The impact of high density receptor clusters on VEGF signaling [PDF]
Electronic Proceedings in Theoretical Computer Science, 2013 Vascular endothelial growth factor (VEGF) signaling is involved in the process of blood vessel development and maintenance. Signaling is initiated by binding of the bivalent VEGF ligand to the membrane-bound receptors (VEGFR), which in turn stimulates ...
Ye Chen +3 more
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Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. [PDF]
Journal of Clinical Investigation, 1993 Dorit Shweiki +4 more
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Impact of ligand binding on VEGFR1, VEGFR2, and NRP1 localization in human endothelial cells. [PDF]
PLoS Computational BiologyThe vascular endothelial growth factor receptors (VEGFRs) bind to cognate ligands to facilitate signaling pathways critical for angiogenesis, the growth of new capillaries from existing vasculature. Intracellular trafficking regulates the availability of
Sarvenaz Sarabipour +6 more
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Comparative in silico Survey of Retinoic Acids as Putative Biomolecules Against VEGF Receptors: A Glycomics-based Approach [PDF]
Journal of Cell and Molecular Research, 2021 In this study, putative interactions between all of the retinoic acid (RA) ligands (all-trans (At), 9-cis (9c), and 13-cis (13c)), and VEGF receptors (VEGFR-1, -2 and -3) were investigated.
Ali Fallah +3 more
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An Investigation of Vascular Endothelial Growth Factor (VEGFR-1 and VEGFR-2) in Burn Wound Healing [PDF]
Archives of Razi Institute, 2022 Burn damage is a complicated trauma that causes local and general tissue edema as a result of cell breakage and capillary leak syndrome. Angiogenesis plays a key part in the mechanisms that are initiated by tissue damage (e.g., burns) since it works ...
L Abdulazeem, A Tariq, Saade Jasim
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Nephrotoxicity induced by vascular endothelial growth factor inhibitors [PDF]
Journal of Nephropharmacology, 2022 Vascular endothelial growth factor (VEGF) is a special mitogen for vascular endothelial cells, an essential endogenous angiogenic cytokine, and the principal controller of vascular growth that plays a fundamental role in therapeutic angiogenesis pathways.
Shirinsadat Badri +5 more
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Specific dynamics in vascular endothelial growth factors (VEGF) in blood of patients with vitamin D-resistant rickets during correction of multiplanar deformities of lower limbs [PDF]
Гений oртопедии, 2020 Background Vitamin D-resistant rickets is a systemic disease with impaired bone remodeling that interferes with orthopaedic treatment of musculoskeletal pathologies.
Nikita S. Gvozdev +5 more
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The immunohistochemical landscape of the VEGF family and its receptors in glioblastomas
Surgical and Experimental Pathology, 2020 Background Angiogenesis is one of the hallmarks of cancer. This complex mechanism of tumor progression provides tumors cells with essential nutrients. There have been a limited number of investigations of markers of angiogenesis in Glioblastomas (GBMs ...
Luiz Victor Maia Loureiro +5 more
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VEGF and its receptors - formation, structure, and role in the organism
Journal of Education, Health and Sport, 2023 Creating vessels is essential for the development of every organism and the course of repair processes. Under physiological conditions, angiogenesis is a transient and tightly regulated process.
Krzysztof Olczyk +3 more
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Mechanism of selective VEGF-A binding by neuropilin-1 reveals a basis for specific ligand inhibition. [PDF]
PLoS ONE, 2012 Neuropilin (Nrp) receptors function as essential cell surface receptors for the Vascular Endothelial Growth Factor (VEGF) family of proangiogenic cytokines and the semaphorin 3 (Sema3) family of axon guidance molecules. There are two Nrp homologues, Nrp1
Matthew W Parker +3 more
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