Results 91 to 100 of about 3,803,785 (155)

Identification of the co-differentially expressed hub genes involved in the endogenous protective mechanism against ventilator-induced diaphragm dysfunction. [PDF]

Skelet Muscle, 2022
Zhang D, Hao W, Niu Q, Xu D, Duan X.
europepmc   +1 more source

Prolonged mechanical ventilation alters the expression pattern of angio-neogenetic factors in a pre-clinical rat model.

PLoS ONE, 2013
ObjectiveMechanical ventilation (MV) is a life saving intervention for patients with respiratory failure. Even after 6 hours of MV, diaphragm atrophy and dysfunction (collectively referred to as ventilator-induced diaphragmatic dysfunction, VIDD) occurs ...
Christian S Bruells, Karen Maes, Rolf Rossaint, Debby Thomas, Nele Cielen, Christian Bleilevens, Ingmar Bergs, Ursina Loetscher, Agnes Dreier, Ghislaine Gayan-Ramirez, Brad J Behnke, Joachim Weis   +11 more
doaj   +1 more source

Rationale and design of a mechanistic clinical trial of JAK inhibition to prevent ventilator-induced diaphragm dysfunction. [PDF]

Respir Med, 2021
Shrager JB, Wang Y, Lee M, Nesbit S, Trope W, Konsker H, Fatodu E, Berry MS, Poulstides G, Norton J, Burdon T, Backhus L, Cooke R, Tang H.   +13 more
europepmc   +1 more source

Vitamin A Protects the Preterm Lamb Diaphragm Against Adverse Effects of Mechanical Ventilation

Frontiers in Physiology, 2018
Background: Preterm infants are deficient in vitamin A, which is essential for growth and development of the diaphragm. Preterm infants often require mechanical ventilation (MV) for respiratory distress.
Yong Song, Yong Song, Yong Song, Yong Song, MarJanna Dahl, Wendy Leavitt, Jeremy Alvord, Calan Y. Bradford, Kurt H. Albertine, J. Jane Pillow, J. Jane Pillow   +10 more
doaj   +1 more source

Adaptive Support Ventilation Prevents Ventilator-induced Diaphragmatic Dysfunction in Piglet: : an in vivo and in vitro study.

, 2010
International audienceBACKGROUND: Contrary to adaptive support ventilation (ASV), prolonged totally controlled mechanical ventilation (CMV) results in the absence of diaphragm activity and causes ventilator-induced diaphragmatic dysfunction.
Constantin, Jean-Michel, Sebbane, Mustapha, Capdevila, Xavier, Jung, Boris, Hugon, Gerald, Petrof, Basil, Chanques, Gerald, Futier, Emmanuel, Jaber, Samir, Rossel, Nans, Le Goff, Charlotte, Coisel, Yannaël, Matecki, Stefan   +12 more
core   +1 more source

Single fibre cytoarchitecture in ventilator-induced diaphragm dysfunction (VIDD) assessed by quantitative morphometry second harmonic generation imaging: Positive effects of BGP-15 chaperone co-inducer and VBP-15 dissociative corticosteroid treatment. [PDF]

Front Physiol, 2023
Mnuskina S, Bauer J, Wirth-Hücking A, Schneidereit D, Nübler S, Ritter P, Cacciani N, Li M, Larsson L, Friedrich O.   +9 more
europepmc   +1 more source

Sedation Using Propofol Induces Similar Diaphragm Dysfunction and Atrophy during Spontaneous Breathing and Mechanical Ventilation in Rats

, 2014
Mechanical ventilation is crucial for patients with respiratory failure. The mechanical takeover of diaphragm function leads to diaphragm dysfunction and atrophy (ventilator-induced diaphragmatic dysfunction), with an increase in oxidative stress as a ...
Bergs, Ingmar, Brülls, Christian Simon, Weis, Joachim, Bruells, Christian S., Thomas, Debby, Rossaint, Rolf, Bleilevens, Christian, Maes, Karen, Cielen, Nele, Gayan-Ramirez, Ghislaine   +9 more
core   +1 more source

Single-nucleus transcriptomic profiling of the diaphragm during mechanical ventilation

Scientific Reports
Mechanical ventilation contributes to diaphragm atrophy and muscle weakness, which is referred to as ventilator-induced diaphragmatic dysfunction (VIDD). The pathogenesis of VIDD has not been fully understood until recently.
Lei Li, Feng Jiang, Wenyan Hao, Yu Wang, Yaqian Li, Dong Zhang   +5 more
doaj   +1 more source

Patterns and predictors of adherence to diaphragm use in a phase III trial in sub-Saharan Africa: a trajectory analysis.

, 2009
BACKGROUND: We examined diaphragm adherence among 2429 women randomized to the intervention arm (diaphragm + gel + condoms) in Methods for Improving Reproductive Health in Africa, a phase III trial of the diaphragm for HIV prevention in Zimbabwe and ...
van der Straten, Ariane, Shiboski, Stephen, Ramjee, Gita, Moore, Jie, De Bruyn, Guy, Montgomery, Elizabeth T, Chidanyika, Agnes, Padian, Nancy, Kacanek, Deborah, MIRA Team   +9 more
core   +1 more source

ANGIOTENSIN II TYPE 1 RECEPTOR CONTRIBUTES TO VENTILATOR-INDUCED DIAPHRAGM DYSFUNCTION

, 2016
S. E. Hall1, A. J. Smuder2, M. P. Wiggs2, A. B. Morton2, K. J. Sollanek2, S. K. Powers2 1 Boise State University, Boise, ID & 2 University of Florida, Gainesville, FL Mechanical ventilation (MV) is a life-saving intervention for patients in respiratory ...
Morton, AB, Smuder, AJ, Wiggs, MP, Powers, SK, Hall, SE, Sollanek, KJ   +5 more
core