Results 11 to 20 of about 2,608,192 (371)
The presence of VEGF receptors on the luminal surface of endothelial cells affects VEGF distribution and VEGF signaling. [PDF]
PLoS Computational Biology, 2009 Vascular endothelial growth factor (VEGF) is a potent cytokine that binds to specific receptors on the endothelial cells lining blood vessels. The signaling cascade triggered eventually leads to the formation of new capillaries, a process called ...
Marianne O Stefanini +3 more
doaj +5 more sources
Zebrafish VEGF receptors: a guideline to nomenclature. [PDF]
PLoS Genetics, 2008 In placental mammals (eutherians), there exist three paralogous genes of the vascular endothelial growth factor (VEGF) receptor family, namely FLT1 (also named VEGFR1), KDR (also named FLK1 and VEGFR2), and FLT4 (also named VEGFR3).
Jeroen Bussmann +4 more
doaj +8 more sources
A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis. [PDF]
Nat Commun, 2017 Non-classical secretory vesicles, collectively referred to as extracellular vesicles (EVs), have been implicated in different aspects of cancer cell survival and metastasis.
Feng Q +8 more
europepmc +2 more sources
PLoS ONE, 2013 Vascular endothelial growth factor (VEGF) is up-regulated during mesothelial to mesenchymal transition (MMT) and has been associated with peritoneal membrane dysfunction in peritoneal dialysis (PD) patients.
María Luisa Pérez-Lozano +9 more
doaj +2 more sources
Fox(y) regulators of VEGF receptors. [PDF]
Circ Res, 2014 Vascular development is a multistep process that initially involves vasculogenesis, the process of de novo formation of the primitive vasculature from mesodermal precursors, and angiogenesis, that involves sprouting and remodeling of the primitive vasculature.1 This is followed by vascular fate specification steps that define formation of arterial ...
Ricard N, Simons M.
europepmc +5 more sources
The impact of high density receptor clusters on VEGF signaling [PDF]
Electronic Proceedings in Theoretical Computer Science, 2013 Vascular endothelial growth factor (VEGF) signaling is involved in the process of blood vessel development and maintenance. Signaling is initiated by binding of the bivalent VEGF ligand to the membrane-bound receptors (VEGFR), which in turn stimulates ...
Ye Chen +3 more
doaj +4 more sources
Structure and function of VEGF receptors
IUBMB Life, 2009 AbstractVascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel development and homeostasis. VEGFs are predominantly produced by endothelial, hematopoietic, and stromal cells in response to hypoxia and upon stimulation by growth factors such as transforming growth factor β (TGFβ), interleukins, or platelet‐derived growth factors
E. Stuttfeld, K. Ballmer-Hofer
semanticscholar +4 more sources
VEGF, its receptors and the Tie receptors in recurrent miscarriage [PDF]
Molecular Human Reproduction, 2000 The aetiology of recurrent miscarriage (at least three consecutive miscarriages) usually remains unsolved. The vascular endothelial growth factor (VEGF) family of proteins, together with their receptors and the Tie (tyrosine kinase with immunoglobulin and epidermal growth factor homology domains) receptors, are crucial for embryonic development ...
Erja Halmesmäki +3 more
openaire +4 more sources
The role of VEGF receptors in angiogenesis; complex partnerships [PDF]
Cellular and Molecular Life Sciences, 2006 .Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel development and homeostasis but also have profound effects on neural cells.
Stéphanie Cébe-Suarez +2 more
semanticscholar +4 more sources
VEGF Receptor Signaling in Tumor Angiogenesis [PDF]
The Oncologist, 2000 Abstract The growth of human tumors and development of metastases depend on the de novo formation of blood vessels. The formation of new blood vessels is tightly regulated by specific growth factors that target receptor tyrosine kinases (RTKs).
Gerald McMahon
openaire +4 more sources