Results 31 to 40 of about 21,465 (238)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Representação em Bond Graphs de motores Brushless DC e inverosres de frequência [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Automação e Sistemas, Florianópolis, 2013.Este trabalho apresenta a construção de um modelo computacional para estudo do ...
Simão, Renato Ferreira
core
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Morphotronics and Bond Graphs Representation [PDF]
Bond Graphs theory can assist in tracking power movements in a system that is defined by effort and flow variables. An electronic circuit uses the network where flow (current) moves when affected by the effort (voltage).
Resconi, G +3 more
core +1 more source
LFT Bond Graph for Online Robust Fault Detection and Isolation of Hybrid Multi-Source System [PDF]
International audienceAbstract Green hydrogen is undoubtedly the most promising energy vector of the future because it is captured by renewable and inexhaustible sources, such as wind and/or solar energy, and can be stored over the long in high-pressure ...
Radi, Youness +8 more
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
A bond graph representation of an optimal control problem: the example of the DC motor [PDF]
International audienceOptimization has become of great importance in present day Systems Engineering. Also, bond graph language proves to be a very efficient tool for modelling, analysing and designing mechatronic systems from an energy and dynamic point
Marquis-Favre, Wilfrid +3 more
core +3 more sources
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

