N-VEGF, the autoregulatory arm of VEGF-A [PDF]
Cells, 2021 Vascular endothelial growth factor A (VEGF-A) is a secreted protein that stimulates angiogenesis in response to hypoxia. Under hypoxic conditions, a non-canonical long isoform called L-VEGF is concomitantly expressed with VEGF-A. Once translated, L-VEGF it is proteolytically cleaved to generate N-VEGF and VEGF-A. Interestingly, while VEGF-A is secreted
Marina Katsman +4 more
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Comprehensive assessment of the dynamics of angiogenesis in patients with psoriasis treated with methotrexate [PDF]
Vestnik Dermatologii i Venerologii, 2023 Background. Evaluation of the severity of pathological angiogenesis in patients with psoriasis can be considered as a promising direction for monitoring the activity of the disease and the effectiveness of systemic therapy. Aims.
Olga A. Pritulo, Alexey A. Petrov
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Evaluation of effect of epidermal growth factor receptor and vascular endothelial growth factor overexpression in survival of patients with glioblastoma multiforme [PDF]
Romanian Journal of Neurology, 2021 Background. In the central nervous system, glioblastoma multiforme (GBM) is one of the most important neoplasms in adults. Amplification of EGFR and VEGF genes is common in GBM. However, the role of overexpression of EGFR and VEGF in survival of patients
Babak Alijani +5 more
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Induction of humoral immune responses and inhibition of metastasis in mice by a VEGF peptide-based vaccine [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Blocking of vascular endothelial growth factor (VEGF) plays a pivotal role in inhibition of metastasis and is a target for development of anti-angiogenic agents.
Faezeh Soltanpour Gharibdousti +6 more
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The Effects of VEGF Signal Pathway on Etiopathogenesis and AntiVEGF Treatments in Childhood Cancers
Çocuk Dergisi, 2023 Vascular endothelial growth factor (VEGF) is the most physiologically and pathologically potent angiogenic factor that acts directly on endothelial cells.
Ali Kazdal +3 more
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Correlation of Vascular and Inflammatory Index in Oral Pyogenic Granuloma and Periapical Granuloma – An Insight into Pathogenesis [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Angiogenesis is vital in the aetiology and pathogenesis of a number of pathological processes that include solid reactive lesions like pyogenic granuloma and chronic inflammatory disorders like periapical granuloma. Vascular Endothelial
Joy Thomas Vara +5 more
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Quantitative expression of VEGF, VEGF-R1, VEGF-R2, and VEGF-R3 in melanoma tissue microarrays [PDF]
Human Pathology, 2010 Angiogenesis is required for progression and metastasis of melanoma. Analysis of angiogenic molecules in benign and malignant tissues may allow identification of markers useful for prediction of sensitivity to antiangiogenic agents. We hypothesized that differential expression of vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, VEGF-
Janice M, Mehnert +7 more
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Regenerative Medicine and Angiogenesis; Focused on Cardiovascular Disease [PDF]
Advanced Pharmaceutical Bulletin, 2022 Cardiovascular disease (CVD) is a major concern for health with high mortality rates around the world. CVD is often associated with partial or full occlusion of the blood vessel network.
Seyed Zachariah Moradi +3 more
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Indian Journal of Ophthalmology, 2021 Purpose: Identification of nonresponders prior to anti-vascular endothelial growth factor (anti-VEGF) therapy would help in the judicious clinical management of diabetic macular edema (DME) patients.
Tessy Xavier +5 more
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Engineered microenvironments for synergistic VEGF - integrin signalling during vascularization [PDF]
, 2017 We have engineered polymer-based microenvironments that promote vasculogenesis both in vitro and in vivo through synergistic integrin-growth factor receptor signalling. Poly(ethyl acrylate) (PEA) triggers spontaneous organization of fibronectin (FN) into
Cantini, Marco +9 more
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