Results 71 to 80 of about 698,039 (294)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
, 2001 Traffic flow at low densities (free traffic) is characterized by a quasi-one-dimensional relation between traffic flow and vehicle density, while no such fundamental diagram exists for `synchronized' congested traffic flow.
Banks +28 more
core +2 more sources
ActuatorsThis study introduces a computational framework that formalizes rollover risk in heavy-duty vehicles by integrating simulation-informed physical modeling with sensor-driven decision logic.
Farshad Afshari, Daniel Garcia-Pozuelo
doaj +1 more source
An Analytical Study of Fire Out of Battery Using Magneto Rheological Dampers
Shock and Vibration, 2002 The application of magneto rheological dampers for controlling the dynamics of a fire out-of-battery recoil system is examined, using a dynamic simulation of a 105mm cannon. Upon providing a brief background on MR dampers and fire out-of-battery dynamics,
Mehdi Ahmadian +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Fast Simulation of Vehicles with Non-deformable Tracks
, 2017 This paper presents a novel technique that allows for both computationally fast and sufficiently plausible simulation of vehicles with non-deformable tracks. The method is based on an effect we have called Contact Surface Motion.
Pecka, Martin +2 more
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Creation of acoustic vortex knots
Nature Communications, 2020 Although knots in complex optical fields have been realized experimentally, the realization of acoustic vortex knots is still problematic. Here, the authors have demonstrated the creation of acoustic vortex knots by embedding the knot function into a ...
Hongkuan Zhang +6 more
doaj +1 more source
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source
ActuatorsThrough this paper, an active disturbance rejection control scheme is designed based on an extended state observer capable of estimating the system’s internal variables and external disturbances without the need for expensive sensors and also attenuates ...
Carlos Saralegui Esteve +2 more
doaj +1 more source