Results 61 to 70 of about 3,803,785 (155)
ABSTRACT Post‐traumatic hiccups are an uncommon but distressing complication of traumatic brain injury (TBI), often resistant to conventional pharmacological agents, and the underlying mechanism may involve central neurological disruption of inhibitory pathways rather than gastrointestinal or metabolic aetiologies. We report a male patient in his early
Rostom Karajeh +4 more
wiley +1 more source
Toll-like Receptor 4 Signaling in Ventilator-induced Diaphragm Atrophy.
BACKGROUND:: Mechanical ventilation induces diaphragm muscle atrophy, which plays a key role in difficult weaning from mechanical ventilation. The signaling pathways involved in ventilator-induced diaphragm atrophy are poorly understood.
Heunks, Leo M.A. +15 more
core +1 more source
Feasibility of transesophageal phrenic nerve stimulation
Background Every year, more than 2.5 million critically ill patients in the ICU are dependent on mechanical ventilation. The positive pressure in the lungs generated by the ventilator keeps the diaphragm passive, which can lead to a loss of myofibers ...
Elisa M. Kaufmann +5 more
doaj +1 more source
Update on the Pathophysiology, Aetiology and Management of Central Sleep Apnoea
ABSTRACT Central sleep apnoea (CSA) of the periodic breathing type occurs during the transition between wakefulness and stage 1 and 2 non‐REM sleep. In adults at sea level, it occurs most commonly due to advanced heart failure (HF) or chronic opioid use and in ~5% of obstructive sleep apnoea patients initiating CPAP.
Sahan D. Chandrasekara +1 more
wiley +1 more source
Mechanical ventilation causes diaphragm dysfunction in newborn lambs
Background Diaphragm weakness occurs rapidly in adult animals treated with mechanical ventilation (MV), but the effects of MV on the neonatal diaphragm have not been determined.
Feng Liang +10 more
doaj +1 more source
A 4D geometric morphometrics workflow to quantify complex biological motion
Abstract Quantifying biological motion is fundamentally tied to quantifying the biological structures that produce that motion. Yet, this dependence makes it essential to decouple motion from static morphology to enable general, comparable analyses across individuals and conditions. In this work, we present a methodological pipeline to study biological
Marta Gómez‐Recio +8 more
wiley +1 more source
Diaphragmatic dysfunction in mechanical ventilation
Purpose of Review: It has become clear from experimental data that prolonged mechanical ventilation can induce diaphragm dysfunction, also known as ventilator-induced diaphragm dysfunction.
Jack J Haitsma, Haitsma, Jack J.
core +1 more source
When CO2 sensing fails: Protective effects of sex hormones and potential mechanisms
Abstract Breathing movements driven by the brainstem rhythmogenic neural networks rely on chemosensory inputs to produce a motor output that is homeostatically adjusted to the prevailing metabolic demand. The central CO2 chemoreflex is a critical component of respiratory neural circuitry, as defects in these sensors cause hypoventilation syndromes ...
Tara A. Janes +2 more
wiley +1 more source
ABSTRACT This retrospective analysis evaluated 12 dogs with hepatocellular carcinoma (HCC) who received stereotactic body radiation therapy (SBRT). Dogs received between 6 and 25 Grey (Gy) per fraction for 1–5 fractions for a total dose of 13–30 Gy. Eleven patients (92%) experienced acute adverse effects (AE), with the majority being VRTOG grade 2–3 ...
Victoria Lee Newberry +3 more
wiley +1 more source
New perspectives on the physiological basis of muscle loss
Experimental Physiology, EarlyView.
Alistair J. Monteyne, Marlou L. Dirks
wiley +1 more source

