Results 51 to 60 of about 5,048,560 (285)

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Prednisolone as preservation additive prevents from ischemia reperfusion injury in a rat model of orthotopic lung transplantation [PDF]

, 2013
The lung is, more than other solid organs, susceptible for ischemia reperfusion injury after orthotopic transplantation. Corticosteroids are known to potently suppress pro-inflammatory processes when given in the post-operative setting or during ...
Haitham Mutlak, Paulus, Patrick, Mutlak, Haitham, Johannes Holfeld, Haitham Mutlak (452006), Sabine Tacke (318720), David Stay (452009), Patrick Paulus, Holfeld, Johannes, Urbschat, Anja, Christin Reissig, Pia Alexandra Ockelmann, Reissig, Christin, Zacharowski, Kai, Tacke, Sabine, Bertram Scheller (318724), Stay, David, Bertram Scheller, Ockelmann, Pia Alexandra, Scheller, Bertram, Kai Zacharowski (77285), Sabine Tacke, Johannes Holfeld (318725), Patrick Paulus (318716), Anja Urbschat, Kai Zacharowski, Christin Reissig (452008), Anja Urbschat (318726), David Stay, Pia Alexandra Ockelmann (452007)   +29 more
core   +2 more sources

Purinergic signalling links mechanical breath profile and alveolar mechanics with the pro-inflammatory innate immune response causing ventilation-induced lung injury

Purinergic Signalling Purinergic Signalling, 2017
Severe pulmonary infection or vigorous cyclic deformation of the alveolar epithelial type I (AT I) cells by mechanical ventilation leads to massive extracellular ATP release.
D. Hasan, P. Blankman, G. Nieman
semanticscholar   +1 more source

Leukocyte sequestration in pulmonary microvessels and lung injury following systemic complement activation in rabbits [PDF]

, 1999
Inflammatory reactions are associated with sequestration of leukocytes in the lung. Complement activation leads to accumulation of leukocytes in alveolar septa and alveoli, to lung edema and hemorrhage.
Kuhnle, Gerhard E. H., Kuebler, Wolfgang M., Kiefmann, Rainer, Groh, Joachim, Goetz, Alwin Eduard, Sckell, Axel   +5 more
core   +1 more source

Mechanical power in AVM-2 versus conventional ventilation modes in various ARDS lung models. Bench study

, 2022
Introduction Mechanical power has been linked to ventilator induced lung injury and mortality in acute respiratory distress syndrome (ARDS). Adaptive Ventilator Mode-2 (AVM-2) is a closed-loop pressure-controlled mode with an optimal targeting scheme ...
Yeo, Jihun, Maan Gozun, Jihun Yeo, Claudio Luciano Franck, Shah, Parthav, Daoud, Ehab, Franck, Claudio, Keitoku, Koichi, Parthav Shah, Ehab G. Daoud, Keitoku Koichi   +10 more
core   +1 more source

Low-molecular-weight heparin reduces hyperoxia-augmented ventilator-induced lung injury via serine/threonine kinase-protein kinase B

Respiratory Research, 2011
Background High-tidal-volume mechanical ventilation and hyperoxia used in patients with acute lung injury (ALI) can induce the release of cytokines, including high-mobility group box-1 (HMGB1), oxygen radicals, neutrophil infiltration, and the disruption
Huang Chung-Chi, Yang Cheng-Ta, Li Li-Fu, Liu Yung-Yang, Kao Kuo-Chin, Lin Horng-Chyuan   +5 more
doaj   +1 more source

Personalizing mechanical ventilation according to physiologic parameters to stabilize alveoli and minimize ventilator induced lung injury (VILI)

Intensive Care Medicine Experimental, 2017
It has been shown that mechanical ventilation in patients with, or at high-risk for, the development of acute respiratory distress syndrome (ARDS) can be a double-edged sword.
G. Nieman, J. Satalin, P. Andrews, H. Aiash, N. Habashi, L. Gatto   +5 more
semanticscholar   +1 more source

Platelet-activating factor receptor plays a role in lung injury and death caused by influenza A in mice [PDF]

, 2010
Influenza A virus causes annual epidemics which affect millions of people worldwide. A recent Influenza pandemic brought new awareness over the health impact of the disease.
Sousa, Lirlandia P., Garcia, Cristina C., Remo C Russo, Salgado, Ana Paula C., Geovanni D. Cassali, Mauro M. Teixeira, Tavares, L.P., Polidoro, Rafael B., Caio T Fagundes, Luciana P Tavares, Tavares, Luciana P., Machado, A.V., Salgado, Ana Paula Carneiro, Rodrigo Guabiraba, Garcia, C.C., Russo, R.C., Cristiana C Garcia, Guabiraba Brito, R., Remo C. Russo, Alexandre V Machado, Machado, Alexandre Vieira, Polidoro, Rafael Barbosa, Caio T. Fagundes, Cassali, Geovanni D., Teixeira, Mauro Martins, Cassali, Geovanni Dantas, Mauro M Teixeira, Lirlândia P. Sousa, Fagundes, C.T., Salgado, A.P.C., Ana Paula C. Salgado, Cassali, G.D., Garcia, Cristiana Couto, Russo, Remo de Castro, Russo, Remo C., Rafael B. Polidoro, Sousa, L.P., Teixeira, M.M., Ana Paula C Salgado, Alexandre V. Machado, Rafael B Polidoro, Machado, Alexandre V., Fagundes, Caio T., Guabiraba, Rodrigo, Cristiana C. Garcia, Polidoro, R.B., Lirlândia P Sousa, Sousa, Lirlândia Pires de, Geovanni D Cassali, Luciana P. Tavares, Teixeira, Mauro M., Salgado, Ana Paula C, Tavares, Luciana P, Machado, Alexandre V, Polidoro, Rafael B, Cassali, Geovanni D, Teixeira, Mauro M, Sousa, Lirlândia P, Garcia, Cristiana C, Russo, Remo C, Fagundes, Caio T   +60 more
core   +2 more sources

Early Light Sedation Increased the Duration of Mechanical Ventilation in Patients With Severe Lung Injury

, 2023
application/pdfIntroduction: The international guidelines recommend light sedation management for patients receiving mechanical ventilation. One of the benefits of light sedation management during mechanical ventilation is the preservation of spontaneous
SIMOJO, Nobutake, 大内, 玲, 鳩崎, 千絵, HATOZAKI, Chie, サクラモト, ヒデアキ, オオウチ, アキラ, シモジョウ, ノブタケ, INOUE, Yoshiaki, SAKURAMOTO, Hideaki, イノウエ, ヨシアキ, 下條, 信威, 櫻本, 秀明, ハトザキ, チエ, 井上, 貴昭, OUCHI, Akira   +14 more
core   +1 more source

Динаміка показників легеневого ушкодження за умови експериментального HCl-індукованого гострого ураження легень = Dynamics of pulmonary damage parameters in experimental HCl-induced acute lung injury [PDF]

, 2014
Hryshchuk L. A., Besky V. O., Marushchak M. I. Динаміка показників легеневого ушкодження за умови експериментального HCl-індукованого гострого ураження легень = Dynamics of pulmonary damage parameters in experimental HCl-induced acute lung injury ...
Besky, V. O., Hryshchuk, L. A., Marushchak, M. I.   +2 more
core   +1 more source