Results 1 to 10 of about 5,192 (61)
In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): A variety of signaling molecules have been identified that play a role in angiogenesis, of prime importance, vascular endothelial growth factor (VEGF) and its resceptor (VEGFR), which is highly expressed in most human solid tumors ...
Mohammad Hosseininejad-Chafi +9 more
doaj +1 more source
In vitro combination therapy of pathologic angiogenesis using anti-vascular endothelial growth factor and anti-neuropilin-1 nanobodies [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Emergence of resistant tumor cells to the current therapeutics is the main hindrance in cancer treatment. Combination therapy, which mixes two or more drugs, is a way to overcome resistant problems of cancer cells to current treatments ...
Nastaran Mohseni +4 more
doaj +1 more source
Toxins, 2021 Bungarus multicinctus, the Chinese krait, is a highly venomous elapid snake which causes considerable morbidity and mortality in southern China. B.
Qing Liang +4 more
doaj +1 more source
Toxins, 2022 Despite antivenoms being the only established specific treatment for neuromuscular paralysis arising from snake envenoming, their ability to reverse the post-synaptic neurotoxicity in snake envenoming is poorly understood.
Tam M. Huynh +3 more
doaj +1 more source
Toxins, 2023 The venom of the Russell’s viper (Daboia siamensis) contains neurotoxic and myotoxic phospholipase A2 toxins which can cause irreversible damage to motor nerve terminals.
Mimi Lay +3 more
doaj +1 more source
Toxins, 2022 Daboia siamensis (Russell’s viper) is a highly venomous and medically important snake in China, as well as much of Asia. There is minimal information on the pharmacological activity of the venom of the Chinese species, and currently no commercially ...
Mimi Lay +3 more
doaj +1 more source
Biomedicines, 2020 The Chinese Cobra (Naja atra) is an elapid snake of major medical importance in southern China. We describe the in vitro neurotoxic, myotoxic, and cytotoxic effects of N.
Qing Liang +4 more
doaj +1 more source
Expression and Purification of Functional Human Vascular Endothelial Growth Factor-A121; the Most Important Angiogenesis Factor [PDF]
Advanced Pharmaceutical Bulletin, 2014 Purpose: Angiogenesis or formation of new blood vessels is an essential process for tumor growth, invasion and metastasis. Vascular Endothelial Growth Factor (VEGF) and its receptors play an important role in angiogenesis-dependent tumors.
Fatemeh Kazemi-Lomedasht +7 more
doaj +1 more source
Toxins, 2022 Snake venom is an adaptive ecological trait that has evolved primarily as a form of prey subjugation. Thus, the selection pressure for toxin diversification is exerted by the prey’s physiological targets, with this pressure being particularly acute for ...
Uthpala Chandrasekara +2 more
doaj +1 more source
On the occurrence of Persian Gulf Sea Snake, Hydrophis lapemoides (Gray, 1849) (Reptilia, Squamata, Elapidae, Hydrophiinae), along the coast of Bangladesh [PDF]
Check List, 2021 We provide the first evidence of the presence of the Persian Gulf Sea Snake, Hydrophis lapemoides (Gray, 1849), along the coast of Bangladesh. This species was assumed to exist in there, but neither specimens nor confirmed observations exist until now ...
Mohammad Abdul Wahed Chowdhury +5 more
doaj +3 more sources