Results 211 to 220 of about 21,287,561 (278)

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu   +6 more
wiley   +1 more source

Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley   +1 more source

Synthesis, Photophysical Characterization, and Anticancer Evaluation of Novel Furochromene Derivatives

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
This is the first study on novel furochromene derivatives. A series of novel furochromen derivatives, namely (2E)‐1‐(6‐hydroxy‐4,7‐dimethoxy‐1‐benzofuran‐5‐yl)‐3‐arylprop‐2‐en‐1‐ones 4a–c, were synthesized via the Knoevenagel condensation of 6‐hydroxy‐4,7‐dimethoxybenzofuran‐5‐ylethanone 2 with various aromatic aldehydes.
Amal Rabahi   +9 more
wiley   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

open access: yesPediatric Investigation, Volume 10, Issue 3, Page 269-280, June 2026.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian   +5 more
wiley   +1 more source

Severe Thrombocytopenia Is Associated With Bleeding in Hepatocellular Carcinoma Patients Receiving Antiangiogenic Therapy

open access: yesPortal Hypertension &Cirrhosis, Volume 5, Issue 2, Page 140-149, June 2026.
Thrombocytopenia is common in hepatocellular carcinoma and may increase bleeding risk during antiangiogenic therapy, yet the clinically relevant platelet threshold remains uncertain. We found that a baseline platelet count < 50 × 109/L was associated with bleeding; patients below this cutoff had a substantially higher bleeding rate than those with ...
Jun Tie   +8 more
wiley   +1 more source

A new perspective on radiotherapy in the comprehensive treatment of cancer

open access: yesPrecision Radiation Oncology, Volume 10, Issue 2, Page 165-183, June 2026.
Radiotherapy remains a key component in the comprehensive management of cancer. Its effectiveness is significantly improved through strategic combinations with chemotherapy, targeted therapy, and immunotherapy, providing a range of therapeutic outcomes from cure to palliative care.
Yingze Ma   +4 more
wiley   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini   +7 more
wiley   +1 more source

Natural Monoterpene Stylosin Induced Anticancer Effects on Human Colon Carcinoma Cells

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Extraction of STL from Ferula ovina by TLC and structural confirmation by 1H NMR. Favorable pharmacokinetics. Reduced CRC cell viability in a time‐ and dose‐dependent manner. Induced apoptosis. Interacted with the active site of HGFR. ABSTRACT Colorectal carcinoma (CRC) ranks among the top five most common malignancies globally, characterized by a high
Sara Seyedshazileh   +3 more
wiley   +1 more source

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