Results 21 to 30 of about 38,232 (251)

Isolation and Pharmacological Characterization of α-Elapitoxin-Ot1a, a Short-Chain Postsynaptic Neurotoxin from the Venom of the Western Desert Taipan, Oxyuranus temporalis

open access: yesToxins, 2016
Taipans (Oxyuranus spp.) are elapids with highly potent venoms containing presynaptic (β) and postsynaptic (α) neurotoxins. O. temporalis (Western Desert taipan), a newly discovered member of this genus, has been shown to possess venom which displays ...
Carmel M. Barber   +2 more
doaj   +1 more source

In vivo immunotherapy of lung cancer using cross-species reactive vascular endothelial growth factor nanobodies [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
Objective(s): Lung cancer is the main leading cause of cancer death worldwide. Angiogenesis is the main step in proliferation and spreading of tumor cells.
vFatemeh Kazemi-Lomedasht v   +6 more
doaj   +1 more source

Isolation and Pharmacological Characterization of α-Elapitoxin-Oh3a, a Long-Chain Post-Synaptic Neurotoxin From King Cobra (Ophiophagus hannah) Venom

open access: yesFrontiers in Pharmacology, 2022
The King Cobra (Ophiophagus hannah) is the world’s largest venomous snake and has a widespread geographical distribution throughout Southeast Asia. Despite proteomic studies indicating the presence of postsynaptic neurotoxins in O.
Tam M. Huynh   +5 more
doaj   +1 more source

Comparative Studies of the Venom of a New Taipan Species, Oxyuranus temporalis, with Other Members of Its Genus

open access: yesToxins, 2014
Taipans are highly venomous Australo-Papuan elapids. A new species of taipan, the Western Desert Taipan (Oxyuranus temporalis), has been discovered with two specimens housed in captivity at the Adelaide Zoo.
Carmel M. Barber   +8 more
doaj   +1 more source

Isolation and Characterization of Two Postsynaptic Neurotoxins From Indian Cobra (Naja Naja) Venom

open access: yesFrontiers in Pharmacology, 2022
The Indian Cobra (Naja naja) is among the “Big Four” responsible for most of the snakebite envenoming cases in India. Although recent proteomic studies suggest the presence of postsynaptic neurotoxins in N.
Tam M. Huynh   +5 more
doaj   +1 more source

Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2022
Objective(s): One of the important interactions in controlling the human immune system is the reaction between checkpoint proteins such as programmed cell death-1 (PD-1) and its ligand, PD-L1.
Akbar Oghalaei   +9 more
doaj   +1 more source

The electronic structure and dipole moment of charybdotoxin, a scorpion venom peptide with K+ channel blocking activity [PDF]

open access: yesComputational and Theoretical Chemistry 963 (2011) 384-393, 2010
The electronic structure of charybdotoxin (ChTX), a scorpion venom peptide that is known to act as a potassium channel blocker, is investigated with the aid of quantum mechanical calculations. The dipole moment vector (145 D) of ChTX can be stirred by the full length KcsA potassium channel's macrodipole (403 D) thereby assuming the proper orientation ...
arxiv   +1 more source

Toxins and venoms [PDF]

open access: yesCurrent Biology, 2009
The compounds that we recognize as toxins and venoms span an enormous diversity of pharmacological and ecological functions. The selection pressures driving the modification of venoms and toxins are fundamentally different from those of other proteins, and result in somewhat different evolutionary dynamics.
openaire   +3 more sources

Home - About - Disclaimer - Privacy