Results 211 to 220 of about 29,745,998 (266)

Advances in therapeutic approaches to gastric cancer

CA: A Cancer Journal for Clinicians, Volume 76, Issue 5, September/October 2026.
Abstract Gastric cancer remains a leading cause of cancer‐related mortality worldwide, with nearly 1 million new cases diagnosed annually. Despite innovations in diagnosis, most patients still present at advanced stages, contributing to a poor prognosis.
Feng Wang, Zi‐Xian Wang, Yu‐Jing Zhang, Ye He, Jia‐Fu Ji, Yuan‐Fang Li, Xiu‐Juan Qu, Yi Ba, Shu‐Qiang Yuan, Rui‐Hua Xu   +9 more
wiley   +1 more source

Design, Synthesis, In Vitro Biological Evaluation, and In Silico Studies of Novel Imidazo[4,5-b]Pyridine-Acrylonitrile-Based Derivatives as VEGFR-2 Inhibitors Against Breast Cancer and Hepatocellular Carcinoma. [PDF]

Drug Dev Res
Mohamed LW, Saadeldin AA, Farag AB.
europepmc   +1 more source

Exceptional therapeutic benefit of imatinib in cKIT‐mutated mucosal melanoma followed by a KIT mutation loss

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 9, Page 1311-1313, September 2026.
Hannah Zillikens, Corinna Scheib, Vicky Peller, Christina Müller, Sebastian Bauer, Ina Pretzell, Klaus Griewank, Antje Sucker, Eva Hadaschik, Felicitas Guntrum, Sven Holger Baum, Alexander Roesch, Selma Ugurel, Dirk Schadendorf, Lisa Zimmer, Elisabeth Livingstone   +15 more
wiley   +1 more source

Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases. [PDF]

Oncotarget, 2019
Alvarez-Palomo B, Barrot-Feixat C, Sarret H, Requena J, Pau M, Vidal-Taboada JM, Oliva R, Ballesca JL, Edel MJ, Mezquita-Pla J.   +9 more
europepmc   +1 more source

1-Butylindoline-2,3-dione derivatives as potent VEGFR-2 inhibitors: synthesis, mechanistic anticancer studies, and molecular dynamics simulations. [PDF]

RSC Adv
El-Naggar M, Abdelaal HI, Albakri ME, Binjubair FA, Al-Rashood ST, Bouajila J, Fares M, Abdel-Aziz HA, Fakhry MM, Elkotamy MS.   +9 more
europepmc   +1 more source

New Chromene Derivatives as Promising VEGFR-2 Inhibitors: Experimental Cytotoxicity and Comprehensive Computational Characterization. [PDF]

Arch Pharm (Weinheim)
Elkady H, Alsfouk AA, Elkaeed EB, Elgammal WE, Mahdy HA, Nofal A, Eissa IH, Husein DZ, Amin FG, Metwaly AM.   +9 more
europepmc   +1 more source

A signal sequence multi-leucine motif regulates VEGF receptor signaling. [PDF]

J Biol Chem
Ghim M, Wei L, Jung JJ, The E, Kukreja G, Neishabouri A, Ahmad AA, Raza MZ, Golbazi A, Hedayatyanfard K, Nie L, Zhang Z, Wang L, Zhang J, Sadeghi MM.   +14 more
europepmc   +1 more source

Integrated design, synthesis, biological evaluation, and computational mechanistic insights of novel benzanilide derivatives as VEGFR-2 targeted anticancer agents. [PDF]

RSC Adv
Metwaly AM, Elgammal WE, Eissa IH, Mahdy HA, Taghour MS, Alsfouk AA, Amin FG, Husein DZ, Elkaeed EB, Elkady H.   +9 more
europepmc   +1 more source

Farnesyl Transferase Inhibitor KO-2806 (Darlifarnib) Enhances the Antitumor Activity of Tyrosine Kinase Inhibitors in RCC. [PDF]

Mol Cancer Ther
Gasendo JG, Chan S, Patel HV, Smith AE, Kessler L, Liu YA, Mitra A, Burrows F, Malik S.   +8 more
europepmc   +1 more source

Radioiodine-Refractory Differentiated Thyroid Cancer: Definition, Molecular Mechanisms, and Advances in Precision Therapy. [PDF]

Cancer Innov
Li Y, He Z.
europepmc   +1 more source