Results 81 to 90 of about 70,893 (253)

CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors

Advanced Science, EarlyView.
Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen, Xiaoyun Luo, Huixin Gao, Yujing Ke, Yu Zhan, Xiaoting Xu, Xiaoxiao Xiong, Fengjiao Wei, Si Yang, Zhonghua Liu, Bolan Yu, Zhaofeng Huang, Yingjie Bian   +12 more
wiley   +1 more source

Contributions of ENDOBACT multicentric study to the infective endocarditis etiology in Romania

Romanian Journal of Laboratory Medicine, 2013
Studiul multicentric ENDOBACT a avut ca scop implementarea metodelor moleculare de identificare a speciilor bacteriene implicate in endocardita infecţioasă, precum şi încercarea de a diminua numărul cazurilor cu etiologie neprecizată.
Oprea Mihaela, Surdeanu Maria, Badescu Daniela, Cotar Ani Ioana, Dinu Sorin, Banu Otilia, Flonta Mirela, Straut Monica   +7 more
doaj   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

Epidemiological Situation on Vector-Borne Natural-Focal Infections in the Territory of Caucasian Mineral Waters

Проблемы особо опасных инфекций, 2014
Represented is the analysis of epidemiological situation on vector-borne natural-focal infections in the specially protected eco-resort territory of Russia - Caucasian Mineral Waters of the Stavropol Region.
N. F. Vasilenko, A. V. Ermakov, O. V. Maletskaya, A. N. Kulichenko   +3 more
doaj   +1 more source

Case report: Substantial improvement of autism spectrum disorder in a child with learning disabilities in conjunction with treatment for poly-microbial vector borne infections. [PDF]

Front Psychiatry, 2023
Offutt A, Breitschwerdt EB.
europepmc   +1 more source

WNV infection - an emergent vector borne viral infection in Serbia: Current situation

Veterinarski glasnik, 2015
West Nile virus (WNV) is a neurovirulent mosquito-borne Flavivirus with zoonotic potential. Virus is maintained in nature in an enzootic transmission cycle between avian hosts and mosquito vectors, but occasionally infects other vertebrates.
Tamas Petrovic, Diana Lupulovic, Dusan Petric, Ana Vasic, Ivana Hrnjakovic-Cvjetkovic, Vesna Milosevic, Dejan Vidanovic, Milanko Sekler, Sava Lazic, Bosiljka Djuricic, Budimir Plavsic, Juan-Carlos Saiz   +11 more
openaire   +3 more sources

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Human tick biting and tick-borne disease risk in Türkiye: Systematic review.

PLoS Neglected Tropical Diseases
Ticks serve as significant vectors for over 100 pathogens, many of which pose serious health risks to humans. Türkiye's diverse tick species and ideal ecological conditions facilitate their proliferation.
Salar Zarrabi Ahrabi, Fatihan Pınarlık, Gürkan Akyıldız, Mert Kuşkucu, Sırrı Kar, Önder Ergönül, Ayşen Gargılı Keleş, TEH Vector-Borne Infections Study Group   +7 more
doaj   +1 more source

Chronological change in the incidence risk levels of mosquito-borne and rodent-borne infections

International Journal of Infectious Diseases
Introduction: We examined the change over time in the incidence risk levels of mosquito-borne and rodent-borne infections. Methods: We used the data of “Summary of risk assessment of vector-borne disease at Japanese Quarantine ports and airports ...
Dr Soichi Takeishi, Dr Tatsuo Inoue, Dr Koichi Miyamura   +2 more
doaj   +1 more source

Haematological Alterations Associated with Selected Vector-Borne Infections and Exposure in Dogs from Pereira, Risaralda, Colombia. [PDF]

Animals (Basel), 2022
Bonilla-Aldana DK, Gutiérrez-Grajales EJ, Osorio-Navia D, Chacón-Peña M, Trejos-Mendoza AE, Pérez-Vargas S, Valencia-Mejía L, Marín-Arboleda LF, Martínez-Hidalgo JP, Reina-Mora MA, González-Colonia LV, Cardona-Ospina JA, Jiménez-Posada EV, Diaz-Guio DA, Salazar JC, Sierra M, Muñoz-Lara F, Zambrano LI, Ramírez-Vallejo E, Álvarez JC, Jaramillo-Delgado IL, Pecho-Silva S, Paniz-Mondolfi A, Faccini-Martínez ÁA, Rodríguez-Morales AJ.   +24 more
europepmc   +1 more source