Results 1 to 10 of about 153,842 (313)
In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): A variety of signaling molecules have been identified that play a role in angiogenesis, of prime importance, vascular endothelial growth factor (VEGF) and its resceptor (VEGFR), which is highly expressed in most human solid tumors ...
Mohammad Hosseininejad-Chafi +9 more
doaj +1 more source
In vitro combination therapy of pathologic angiogenesis using anti-vascular endothelial growth factor and anti-neuropilin-1 nanobodies [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Emergence of resistant tumor cells to the current therapeutics is the main hindrance in cancer treatment. Combination therapy, which mixes two or more drugs, is a way to overcome resistant problems of cancer cells to current treatments ...
Nastaran Mohseni +4 more
doaj +1 more source
Toxins, 2022 Despite antivenoms being the only established specific treatment for neuromuscular paralysis arising from snake envenoming, their ability to reverse the post-synaptic neurotoxicity in snake envenoming is poorly understood.
Tam M. Huynh +3 more
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Venoms, venomics, antivenomics [PDF]
FEBS Letters, 2009 Venoms comprise mixtures of peptides and proteins tailored by Natural Selection to act on vital systems of the prey or victim. Here we review our proteomic protocols for uncoiling the composition, immunological profile, and evolution of snake venoms. Our long‐term goal is to gain a deep insight of all viperid venom proteomes.
Calvete Chornet, Juan José +4 more
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Toxins, 2021 Bungarus multicinctus, the Chinese krait, is a highly venomous elapid snake which causes considerable morbidity and mortality in southern China. B.
Qing Liang +4 more
doaj +1 more source
Expression and Purification of Functional Human Vascular Endothelial Growth Factor-A121; the Most Important Angiogenesis Factor [PDF]
Advanced Pharmaceutical Bulletin, 2014 Purpose: Angiogenesis or formation of new blood vessels is an essential process for tumor growth, invasion and metastasis. Vascular Endothelial Growth Factor (VEGF) and its receptors play an important role in angiogenesis-dependent tumors.
Fatemeh Kazemi-Lomedasht +7 more
doaj +1 more source
Hymenoptera Allergens: From Venom to “Venome” [PDF]
Frontiers in Immunology, 2014 In Western Europe, Hymenoptera venom allergy (HVA) primarily relates to venoms of the honeybee and the common yellow jacket. In contrast to other allergen sources, only a few major components of Hymenoptera venoms had been characterized until recently.
Spillner, Edzard +2 more
openaire +5 more sources
Bee Venom: From Venom to Drug [PDF]
Molecules, 2021 Insects of the order Hymenoptera have a defensive substance that contains many biologically active compounds. Specifically, venom from honeybees (Apis mellifera) contains many enzymes and peptides that are effective against various diseases. Different research papers stated the possibility of using bee venom (a direct bee sting or in an injectable form)
Abdelwahab Khalil +3 more
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Biomedicines, 2020 The Chinese Cobra (Naja atra) is an elapid snake of major medical importance in southern China. We describe the in vitro neurotoxic, myotoxic, and cytotoxic effects of N.
Qing Liang +4 more
doaj +1 more source
Toxins, 2022 Daboia siamensis (Russell’s viper) is a highly venomous and medically important snake in China, as well as much of Asia. There is minimal information on the pharmacological activity of the venom of the Chinese species, and currently no commercially ...
Mimi Lay +3 more
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