Results 21 to 30 of about 153,842 (313)

Isolation and Pharmacological Characterization of α-Elapitoxin-Ot1a, a Short-Chain Postsynaptic Neurotoxin from the Venom of the Western Desert Taipan, Oxyuranus temporalis

Toxins, 2016
Taipans (Oxyuranus spp.) are elapids with highly potent venoms containing presynaptic (β) and postsynaptic (α) neurotoxins. O. temporalis (Western Desert taipan), a newly discovered member of this genus, has been shown to possess venom which displays ...
Carmel M. Barber, Muhamad Rusdi Ahmad Rusmili, Wayne C. Hodgson   +2 more
doaj   +1 more source

Isolation and Pharmacological Characterization of α-Elapitoxin-Oh3a, a Long-Chain Post-Synaptic Neurotoxin From King Cobra (Ophiophagus hannah) Venom

Frontiers in Pharmacology, 2022
The King Cobra (Ophiophagus hannah) is the world’s largest venomous snake and has a widespread geographical distribution throughout Southeast Asia. Despite proteomic studies indicating the presence of postsynaptic neurotoxins in O.
Tam M. Huynh, Anjana Silva, Anjana Silva, Geoffrey K. Isbister, Geoffrey K. Isbister, Wayne C. Hodgson   +5 more
doaj   +1 more source

Identification of key genes and microRNAs involved in the Androctonus Crassicauda apoptosis pathway [PDF]

مجله بیوتکنولوژی کشاورزی, 2021
Objective The occurrence of planned cell death or apoptosis as a protected method is controlled by a number of genes that used to remove unnecessary cells. This cellular event is involved in immune and disease-related systems.
Fatemeh Salabi, Hadeih Jafari, Alireza Forouzan, Mohammad Nemati   +3 more
doaj   +1 more source

Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)

Toxins, 2018
Snakebite is a global tropical disease that has long had huge implications for human health and well-being. Despite its long-standing medical importance, it has been the most neglected of tropical diseases.
Mátyás A. Bittenbinder, Christina N. Zdenek, Bianca op den Brouw, Nicholas J. Youngman, James S. Dobson, Arno Naude, Freek J. Vonk, Bryan G. Fry   +7 more
doaj   +1 more source

Isolation and Characterization of Two Postsynaptic Neurotoxins From Indian Cobra (Naja Naja) Venom

Frontiers in Pharmacology, 2022
The Indian Cobra (Naja naja) is among the “Big Four” responsible for most of the snakebite envenoming cases in India. Although recent proteomic studies suggest the presence of postsynaptic neurotoxins in N.
Tam M. Huynh, Anjana Silva, Anjana Silva, Geoffrey K. Isbister, Geoffrey K. Isbister, Wayne C. Hodgson   +5 more
doaj   +1 more source

Cross-Neutralisation of In Vitro Neurotoxicity of Asian and Australian Snake Neurotoxins and Venoms by Different Antivenoms

Toxins, 2016
There is limited information on the cross-neutralisation of neurotoxic venoms with antivenoms. Cross-neutralisation of the in vitro neurotoxicity of four Asian and four Australian snake venoms, four post-synaptic neurotoxins (α-bungarotoxin, α-elapitoxin-
Anjana Silva, Wayne C. Hodgson, Geoffrey K. Isbister   +2 more
doaj   +1 more source

Webslinger vs. Dark Knight: First record of a false widow spider Steatoda nobilis preying on a pipistrelle bat in Britain

Ecosphere, 2022
The noble false widow spider Steatoda nobilis continues to expand its range globally with possible implications for public health and native species. Of the European Union list of 66 species of invasive plants and animals, none are spiders. S. nobilis is
John P. Dunbar, Aiste Vitkauskaite, Colin Lawton, Ben Waddams, Michel M. Dugon   +4 more
doaj   +1 more source

First record of the Condanarous sand snake (Psammophis condanarus)(Reptilia: Squamata: Lamprophiidae) from Bangladesh

Journal of Asia-Pacific Biodiversity, 2020
The occupancy of the Condanarous sand snake Psammophis condanarus in peninsular India and its distribution in West Bengal, adjacent to Bangladesh, indicate its possible existence in the country but confirmation was wanting till date.
Ibrahim K.A. Haidar, Borhan B. Romon, Mohammad A.W. Chowdhury   +2 more
doaj   +1 more source

Venom Down Under: Dynamic Evolution of Australian Elapid Snake Toxins

Toxins, 2013
Despite the unparalleled diversity of venomous snakes in Australia, research has concentrated on a handful of medically significant species and even of these very few toxins have been fully sequenced.
Timothy N. W. Jackson, Kartik Sunagar, Eivind A. B. Undheim, Ivan Koludarov, Angelo H. C. Chan, Kate Sanders, Syed A. Ali, Iwan Hendrikx, Nathan Dunstan, Bryan G. Fry   +9 more
doaj   +1 more source

An in vivo examination of the differences between rapid cardiovascular collapse and prolonged hypotension induced by snake venom

Scientific Reports, 2019
We investigated the cardiovascular effects of venoms from seven medically important species of snakes: Australian Eastern Brown snake (Pseudonaja textilis), Sri Lankan Russell’s viper (Daboia russelii), Javanese Russell’s viper (D.
Rahini Kakumanu, Barbara K. Kemp-Harper, Anjana Silva, Sanjaya Kuruppu, Geoffrey K. Isbister, Wayne C. Hodgson   +5 more
doaj   +1 more source