Results 91 to 100 of about 413,657 (289)
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti +4 more
wiley +1 more source
Emmanuele De Luca,1,2,* Donatella Marino,1,2,* Massimo Di Maio1,2 1Department of Oncology, University of Turin, Torino, Italy; 2Division of Medical Oncology, Ordine Mauriziano Hospital, Torino, Italy*These authors contributed equally to this ...
De Luca E, Marino D, Di Maio M
doaj
Growth Promoting Effect of Vacuum Sealing Drainage in the Healing Processes of Diabetic Foot Ulcers
Hui Yang,* Lan Liu,* Gai Li, Yinchen Chen, Dong Jiang, Wei Wang, Tianyuan Wang, Jinshan Sun, Jianfang Che, Dongmei Gu, Meng Lu, Aiping Wang Department of Endocrinology, The Air Force Hospital from Eastern Theater of PLA, Nanjing 210029, People’s ...
Yang H +11 more
doaj
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source
Objetivos. Esta investigación tiene como objetivo estudiar los efectores inmunológicos que se inducen en los pacientes inmunizados con el CIGB-247, que incluyen elementos humo - rales y celulares.
Javier Sánchez Ramírez +11 more
doaj
Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
Study of biomarkers p53, Ki-67, Bcl-2, and VEGF in pterygium
Purpose: To study the biomarkers present in primary pterygium samples of patients of Indian ethnicity and compare it with the samples obtained from the unaffected conjunctiva of the same eye.
Shilpa Ghosh +4 more
doaj +1 more source
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
VEGF-A splicing patterns in kidney tissue obtained from healthy mice and humans.
The VEGF-A 121, 165, and 189 isoforms were measured in kidney biopsies obtained from healthy human subjects, and the corresponding VEGF-A isoforms (VEGF-A 120, 164, and 188, respectively) were measured in kidney tissue and obtained from healthy mice ...
H. J. Baelde (3105789) +4 more
core +1 more source
Modern aspects of the pathogenesis, diagnosis and treatment of diabetic retinopathy
The article discusses current ideas about the pathogenesis, risk factors, and new methods of diagnosis and treatment of diabetic retinopathy. This disease is a specific microvascular ocular complication of diabetes mellitus and is part of the group of ...
Elmaz Z. Kayalieva +2 more
doaj +1 more source

