Results 81 to 90 of about 2,969 (154)

Identification of the co-differentially expressed hub genes involved in the endogenous protective mechanism against ventilator-induced diaphragm dysfunction. [PDF]

Skelet Muscle, 2022
Zhang D, Hao W, Niu Q, Xu D, Duan X.
europepmc   +1 more source

Ventilator-induced Diaphragm Dysfunction [PDF]

Anesthesiology, 2012
Ewan C, Goligher, Niall D, Ferguson, Brian P, Kavanagh   +2 more
openaire   +2 more sources

Rationale and design of a mechanistic clinical trial of JAK inhibition to prevent ventilator-induced diaphragm dysfunction. [PDF]

Respir Med, 2021
Shrager JB, Wang Y, Lee M, Nesbit S, Trope W, Konsker H, Fatodu E, Berry MS, Poulstides G, Norton J, Burdon T, Backhus L, Cooke R, Tang H.   +13 more
europepmc   +1 more source

The ReInvigorate Study—phrenic nerve-to-diaphragm stimulation for weaning from mechanical ventilation: a protocol for a randomized pivotal clinical trial

Trials
Background In the United States in 2017, there were an estimated 903,745 hospitalizations involving mechanical ventilation (MV). Complications from ventilation can result in longer hospital stays, increased risk of disability, and increased healthcare ...
Katie Schaaf, Christopher M. Mullin, Kyle W. Cunningham, Jonathan Eaton, Steven A. Conrad   +4 more
doaj   +1 more source

Single fibre cytoarchitecture in ventilator-induced diaphragm dysfunction (VIDD) assessed by quantitative morphometry second harmonic generation imaging: Positive effects of BGP-15 chaperone co-inducer and VBP-15 dissociative corticosteroid treatment. [PDF]

Front Physiol, 2023
Mnuskina S, Bauer J, Wirth-Hücking A, Schneidereit D, Nübler S, Ritter P, Cacciani N, Li M, Larsson L, Friedrich O.   +9 more
europepmc   +1 more source

Prolonged mechanical ventilation alters the expression pattern of angio-neogenetic factors in a pre-clinical rat model.

PLoS ONE, 2013
ObjectiveMechanical ventilation (MV) is a life saving intervention for patients with respiratory failure. Even after 6 hours of MV, diaphragm atrophy and dysfunction (collectively referred to as ventilator-induced diaphragmatic dysfunction, VIDD) occurs ...
Christian S Bruells, Karen Maes, Rolf Rossaint, Debby Thomas, Nele Cielen, Christian Bleilevens, Ingmar Bergs, Ursina Loetscher, Agnes Dreier, Ghislaine Gayan-Ramirez, Brad J Behnke, Joachim Weis   +11 more
doaj   +1 more source

Vitamin A Protects the Preterm Lamb Diaphragm Against Adverse Effects of Mechanical Ventilation

Frontiers in Physiology, 2018
Background: Preterm infants are deficient in vitamin A, which is essential for growth and development of the diaphragm. Preterm infants often require mechanical ventilation (MV) for respiratory distress.
Yong Song, Yong Song, Yong Song, Yong Song, MarJanna Dahl, Wendy Leavitt, Jeremy Alvord, Calan Y. Bradford, Kurt H. Albertine, J. Jane Pillow, J. Jane Pillow   +10 more
doaj   +1 more source

Single-nucleus transcriptomic profiling of the diaphragm during mechanical ventilation

Scientific Reports
Mechanical ventilation contributes to diaphragm atrophy and muscle weakness, which is referred to as ventilator-induced diaphragmatic dysfunction (VIDD). The pathogenesis of VIDD has not been fully understood until recently.
Lei Li, Feng Jiang, Wenyan Hao, Yu Wang, Yaqian Li, Dong Zhang   +5 more
doaj   +1 more source

MOESM1 of The JAK-STAT Pathway Is Critical in Ventilator-Induced Diaphragm Dysfunction

, 2014
Supplementary material, approximately 14541 KB.
Tang, Huibin, Smith, Ira, Hussain, Sabah, Goldberg, Peter, Lee, Myung, Sugiarto, Sista, Godinez, Guillermo, Singh, Baljit, Payan, Donald, Rando, Thomas, Kinsella, Todd, Shrager, Joseph   +11 more
openaire   +1 more source

Multi-center randomized superiority clinical trial in the early phase of mechanically ventilated patients to preserve diaphragm thickness using non-invasive magnetic phrenic nerve stimulation: STIMIT ACTIVATOR 1 pivotal trial

Trials
Background Ventilator-induced diaphragmatic dysfunction (VIDD) occurs in up to 60% of mechanically ventilated patients and prolongs ventilatory dependance.
Annia F. Schreiber, Carles Subirà, Michael Sklar, Marlene Santos, Matthew Ko, Alessandro Panelli, Stefan J. Schaller, Danny Theodore, Daniel D. Rowley, David Watson, Pramod Bonde, Elias N. Baedorf Kassis, Daniel S. Talmor, Marco Ranieri, Ewan C. Goligher, Arthur Slutsky, Laurent J. Brochard   +16 more
doaj   +1 more source