Results 21 to 30 of about 23,074 (307)

Discovering Venom-Derived Drug Candidates Using Differential Gene Expression

open access: yesToxins, 2023
Venoms are a diverse and complex group of natural toxins that have been adapted to treat many types of human disease, but rigorous computational approaches for discovering new therapeutic activities are scarce.
Joseph D. Romano   +6 more
doaj   +1 more source

Quo Vadis Venomics? A Roadmap to Neglected Venomous Invertebrates

open access: yesToxins, 2014
Venomics research is being revolutionized by the increased use of sensitive -omics techniques to identify venom toxins and their transcripts in both well studied and neglected venomous taxa.
Bjoern Marcus von Reumont   +2 more
doaj   +1 more source

Characterization of a Lab-Scale Process to Produce Whole IgG Antivenom Covering Scorpion Stings by Genus Tityus and Centruroides of Colombia

open access: yesPharmaceuticals, 2022
Scorpion stings are a public health event in Colombia lacking official epidemiological data, and are considered a medical emergency. Despite the two local producers of antivenoms, neither of them is currently manufacturing scorpion antivenoms. We present
Sebastian Estrada-Gomez   +4 more
doaj   +1 more source

Saliva: indicazioni terapeutiche, modalità di impiego e lessico nella Naturalis Historia di Plinio tra fonti e ricezione

open access: yesPallas, 2020
In this report the testimonies of Pliny concerning the term saliva (28, 35, 1-39, 8) are examined. Moreover at this «monographic» moment, which presents about 19 cases of therapeutic or magical application of human saliva, the other passages in the ...
Livia Radici, Paola Radici Colace
doaj   +1 more source

Mass spectrometry‐based top‐down and bottom‐up approaches for proteomic analysis of the Moroccan Buthus occitanus scorpion venom

open access: yesFEBS Open Bio, 2021
Buthus occitanus (B. occitanus) is one of the most dangerous scorpions in the world. Despite the involvement of B. occitanus scorpion in severe cases of envenomation in Morocco, no study has focused yet on the proteomic composition of the Moroccan B ...
Khadija Daoudi   +8 more
doaj   +1 more source

Bioactive peptides from venoms against glioma progression

open access: yesFrontiers in Oncology, 2022
Venoms are complex mixtures of different molecules and ions. Among them, bioactive peptides have been found to affect cancer hallmarks, such as cell proliferation, cell invasion, cell migration, and can also modulate the immune response of normal and ...
Bernarda Majc   +6 more
doaj   +1 more source

Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19

open access: yesToxins, 2023
Animal-derived venoms are complex mixtures of toxins triggering important biological effects during envenomings. Although venom-derived toxins are known for their potential of causing harm to victims, toxins can also act as pharmacological agents. During
Isadora Oliveira   +8 more
doaj   +1 more source

Bothrops atrox and Bothrops lanceolatus Venoms In Vitro Investigation: Composition, Procoagulant Effects, Co-Factor Dependency, and Correction Using Antivenoms

open access: yes, 2023
Bothrops venoms are rich in enzymes acting on platelets and coagulation. This action is dependent on two major co-factors, i.e., calcium and phospholipids, while antivenoms variably neutralize venom-related coagulopathy effects.
Rabah Gahoual   +10 more
core   +1 more source

Field study on scorpions and scorpionism in the southeast of El Jadida, Morocco [PDF]

open access: yesBIO Web of Conferences
Morocco has a rich and diverse fauna of scorpions. However, certain regions such as Boulaouane remain underdocumented despite their importance for public health.
Ammouch Khawla   +5 more
doaj   +1 more source

Differences between Two Groups of Burmese Vipers (Viperidae: Azemiops) in the Proteomic Profiles, Immunoreactivity and Biochemical Functions of Their Venoms

open access: yes, 2022
Two recently revised Azemiops snakes with apparent differences in their external appearances and skeletal morphologies but unclear genetic boundaries have been proposed. Some researchers have refrained from using the newly proposed taxonomy because these
Gao, Jian-Fang   +11 more
core   +1 more source

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