ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Improved Purification and Quantitative Kinetics Monitoring of <i>Triatoma virus</i> Infection of <i>Rhodnius prolixus</i>. [PDF]
Gutiérrez-Millán E +3 more
europepmc +1 more source
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
Outbreaks and incidence of vector-borne diseases in Colombia (2007-2024): Impact of climate change and deforestation [PDF]
Olivera MJ +2 more
europepmc +1 more source
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong +10 more
wiley +1 more source
No time to wait: A regional model for inter-epidemic vector-borne disease preparedness in the Caribbean. [PDF]
Dunbar W +8 more
europepmc +1 more source
Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu +4 more
wiley +1 more source
Repellency of Eucalyptol and DEET Against <i>Triatoma infestans</i>, a Chagas Disease Vector: A Proof-of-Concept Study Under a Human Odor Background. [PDF]
Wagner LS, Guerenstein PG.
europepmc +1 more source
Objective Studies of damage accrual in patients with systemic lupus erythematosus (SLE) show associations with disease activity measured by the SLE Disease Activity Index 2000 (SLEDAI‐2K), but these associations are imperfect. SLEDAI scores are powerfully influenced by weightings (1–8) assigned to each domain.
Kevin Zhang +8 more
wiley +1 more source
Histological and Lectinhistochemical Pattern of the Inflammatory Response to <i>Ascocotyle</i> sp. Metacercariae in <i>Mugil liza</i> Hearts. [PDF]
Di Cesare L +4 more
europepmc +1 more source

