Results 211 to 220 of about 159,674 (308)

Venom-Derived Peptides in Breast Cancer: Pharmacological Mechanisms and Medicinal Chemistry-Guided Translational Development. [PDF]

Arch Pharm (Weinheim)
Amen RA, Farid A, Abdel-Rahman MA, El-Sherif AA, Hassan YM, Shehata NR, Ahmed RH, El-Sayed WM.   +7 more
europepmc   +1 more source

Dioxygen Reduction at a Cu(I) Complex Supported by a Macrocyclic N3O Ligand System

Chemistry – A European Journal, EarlyView.
A non‐reactive [CuI(14‐TMC)]+ complex is transformed to an efficient catalyst [CuI(14‐TMCO)]+ (TMCO = 4,8,12‐trimethyl‐1‐oxa‐4,8,12‐triazacyclotetradecane) for 4e−/4H+ reduction of O2 by N → O substitution. ABSTRACT CuI(14 TMCO) (1), involving a N3O‐macrocycle, reacts with O2 at cryogenic temperatures to yield an end‐on peroxodicopper(II) species.
Maximilian Schütze, Dibya Jyoti Barman, Christian Lorent, Kallol Ray   +3 more
wiley   +1 more source

Nature's antivenom: Combinations of conserved rattlesnake serum metalloproteinase inhibitors block the lethal action of viper venoms. [PDF]

Proc Natl Acad Sci U S A
Carroll SB, Ukken FP, Ayinuola YA, Escalona L, Suntravat M, Sanchez EE.   +5 more
europepmc   +1 more source

GH172 Difructose Dianhydride I Synthase: A Two‐Stepped Journey via Glycosylation and Cyclization Using QM/MM Metadynamics

Chemistry – A European Journal, EarlyView.
Unlocking the chemistry of caramel by simulations and experimental validation. αFFase1${\alpha }\rm{FFase1}$ converts inulobiose into difructose dianhydride I, one component of caramel, through two steps: a rate‐limiting glycosylation (with a rare sugar ring flip) followed by a cyclization step, guided by residues E85, K147, and N226.
Santiago Alonso‐Gil, Bruno Di Geronimo, Toma Kashima, Akihiro Ishiwata, Katsunori Tanaka, Kiyotaka Fujita, Shinya Fushinobu, Pedro A. Sánchez‐Murcia   +7 more
wiley   +1 more source

Naja atra SVPLA₂ contributes to venom-induced AKI via HRAS palmitoylation-dependent PI3K-AKT inactivation. [PDF]

J Lipid Res
Liu J, Chen S, Wu J, Tang S, Wen Z, Bi X, Yang Y, Huang C.   +7 more
europepmc   +1 more source

Vibrational Circular Dichroism Spectra of 2,5‐Diaminoterephtalate Macrocycles Reveal Distant Vibrational Exciton Coupling

Chemistry – A European Journal, EarlyView.
The energy level diagrams for the ν(C═O) and the δ(N─H) vibrations, resulting of combining in‐phase and out‐of‐phase modes on the basis of their local symmetries, was built by applying the exciton coupling theory to a new class of chiral macrocycles, based on the 2,5‐diaminoterephthalate scaffold.
Samara Medina, Krzysztof Nowak, Marek Grzybowski, Juan Casado, Francisco J. Ramírez   +4 more
wiley   +1 more source

Repurposed small molecule toxin inhibitors neutralise a diversity of venoms from the Neotropical viperid snake genus <i>Bothrops</i>. [PDF]

Elife
Clare RH, Westhorpe A, Stars E, Kazandjian TD, Albulescu LO, Menzies SK, Casewell NR.   +6 more
europepmc   +1 more source

Carboxylate–Probase Catalyzed Favorskii Reaction

Chemistry – A European Journal, EarlyView.
Stronger together: A combination of a carboxylate catalyst and a silylating agent generates a stronger base catalyst for a metal‐free catalytic addition of alkynes to aldehydes and ketones under chemoselective, O‐silylative conditions. The reaction is proposed to proceed via quaternary ammonium (Q+) cation – acetylide anion ion pairs, with chiral ...
Anton Bannykh, Sanna M. Stenfors, Anton Nechaev, John M. Fiskari, Petri M. Pihko   +4 more
wiley   +1 more source

Identification and Comparative Evaluation of Analgesic Components in Toad Venom on Inflammatory Pain. [PDF]

J Inflamm Res
Wen Y, Li R, Cui X, Zhang F, Zhang J.
europepmc   +1 more source

Hidden in Plain Sight: Aromaticity of Hexagonal Boron Nitride

Chemistry – A European Journal, EarlyView.
How apt is the nickname “white graphene” for hexagonal boron nitride (hBN)? Although graphene's aromaticity is well established, it is not known if hBN is aromatic. In this work, hBN's aromaticity is probed using magnetic and energetic criteria. Group‐theoretic considerations and magnetically induced current density maps are used to further reveal the ...
Suryakanti Debata, Sai Krishna Narayanan, Pratibha Dev   +2 more
wiley   +1 more source