Results 61 to 70 of about 3,339,018 (306)
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Instants and Instantaneous Velocity [PDF]
This paper will argue that the puzzles about instantaneous velocity, and rates of change more generally, are the result of a failure to recognize an ambiguity in the concept of an instant, and therefore of an instantaneous state.
James Harrington, Harrington, James
core
Ray Trace Tomographic Velocity Analysis of Surface Seismic Reflection Data [PDF]
Recent development of two technologies allows application of a generalized formulation of travel time inversion to very large data sets, such as the surface reflection surveys collected for oil exploration.
Stork, Christof
core +1 more source
Velocity Estimation of Moving Target Based on Two-dimensional Projection for LFM UWB Radar
Two-Dimensional (2D) projection in temporal-Doppler plan is utilized to solve the effects of range-Doppler coupling and Doppler dispersion on radial velocity estimation for Linear Frequency Modulation (LFM) Ultra-WideBand (UWB) radar.
Yang Li-min +3 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Failure mechanism and structure optimization of masonry building due to debris flow impact
:Flood and debris flow are the main contributor of mountain hazards in China. Along these years, due to the space limitation, buildings, which are the main element at risk, are mostly located at debris flow alluvial fan.
leiyu
doaj
Trajectory Planning of Robotic Arm Based on Particle Swarm Optimization Algorithm
Achieving vibration-free smooth motion of industrial robotic arms in a short period is an important research topic. Existing path planning algorithms often sacrifice smoothness in pursuit of efficient motion.
Nengkai Wu +3 more
doaj +1 more source
Turbulence Measurements with Dual-Doppler Scanning Lidars
Velocity-component variances can be directly computed from lidar measurements using information of the second-order statistics within the lidar probe volume.
Alfredo Peña, Jakob Mann
doaj +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
PIV Experimental Research and Numerical Simulation of the Pigging Process
The initial running speed of the pig during gas–liquid two-phase pipeline pigging can significantly influence the velocities of both gas and liquid phases within the pipeline.
Shengtao Chen +3 more
doaj +1 more source

