Chronic hepatitis in horses with persistent equine hepacivirus infection
Abstract Background Equine hepacivirus (EqHV) is closely related to hepatitis C virus (HCV), which causes persistent infection and chronic hepatitis in people. Information on persistent EqHV infection and hepatitis is limited. Objectives To report 19 cases of chronic hepatitis and persistent EqHV infection.
Mason C. Jager +13 more
wiley +1 more source
Sofosbuvir/velpatasvir regimen promises an effective pan-genotypic hepatitis C virus cure
Fazia Mir, Alp S Kahveci, Jamal A Ibdah, Veysel Tahan Division of Gastroenterology and Hepatology, University of Missouri, Columbia, MO, USA Abstract: Hepatitis C virus (HCV) is a global pandemic, with nearly 200 million infected patients worldwide ...
Mir F, Kahveci AS, Ibdah JA, Tahan V
doaj
Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR [PDF]
The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who ...
Berenguer, Juan +14 more
core +5 more sources
Profile of sofosbuvir/velpatasvir/voxilaprevir in the treatment of hepatitis C
Lindsey M Childs-Kean, Natalie A Brumwell, Emma F LodlDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL, USAAbstract: The treatment of chronic hepatitis C has been revolutionized with the
Childs-Kean LM, Brumwell NA, Lodl EF
doaj
Objective To identify potential drug interactions (DIs) between pangenotypic direct-acting antivirals (pDAAs) and concomitant cardiovascular (CV) therapies in patients with chronic hepatitis C (CHC).
Antoni Sicras-Mainar +1 more
doaj +1 more source
Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells
SARS coronavirus 2 (SARS-CoV-2) has caused an ongoing global pandemic with significant mortality and morbidity. At this time, the only FDA-approved therapeutic for COVID-19 is remdesivir, a broad-spectrum antiviral nucleoside analog.
Xammy Huu Wrynla +22 more
doaj +1 more source
Evolución de los pacientes infectados por el virus de la hepatitis C tratados con antivirales de acción directa en Álava. Durante el período 2015-2017. [PDF]
[ES] La infección por el virus de la hepatitis C (VHC) en la población general se caracteriza por una evolución crónica y, en general, benigna, tal como demuestran los estudios epidemiológicos prospectivos y retrospectivos.
Gil González, Cristina
core
Projections of the healthcare costs and disease burden due to hepatitis C infection under different treatment policies in Malaysia, 2018-2040 [PDF]
The World Health Organisation (WHO) has set ambitious goals to reduce the global disease burden associated with, and eventually eliminate, viral ...
A Hill +29 more
core +1 more source
Bee products as alternatives in the treatment of viral infections
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
ABSTRACT Hepatitis B and C viruses (HBV and HCV) remain among the leading causes of liver disease worldwide. Current antiviral drugs, such as nucleotide analogues (NAs), can reduce the replication of new HBV and HCV infections but cannot completely eliminate chronic infections.
Meng‐Fan Li +3 more
wiley +1 more source

