Results 101 to 110 of about 2,059,233 (272)

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

Advanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu, Yanfei Sun, Yuehua Zhu, Guangjing Mu, Jiazheng Wang, Liangliang Wang, Feihu Zhao, Zhimin Zhao, Jian Wang, Ying He, Zheng Jiang, Xingang Li, Mingzhi Han, Bin Huang   +13 more
wiley   +1 more source

NEVBD Quarterly Digest Issue 4 [PDF]

, 2019
The Northeast Regional Center for Excellence in Vector-Borne Diseases is supported through Cooperative Agreement Number 1U01CK000509-01 between the Centers for Disease Control and Prevention (CDC) and Cornell UniversityThe Northeast Regional Center for ...
Northeast Regional Center for Excellence in Vector-Borne Diseases
core   +2 more sources

Looking for Dog Blood Donors in an Endemic Area for Vector-Borne Infections of Central Italy. [PDF]

Animals (Basel), 2022
Antognoni MT, Vascellari M, Da Rold G, Toniolo F, Sgubin S, Zanardello C, Carminato A, Miglio A.   +7 more
europepmc   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Emerging zoonoses and vector-borne infections affecting humans in Europe

Epidemiology and Infection, 2007
SUMMARYThe purpose of this study was to assess and describe the current spectrum of emerging zoonoses between 2000 and 2006 in European countries. A computerized search of the Medline database from January 1966 to August 2006 for all zoonotic agents in European countries was performed using specific criteria for emergence.
Vorou, R. M., Papavassiliou, V. G., Tsiodras, S.   +2 more
openaire   +4 more sources

Serological Survey of Canine Vector-Borne Infections in North-Center Spain. [PDF]

Front Vet Sci, 2021
Pérez Pérez P, Rodríguez-Escolar I, Carretón E, Sánchez Agudo JÁ, Lorenzo-Morales J, Montoya-Alonso JA, Morchón R.   +6 more
europepmc   +1 more source

NEVBD Quarterly Digest Issue 5 [PDF]

, 2019
The Northeast Regional Center for Excellence in Vector-Borne Diseases is supported through Cooperative Agreement Number 1U01CK000509-01 between the Centers for Disease Control and Prevention (CDC) and Cornell UniversityThe Northeast Regional Center for ...
Northeast Regional Center for Excellence in Vector-Borne Diseases
core   +2 more sources

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Research approaches in the development of interventions against vector-borne infection [PDF]

Journal of Experimental Biology, 2003
SUMMARYThe conceptual basis of public health entomology developed at the turn of the twentieth century with the seminal experiments that guided the first vector-directed interventions. Within 50 years, technological advances built confidence in the power of research to resolve threats posed by vector-borne pathogens.
openaire   +2 more sources

DETECTION OF VECTOR-BORNE INFECTIONS IN LIONS AND TIGERS AT TWO ZOOS IN TENNESSEE AND OKLAHOMA, USA. [PDF]

J Zoo Wildl Med, 2022
Cerreta AJ, Yang TS, Ramsay EC, Birkenheuer AJ, Rahoi D, Qurollo B, Wilson J, Cushing AC.   +7 more
europepmc   +1 more source