Results 81 to 90 of about 5,314 (201)

Effects of Sofosbuvir/Velpatasvir Therapy on Extrahepatic Manifestations in Patients With Type 2 Diabetes and Chronic Hepatitis C: Insights From a Nationwide Hepatitis C Virus Registry in Taiwan

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 41, Issue 11, November 2025.
ABSTRACT This study examines the impact of hepatitis C virus (HCV) eradication through sofosbuvir/velpatasvir (SOF/VEL) treatment on glycated hemoglobin (HbA1c) levels in patients with chronic hepatitis C and type 2 diabetes mellitus (T2DM). Utilizing data from the Taiwan HCV Registry, a retrospective analysis was conducted on 2180 patients who met the
Szu‐Jen Wang   +43 more
wiley   +1 more source

Survival of patients with HCV cirrhosis and sustained virologic response is similar to the general population. [PDF]

open access: yes, 2016
Background & Aims: Life expectancy of patients with compensated hepatitis C virus (HCV) cirrhosis achieving sustained virologic response (SVR) is limited by liver events as compared to the general population. Thus, survival benefit of SVR remains to
Aghemo A   +12 more
core   +1 more source

High Efficiency and Safety of Hepatitis C Treatment Among People Who Inject Drugs in Vietnam

open access: yesJournal of Viral Hepatitis, Volume 32, Issue 11, November 2025.
ABSTRACT People who inject drugs (PWID) are highly affected by hepatitis C (HCV) worldwide, particularly in low‐ and middle‐income countries (LMICs), where access to addiction services is often limited. Reducing the burden of HCV, as promoted by WHO, requires effective interventions in this high‐risk population.
Didier Laureillard   +21 more
wiley   +1 more source

Performance Evaluation of the Elecsys HCV Duo Immunoassay in the Public Healthcare Setting in Cape Town, South Africa

open access: yesJournal of Viral Hepatitis, Volume 32, Issue 11, November 2025.
ABSTRACT Improved HCV diagnosis and linkage to care is crucial to achieve WHO 2030 elimination targets. Simplification of diagnostics remains key. We evaluated the performance of Elecsys HCV Duo antigen/antibody immunoassay in patients using public healthcare in Cape Town, South Africa. 253 HCV seropositive and 214 seronegative samples were tested, and
Diana R. Hardie   +6 more
wiley   +1 more source

Developing a community HCV service: project ITTREAT (Integrated Community based Test - stage - TREAT) service for people who inject drugs [PDF]

open access: yes, 2017
Liver disease is now the third most common cause of premature death in the UK, with chronic viral hepatitis being an important contributory factor.
Hashim, Ahmed   +3 more
core   +1 more source

Multicomponent Synthesis of Fluorine‐Containing Bioactive Compounds and Drugs

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 38, October 15, 2025.
Multicomponent reactions are robust synthetic tools to assamble complex polyheterocycles and other interesting molecular architectures with potential application in medicinal chemistry, including their fluorine‐containing analogues. Fluorine atoms placed strategically into bioactive molecules often enhance essential pharmacokinetic parameters like ...
Ivette Morales‐Salazar   +7 more
wiley   +1 more source

Cost-utility analysis of interferon-free treatments for patients with early-stage genotype 1 hepatitis C virus in Brazil

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION We conducted a cost-utility analysis of available interferon-free treatments for patients with early-stage genotype 1 chronic hepatitis C based on a Brazilian public health system perspective.
Vinicius Lins Ferreira   +3 more
doaj   +1 more source

Hepatocellular carcinoma [PDF]

open access: yes, 2018
Liver cancer is the second leading cause of cancer-related deaths globally and has an incidence of approximately 850,000 new cases per year. Hepatocellular carcinoma (HCC) represents approximately 90% of all cases of primary liver cancer.
Gores, Gregory   +6 more
core   +1 more source

Противовирусные лекарственные средства для лечения гепатита C [PDF]

open access: yes, 2019
ГЕПАТИТ C /ЛЕК ТЕРПАРЕНТЕРАЛЬНО-ПЕРЕДАВАЕМЫЙ ГЕПАТИТ НИ-A, НИ-B /ЛЕК ТЕРПРОТИВОВИРУСНЫЕ СРЕДСТВА /ХИМЛЕКАРСТВ ХИМИЧЕСКАЯ СТАБИЛЬНОСТЬИНГИБИТОРЫ ПРОТЕАЗЫ NS3/NS4АИНГИБИТОРЫ БЕЛКА NS5AИНГИБИТОРЫ NS5B ПОЛИМЕРАЗЫДан обзор химической структуры и её связи с ...
Жерносек, А. К.   +1 more
core  

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