Results 41 to 50 of about 5,048,560 (285)

Suppressing NF-κB and NKRF Pathways by Induced Pluripotent Stem Cell Therapy in Mice with Ventilator-Induced Lung Injury. [PDF]

PLoS ONE, 2013
BACKGROUNDHigh-tidal-volume mechanical ventilation used in patients with acute lung injury (ALI) can induce the release of inflammatory cytokines, as macrophage inflammatory protein-2 (MIP-2), recruitment of neutrophils, and disruption of alveolar ...
Yung-Yang Liu, Li-Fu Li, Cheng-Ta Yang, Kai-Hsi Lu, Chung-Chi Huang, Kuo-Chin Kao, Shih-Hwa Chiou   +6 more
doaj   +1 more source

Monitoring of lung edema by microwave reflectometry during lung ischemia-reperfusion injury in vivo [PDF]

, 2006
It is still unclear whether lung edema can be monitored by microwave reflectometry and whether the measured changes in lung dry matter content (DMC) are accompanied by changes in PaO(2) and in pro-to anti-inflammatory cytokine expression (IFN-gamma and ...
Metzger, R. P., Gross, W., Nowak, K., Schaefer, M., Post, S., Gebhard, M. M., Hohenberger, P.   +6 more
core   +1 more source

Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia [PDF]

, 2009
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD.
Hogmalm, Anna
core   +1 more source

Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund and is distributed by the Creative Commons CC-BY 3.0 license, under which all are free to reuse or distribute the article under the condition that this original publication ...
Romer, L. M., Simpson, Andrew, L. Bjermer, P. Kippelen, A. J. Simpson, L. M. Romer, Bjermer, Leif, Romer, L M., Simpson, AJ, Tufvesson, E, Anderson, S. D., Simpson, A. J., S. D. Anderson, Bjermer, L, Tufvesson, Ellen, Kippelen, P, Tufvesson, E., Romer, LM, Bjermer, L., Anderson, SD, Kippelen, P., E. Tufvesson   +21 more
core   +1 more source

Favorable outcome with early initiation of VV-ECMO for unilateral lung disease in children

Respiratory Medicine Case Reports, 2019
Unilateral lung diseases such as unilateral pneumonia, trauma or pulmonary hemorrhage can cause profound hypoxemic respiratory failure necessitating mechanical ventilation. These disorders are characterized by marked asymmetry in lung mechanics, with the
Hammad A. Ganatra, Daniah Shamim, Angela Farnan, Girish Deshpande   +3 more
doaj   +1 more source

Understanding the mechanisms of ventilator-induced lung injury using animal models

Intensive Care Medicine Experimental, 2023
Mechanical ventilation is a life-saving therapy in several clinical situations, promoting gas exchange and providing rest to the respiratory muscles. However, mechanical ventilation may cause hemodynamic instability and pulmonary structural damage, which
P. Silva, M. Scharffenberg, P. R. M. Rocco   +2 more
semanticscholar   +1 more source

The Beta Agonist Lung Injury TrIal (BALTI) : prevention trial protocol [PDF]

, 2011
Background: Acute lung injury complicates approximately 25-30% of subjects undergoing oesophagectomy. Experimental studies suggest that treatment with beta agonists may prevent the development of acute lung injury by decreasing inflammatory cell ...
Matthew W Cooke, Thickett, David R, Cooke, MW, Lamb, S. E. (Sallie E.), Thickett David R, David R Thickett, Cooke, Matthew (Professor of clinical systems design), Lamb, Sarah E, Gao, F, Perkins, Gavin D., Gates, S, Daniel Park, Mistry Dipesh, Alderson, D, Fang Gao, Gao, Fang; id_orcid, Alderson, Derek, Cooke Matthew W, Gao Fang, Mistry, D, Dipesh Mistry, Alderson Derek, Perkins, GD, Gao, Fang, Mistry, Dipesh, Park, Daniel P., Park Daniel, Cooke, Matthew W, Thickett, David R; id_orcid, Thickett, DR, Gates, Simon, Lamb, Sarah, Sarah E Lamb, Park, Daniel, Gavin D Perkins, Park, D, Perkins, Gavin D, Simon Gates, Thickett, David R., Smith, F. Gao (Fang Gao), Gates Simon, Lamb Sarah E, Derek Alderson, Perkins Gavin D, Lamb, SE   +44 more
core   +3 more sources

Lung-Cardiovascular Interactions and Derangements in ARDS. [PDF]

Compr Physiol
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Sanchez PA, O'Brien C, Legrand M, Calfee CS, Matthay MA.   +4 more
europepmc   +2 more sources

Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner

Scientific Reports, 2016
Mechanical ventilation (MV) is a therapeutic intervention widely used in the clinic to assist patients that have difficulty breathing due to lung edema, trauma, or general anesthesia.
Sha-Sha Tao, Montserrat Rojo de la Vega, Hector Quijada, G. Wondrak, Ting Wang, Joe G. N. Garcia, Donna D. Zhang   +6 more
semanticscholar   +1 more source

Superimposed high-frequency jet ventilation combined with continuous positive airway pressure/assisted spontaneous breathing improves oxygenation in patients with H1N1-associated ARDS [PDF]

, 2012
Background: Numerous cases of swine-origin 2009 H1N1 influenza A virus (H1N1)-associated acute respiratory distress syndrome (ARDS) bridged by extracorporeal membrane oxygenation (ECMO) therapy have been reported; however, complication rates are high. We
Wolf, Timo, Koch, Alexander, Rosenberger, Peter, Peter Rosenberger, Tobias M Bingold, Bertram Scheller, Scheller, Bertram, Jens Meier, Thomas Iber, Alexander Koch, Timo Wolf, Zacharowski, Kai, Kai Zacharowski, Iber, Thomas, Bingold, Tobias Michael, Meier, Jens   +15 more
core   +1 more source