Results 51 to 60 of about 11,226 (259)

One-Step Chromatographic Approach for Purifying Peptides and Proteins from Venoms

Separations
Animal venoms are intricate and teem with potential for groundbreaking medical advancements. Although traditional methods for purifying venom proteins are effective, they usually require complicated, multi-step processes that lead to lower yields.
Yasmine Boughanmi, Soioulata Aboudou, Kayané Boyadjian, Acil Charouandi, Sarra Bouzid, Thelma Barnetche, Pascal Mansuelle, Régine Lebrun, Didier Gigmes, Harold de Pomyers, Kamel Mabrouk   +10 more
doaj   +1 more source

A new scenario of bioprospecting of Hymenoptera venoms through proteomic approach

Journal of Venomous Animals and Toxins including Tropical Diseases, 2011
Venoms represent a huge and essentially unexplored reservoir of bioactive components that may cure diseases that do not respond to currently available therapies.
LD Santos, M Pieroni, ARS Menegasso, JRAS Pinto, MS Palma   +4 more
doaj   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

Arthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok, Samantha Morais, William K. Silverstein, Clare L. Atzema, Gregory Choy, Priyanka Chandratre, Ping Li, Jessica Widdifield   +7 more
wiley   +1 more source

A Lightweight Procedural Layer for Hybrid Experimental–Computational Workflows in Materials Science

Advanced Engineering Materials, EarlyView.
We unveil a prototype hybrid‐workflow framework that fuses automatedcomputation with hands‐on experiments. Built atop pyiron, a lightweight, parameterized layer translates procedure descriptions into executable manual steps, syncing instrument settings, human interventions, and data capture in real‐time today.
Steffen Brinckmann, Sarath Menon, Raphael Röske, Johannes Steinhülb, Michael Selzer, Jan Janssen, Tilmann Hickel, Ruth Schwaiger, Jörg Neugebauer   +8 more
wiley   +1 more source

The Nonpeptide Low Molecular Mass Toxins from Spider Venoms

, 2016
Spiders occupy most of the ecological niches of the planet, revealing a huge adaptive plasticity, reflected in the chemical diversity of their venom toxins.
DiegoGarcia, E., Gopalakrishnakone, P., Gomes, Paulo Cesar [UNESP], Corzo, G., Palma, Mario Sergio [UNESP], DeLima, M. E.   +5 more
core   +1 more source

Distinct Microstructural Characteristic Lengths Defining Notch Fatigue Crack Initiation and Propagation, and Defect Tolerance in Advanced Steels

Advanced Engineering Materials, EarlyView.
Schematic representation of modes of microcrack nucleation, growth and temporary arrestment at different boundaries, with the criteria for crack propagation in three scenarios: (1) large notch, (2) defect/small sharp notch, and (3) long crack. This work revisits and integrates results on the fatigue behavior of advanced bainitic steels (in particular ...
Lucia Morales‐Rivas
wiley   +1 more source

Genotoxic Activity of Cerastes cerastes Viper Venom Using Alkaline Single-Cell Gel Electrophoresis

Biology
In Morocco, Cerastes cerastes snake is responsible for numerous cases of human envenomation, leading to both local and systemic pathophysiological disturbances.
Zineb Ouhemmou, Nouhaila Benbaak, Zahraa Laouija, Soukaina Behlaouane, Nouhaila El Fenni, Mouad Mkamel, Mounia Cherki, Mehdi Karkouri, Fatima Chgoury   +8 more
doaj   +1 more source

Evaluation of the Lethal Potency of Scorpion and Snake Venoms and Comparison between Intraperitoneal and Intravenous Injection Routes

Toxins, 2014
Scorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such stings and bites of venomous animals occur every year worldwide.
Naoual Oukkache, Rachid Eljaoudi, Noreddine Ghalim, Fatima Chgoury, Balkiss Bouhaouala, Naima Elmdaghri, Jean-Marc Sabatier   +6 more
doaj   +1 more source

Venomous Snakebites

Medicina, 2011
More than 5 million people are bitten by venomous snakes annually and more than 100 000 of them die. In Europe, one person dies due to envenomation every 3 years. There is only one venomous snake species in Lithuania – the common adder (Vipera berus) – which belongs to the Viperidae family; however, there are some exotic poisonous snakes in the zoos ...
Adukauskienė, Dalia, Varanauskienė, Eglė, Adukauskaitė, Agnė   +2 more
openaire   +2 more sources

Potency Testing of Venoms and Antivenoms in Embryonated Eggs: An Ethical Alternative to Animal Testing

, 2021
Venoms are complex mixtures of biologically active molecules that impact multiple physiological systems. Manufacture of antivenoms (AVs) therefore requires potency testing using in vivo models to ensure AV efficacy. As part of ongoing research to replace
Erin E. Verity, Kathy Stewart, Chi Ong, Steven Rockman, Kirsten Vandenberg   +4 more
core   +1 more source