Results 81 to 90 of about 182,452 (358)

Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges

Advanced Functional Materials, EarlyView.
Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley   +1 more source

Culex tarsalis is a competent vector species for Cache Valley virus [PDF]

, 2018
Background: Cache Valley virus (CVV) is a mosquito-borne orthobunyavirus endemic in North America. The virus is an important agricultural pathogen leading to abortion and embryonic lethality in ruminant species, especially sheep.
Alto, Barry W., Ayers, Victoria B., Blitvich, Bradley J., Dunlop, James I., Higgs, Stephen, Huang, Yan-Jang, Kohl, Alain, Lyons, Amy C., Park, So Lee, Unlu, Isik, Vanlandingham, Dana L.   +10 more
core   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

Advanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch, Sandra Kessler, Simone Ponta, Anna Puiggalí‐Jou, Guoliang Lyu, Killian Flégeau, Anastasiya Martyts, Florian Roth, David Fercher, Filippo M. Rijli, Daniel Simmen, Eva Novoa Olivares, Thomas Linder, Marcy Zenobi‐Wong   +13 more
wiley   +1 more source

Insecticidal efficacy of residual spraying with deltamethrin–clothianidin (Fludora® Fusion) in Papua New Guinea

Parasites & Vectors
Background In Papua New Guinea (PNG), insecticide-treated nets leave considerable gaps in protection from Anopheles mosquito bites and, as a result, malaria cases are increasing.
Evodia Anetul, Petrina Johnson, Rebecca Vinit, Nakei Bubun, Kiari Kiari, Rowena Absalom, Daniel Aulim, Paul Daly, Melanie Koinari, Tiziano Raffaelli, Jason H. Richardson, Michael Macdonald, Jacob Kisomb, Maria Ome-Kaius, Moses Laman, Leanne J. Robinson, Stephan Karl   +16 more
doaj   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Prion replication in organotypic brain slice cultures is distinct from in vivo inoculation and is species dependent

Acta Neuropathologica Communications
Cultured brain slices rapidly replicate murine prions, exhibit prion pathology, and are amenable towards drug discovery, but have not been infected with human prions.
Jessy A. Slota, Lise Lamoureux, Jennifer Myskiw, Kathy L. Frost, Sarah J. Medina, Dominic M. S. Kielich, Melanie Leonhardt, Gunjan Thapar, Ben A. Bailey-Elkin, Stephanie A. Booth   +9 more
doaj   +1 more source

The dynamics of questing ticks collected for 164 consecutive months off the vegetation of two landscape zones in the Kruger National Park (1988–2002). Part III. The less commonly collected species

Onderstepoort Journal of Veterinary Research, 2011
Despite many studies regarding tick ecology, limited information on long-term changes in tick populations exist. This study assessed the long-term population dynamics of the less frequently collected questing ixodid ticks in the Kruger National Park ...
Gordon J. Gallivan, Andrea Spickett, Heloise Heyne, Arthur M. Spickett, Ivan G. Horak   +4 more
doaj   +1 more source

Zika virus and the never-ending story of emerging pathogens and transfusion medicine [PDF]

, 2016
In the last few years, the transfusion medicine community has been paying special attention to emerging vector-borne diseases transmitted by arboviruses.
Grazzini, Giuliano, Liumbruno, Giancarlo M, Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +4 more
core   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source