Results 41 to 50 of about 2,969 (154)

Electrical stimulation mitigates muscle degradation shift in gene expressions during 12-h mechanical ventilation

Scientific Reports, 2023
Ventilator-induced diaphragm dysfunction (VIDD), a dysfunction of the diaphragm muscle caused by prolonged mechanical ventilation (MV), is an important factor that hinders successful weaning from ventilation.
Hideki Nakai, Yutaka Hirata, Hidemasa Furue, Yoshitaka Oku   +3 more
doaj   +1 more source

Protective effect of methylprednisolone on ventilator-induced diaphragm dysfunction is dose dependent [PDF]

Critical Care, 2010
We previously showed that an acute high dose of corticosteroids (80 mg/kg) with controlled mechanical ventilation (CMV) prevented ventilator‐induced diaphragm dysfunction in rats. We examined whether administration of lower doses of methylprednisolone (5 and 30 mg/kg) would result into a similar protective ...
Maes, K, Agten, A, Smuder, A, Powers, SK, Decramer, M, Gayan-Ramirez, G   +5 more
openaire   +1 more source

Hemorrhagic Shock Sensitized the Diaphragm to Ventilator-Induced Dysfunction through the Activation of IL-6/JAK/STAT Signaling-Mediated Autophagy in Rats

Mediators of Inflammation, 2019
Mechanical ventilation (MV) is a major life support technique for the management of trauma-associated hemorrhagic shock (HS). Ventilator-induced diaphragm dysfunction (VIDD), one of the most common complications of MV, has been well demonstrated in ...
Li-Juan Zhang, Shao-Zhou Ni, Xian-Long Zhou, Yan Zhao   +3 more
doaj   +1 more source

Monitoring and assessment for obstructive sleep apnea

FlexMat, EarlyView.
This review systematically classifies Obstructive Sleep Apnea (OSA) monitoring indicators into three categories: physical, biochemical, and electrophysiological indicators, and lists several methods for each category. Abstract Obstructive sleep apnea (OSA) is a common chronic sleep‐disordered breathing disease characterized by recurrent upper airway ...
Yaowen Xu, Feifei Lin, Shujiao Chen, Zhen You, Shujing Zhu, Weiwei Zhao, Qiang Zhao   +6 more
wiley   +1 more source

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

Rheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina, Ghaydaa Aldabie, Mohammad Abdulsalam, Ali Jawad   +3 more
wiley   +1 more source

Effects of exercise preconditioning and HSP72 on diaphragm muscle function during mechanical ventilation

Journal of Cachexia, Sarcopenia and Muscle, 2019
Background Mechanical ventilation (MV) is a life‐saving measure for patients in respiratory failure. However, prolonged MV results in significant diaphragm atrophy and contractile dysfunction, a condition referred to as ventilator‐induced diaphragm ...
Ashley J. Smuder, Aaron B. Morton, Stephanie E. Hall, Michael P. Wiggs, Bumsoo Ahn, Nicholas R. Wawrzyniak, Kurt J. Sollanek, Kisuk Min, Oh Sung Kwon, W. Bradley Nelson, Scott K. Powers   +10 more
doaj   +1 more source

Phrenic nerve stimulation to prevent diaphragmatic dysfunction and ventilator-induced lung injury

Intensive Care Medicine Experimental, 2023
Side effects of mechanical ventilation, such as ventilator-induced diaphragmatic dysfunction (VIDD) and ventilator-induced lung injury (VILI), occur frequently in critically ill patients.
Alessandro Panelli, Michael A. Verfuß, Martin Dres, Laurent Brochard, Stefan J. Schaller   +4 more
doaj   +1 more source

Update on the Pathophysiology, Aetiology and Management of Central Sleep Apnoea

Respirology, EarlyView.
ABSTRACT Central sleep apnoea (CSA) of the periodic breathing type occurs during the transition between wakefulness and stage 1 and 2 non‐REM sleep. In adults at sea level, it occurs most commonly due to advanced heart failure (HF) or chronic opioid use and in ~5% of obstructive sleep apnoea patients initiating CPAP.
Sahan D. Chandrasekara, Matthew T. Naughton   +1 more
wiley   +1 more source

Metabolomic Profiling of Respiratory Muscles and Lung in Response to Long-Term Controlled Mechanical Ventilation

Frontiers in Cell and Developmental Biology, 2022
Critical illness myopathy (CIM) and ventilator-induced diaphragm dysfunction (VIDD) are characterized by severe muscle wasting, muscle paresis, and extubation failure with subsequent increased medical costs and mortality/morbidity rates in intensive care
Ya Wen, Xiang Zhang, Xiang Zhang, Lars Larsson, Lars Larsson   +4 more
doaj   +1 more source

A 4D geometric morphometrics workflow to quantify complex biological motion

Methods in Ecology and Evolution, EarlyView.
Abstract Quantifying biological motion is fundamentally tied to quantifying the biological structures that produce that motion. Yet, this dependence makes it essential to decouple motion from static morphology to enable general, comparable analyses across individuals and conditions. In this work, we present a methodological pipeline to study biological
Marta Gómez‐Recio, Markus Bastir, Gael Deboeck, Antonella LoMauro, Andrea Aliverti, Véronique Feipel, Barbara Fischer, Philipp Mitteroecker, Benoit Beyer   +8 more
wiley   +1 more source