Results 191 to 200 of about 29,745,998 (266)

Prognostic significance and relationship of SMAD3 phospho-isoforms and VEGFR-1 in gastric cancer: A clinicopathological study. [PDF]

World J Gastrointest Oncol
Lv SL, Guo P, Zou JR, Chen RS, Luo LY, Huang DQ.   +5 more
europepmc   +1 more source

COL1A1+ Epithelial Cells Orchestrate VEGFA‐VEGFR Signaling in Endometritis Revealed by Single‐Cell Analysis

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley   +1 more source

Heparan Sulfate Proteoglycans: Master Regulators of Cellular Signaling, Tissue Development, and Neural Function

Journal of Neuroscience Research, Volume 104, Issue 9, September 2026.
Ubiquitous cell‐associated, cytoplasmic, synaptic and extracellular matrix HS‐proteoglycans are multifunctional regulators of tissue form and function. HS‐proteoglycans have diverse functions as growth factor co‐receptors in cell proliferation, differentiation, tissue development, mechanical stabilization, synaptogenesis, synaptic plasticity, and ...
James Melrose
wiley   +1 more source

PRDM1 Knockdown Promotes Ferroptosis and Sunitinib Sensitivity by Modulating the PI3K/Akt Signaling Through Inhibition of ESM1 Transcription in Renal Cell Carcinoma

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 9, September 2026.
ABSTRACT Renal cell carcinoma (RCC) is a commonly occurring and considerable burden on public health. Although chemotherapy benefits patients with advanced RCC, sunitinib resistance leads to a poor prognosis. Ferroptosis is also involved in sunitinib resistance in RCC.
Yi‐Shuai Zhang, Xin‐Qi Pei, Ji‐Ping Sun, Chen‐Hui Ma, Xin‐Yang Wang, Xu‐Dong Li   +5 more
wiley   +1 more source

The Health Benefits of Exercise: Molecular and Cellular Mechanisms

MedComm, Volume 7, Issue 9, September 2026.
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying, Huilin Wang, Xiu Lu, Wenjuan Zhang, Zhehao Lin, Kai Wang, Shangxuan Li, Lu Chen, Mingchao Jiang, Sarkawt Hamad, Yi Wang, Jianmin Wu, Shukuan Ling   +12 more
wiley   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang, Jiangbo Fan, Wenyi Liu, Di Liu, Rui Wang, Yuanyang Wang, Jianhui Sun, Huacai Zhang, Qingli Cai, Zhe Xu, Fang Xu, Jianxin Jiang, Zhen Wang, Ling Zeng   +13 more
wiley   +1 more source

Blood Vessel Patterning on Retinal Astrocytes Requires Endothelial Flt-1 (VEGFR-1). [PDF]

J Dev Biol, 2019
Chappell JC, Darden J, Payne LB, Fink K, Bautch VL.   +4 more
europepmc   +1 more source

MRI‐based radiomics model for predicting VEGFA expression and prognosis in lower‐grade glioma

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Background Gliomas are the most common primary tumors of the central nervous system. Their treatment remains highly challenging, with high rates of associated disability and mortality. Conventional prognostic indicators no longer adequately satisfy the clinical demands of precision medicine.
Kun Zhao, Xinyu Hong, Hongrong Cheng, Shoucheng Xu, Dongliang Zhao, Jianyang Lin, Yongbing Gu, Guoqiang Ren, Baomin Chen, Liping Zhan, Yuanwei Wang   +10 more
wiley   +1 more source

Roadmap for the implementation of particle minibeam therapy

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Particle minibeam therapy (PMBT) has emerged as an advanced modality within spatially fractionated radiation therapy, using the physical properties of protons, ions, and electrons to achieve superior normal tissue sparing whilst preserving spatial dose distribution at depths that are unachievable in conventional kV or MV X‐rays.
Reem Ahmad, Oxana Actis, Adam H. Aitkenhead, Richard A. Amos, Niels Bassler, Catherine Burne, Pankaj Chaudhary, Gerd Datzmann, Umberto Deut, Fabio Di Martino, Rebecca Habgood, Simon Jolly, Emmanuel Jouglar, Eva Kasanda, Nigel Lee, Dominic Leiser, Xiangkun Li, Giuliana Milluzzo, Jessica Neubauer, Kelvin Ng Wei Siang, Hugo Palmans, Yolanda Prezado, Judith Reindl, Francesco Romano, Loris Roncali, Aikaterini Rousseti, Thomas E. Schmid, Ileana Silvestre Patallo, Frank Stephan, Anna Subiel, Edward Taylor, Annalisa Walpen, Samuel Flynn   +32 more
wiley   +1 more source

Molecular Mechanisms and Therapeutic Applications of Extracellular Vesicles in Remodeling of the Skin Cancer Niche

Nano Select, Volume 7, Issue 9, September 2026.
Extracellular vesicles at the nexus of skin cancer progression and precision therapy. EVs orchestrate tumor microenvironment remodeling through cargo‐mediated intercellular communication, immune modulation, angiogenesis, and extracellular matrix reorganization, while also emerging as next‐generation platforms for targeted drug delivery, biomarker ...
Megha Kotian, Maria Nison, Deepanjan Datta, Soniya Kumbham, Namdev Dhas, Praveen Halagali, Vasudev R Pai, Vamshi Krishna Tippavajhala   +7 more
wiley   +1 more source