Results 81 to 90 of about 24,477,013 (226)
UVA promoted tyrosine phosphorylation of VEGFR-1 and VEGFR-2 in normal human keratinocytes.
, 2013 (a) The time-dependent phosphorylation of VEGFR-1 and VEGFR-2 in keratinocytes induced by 10 J/cm2 UVA. Cells were harvested 0, 2, 4, 8, 12, 24 h after irradiation. (b) The densitometric analysis of (a).
Zhong-Fa Lu (285979) +5 more
core +1 more source
Precisely Engineering Biomimetic Nanoparticles via Controlled Cell Membrane Coating
Small, EarlyView.Precise engineering of cell membrane‐coated nanoparticles (CMNPs) requires coordinated control over particle size, coating integrity, and membrane leaflet orientation. This review integrates key synthesis parameters, assembly strategies, and analytical methods that govern these features, revealing how structural control underpins biomimetic function ...
Jie Lay Lim +4 more
wiley +1 more source
Chemistry Central Journal, 2017 Background Tumor angiogenesis, essential for tumor growth and metastasis, is tightly regulated by VEGF/VEGFR and PDGF/PDGFR pathways, and therefore blocking those pathways is a promising therapeutic target.
Ting-Hsuan Yang +3 more
doaj +1 more source
Biomarkers to predict outcomes in diabetic foot ulcers
VIEW, EarlyView.Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro +6 more
wiley +1 more source
Medicine in Drug Discovery, 2019 New blood vessels formation from the existing vasculature is called angiogenesis. It is an essential physiological process for the growth of cells, tissue repair, wound healing, and reproductive system of females.
Siddharth J. Modi, Vithal M. Kulkarni
doaj +1 more source
VEGFR-3 directly interacts with PI3K to regulate lymphangiogenesis
, 2012 VEGFR-3 directly interacts with PI3K to regulate ...
Elizabeth D Williams (19147639) +3 more
core
Renal ischemia-reperfusion increases endothelial VEGFR-2 without increasing VEGF or VEGFR-1 expression [PDF]
, 2002 Renal ischemia-reperfusion increases endothelial VEGFR-2 without increasing VEGF or VEGFR-1 expression.BackgroundHypoxia is a potent stimulus to angiogenesis.
Stacker, Steven A. +6 more
core +1 more source
Andrology, EarlyView.ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source