone, Trentina Di Muccio, Gioia Bongiorno   +8 more
doaj   +1 more source

Canine tick-borne pathogens in Cyprus and a unique canine case of multiple co-infections [PDF]

, 2017
Canine tick-borne pathogens such as Ehrlichia canis and Hepatozoon canis are widespread in the Mediterranean basin but have never been reported or investigated in Cyprus.
Altschul, Baneth, Barker, Chalker, Chochlakis, Chochlakis, Christodoulou, Dantas-Torres, Dawson, Demaerschalck, Di Loria, Inokuma, Ioannou, Ioannou, Le Riche, Matjila, Mazeris, Mekuzas, Mylonakis, Mylonakis, Novacco, Oosthuizen, Parola, Psaroulaki, Psaroulaki, Robinson, Sainz, Solano-Gallego, Tamura   +28 more
core   +4 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Estimated density of Borrelia burgdorferi sensu stricto-infected Ixodes scapularis nymphs in the eastern United States

Parasites & Vectors
Background Most vector-borne disease cases reported in the United States are caused by pathogens spread by blacklegged ticks, Ixodes scapularis. Of these, a majority are Lyme disease cases caused by Borrelia burgdorferi sensu stricto (s.s.). Because most
Karen M. Holcomb, Erik Foster, Sarah E. Maes, Christina M. Parise, Lynn M. Osikowicz, Andrias Hojgaard, Rebecca J. Eisen   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Evaluation of an interferon-gamma release assay for early detection of lumpy skin disease virus infection and vaccination in cattle

Microbiology Spectrum
Lumpy skin disease virus (LSDV) causes a nodular dermatitis in cattle and has high economic consequences in affected areas. Detection of LSDV exposure mostly relies on the humoral immune response, while the cell-mediated immune (CMI) response, an ...
Nina Kresic, Wannes Philips, Andy Haegeman, Nick de Regge   +3 more
doaj   +1 more source