Results 161 to 170 of about 2,650,230 (376)

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

Tranexamic Acid Inhibits Angiogenesis and Melanogenesis in Vitro by Targeting VEGF Receptors. [PDF]

Int J Med Sci, 2020
Zhu JW, Ni YJ, Tong XY, Guo X, Wu XP, Lu ZF.   +5 more
europepmc   +1 more source

Supplementary Figure 1 from Dual HER/VEGF Receptor Targeting Inhibits <i>In Vivo</i> Ovarian Cancer Tumor Growth [PDF]

, 2023
Marc A. Becker, Thahir Farzan, Sean C. Harrington, James Krempski, S. John Weroha, Xiaonan Hou, Kimberly R. Kalli, Tai W. Wong, Paul Haluska   +8 more
openalex   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema.

Journal of Clinical Investigation, 2000
Y. Kasahara, R. Tuder, L. Taraseviciene‐Stewart, T. L. Cras, S. Abman, P. Hirth, J. Waltenberger, N. Voelkel   +7 more
semanticscholar   +1 more source

SKLB1002, a potent inhibitor of VEGF receptor 2 signaling, inhibits endothelial angiogenic function in�vitro and ocular angiogenesis in�vivo

, 2020
Qiuyang Zhang, Tao Shu-Ya, Lu Chang, Jingjing Li, Xiu‐Miao Li, Jin Yao, Qin Jiang, Biao Yan   +7 more
openalex   +2 more sources

A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation [PDF]

, 2015
Yang Shen, Lin Zeng, Ruslan Novosyadlyy, Amélie Forest, Aiping Zhu, Andrew I. Korytko, Haifan Zhang, Scott W. Eastman, Michael Topper, Sagit Hindi, Nicole Covino, Kris Persaud, Yun Kang, Douglas Burtrum, David Surguladze, Marie Prewett, Sudhakar Chintharlapalli, Victor J. Wroblewski, Juqun Shen, Paul Balderes, Zhenping Zhu, M D Snavely, Dale L. Ludwig   +22 more
openalex   +1 more source

Cystathionine β-synthase as novel endogenous regulator of lymphangiogenesis via modulating VEGF receptor 2 and 3 [PDF]

, 2022
Niloofar Hatami, Christian Büttner, Felix Bock, Sara Simfors, Gwen Musial, André Reis, Claus Cursiefen, Thomas Clahsen   +7 more
openalex   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source