Results 101 to 110 of about 482,957 (287)
???????????????????? ???????????????????? ?? ?????????????????????? ?????????????????????????????? ?????????????? ?????????? (VEGF) ?? ?????????????? ?????????????????? ?? ?????????????????????? ?????? [PDF]
, 2019 This paper presents the results of the study of serum levels of melatonin and VEGF with various severity of psoriasis and with sleep disorder and without it. The study revealed significant increase of VEGF levels and decrease of serum levels of melatonin with maximum deviation in severe disease.
openaire +3 more sources
Advanced Materials, EarlyView.Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma +15 more
wiley +1 more source
Modern aspects of the pathogenesis, diagnosis and treatment of diabetic retinopathy
Клинический разбор в общей медицинеThe article discusses current ideas about the pathogenesis, risk factors, and new methods of diagnosis and treatment of diabetic retinopathy. This disease is a specific microvascular ocular complication of diabetes mellitus and is part of the group of ...
Elmaz Z. Kayalieva +2 more
doaj +1 more source
Drug Design, Development and Therapy, 2016 As a progressive chronic disease, age-related macular degeneration (AMD) is the leading cause of irreversible vision impairment worldwide. Experimental and clinical evidence has demonstrated that vascular endothelial growth factor (VEGF) plays a vital ...
Shiqi Yang, Jingke Zhao, Xiaodong Sun
semanticscholar +1 more source
Advanced Materials Technologies, EarlyView.Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le +4 more
wiley +1 more source
Advanced Science, EarlyView.IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source
Advanced Science, EarlyView.Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
wiley +1 more source
Targeting VEGF and its Receptors for the Treatment of Osteoarthritis and Associated Pain
Journal of Bone and Mineral Research, 2016 Increased vascular endothelial growth factor (VEGF) levels are associated with osteoarthritis (OA) progression. Indeed, VEGF appears to be involved in OA‐specific pathologies including cartilage degeneration, osteophyte formation, subchondral bone cysts ...
J. Hamilton +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer +17 more
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2023 Lisa Andriani Lienggonegoro,* Frans Dany,* Novaria Sari Dewi Panjaitan* Center for Biomedical Research, Research Organization for Health, National Research and Innovation Agency (BRIN), Cibinong Science Center, Cibinong, West Java, Indonesia ...
Lienggonegoro LA, Dany F, Panjaitan NSD
doaj